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Murcko scaffold

4-(2-Pyrimidinyl)morpholine scaffold

241 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
241
With full pages
23
Scaffold SMILES

c1cnc(N2CCOCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(2-Pyrimidinyl)morpholine page
Murcko scaffold c1cnc(N2CCOCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 241 chemicals

4-(4,6-Dimethylpyrimidin-2-yl)morpholine chemical structure, C10H15N3O, CAS 7749-51-1
4-(4,6-Dimethylpyrimidin-2-yl)morpholine
CAS 7749-51-1C10H15N3O
N,6-dimethyl-2-morpholin-4-ylpyrimidin-4-amine chemical structure, C10H16N4O, CAS 381716-92-3
N,6-dimethyl-2-morpholin-4-ylpyrimidin-4-amine
CAS 381716-92-3C10H16N4O
5-Fluoro-2-(morpholin-4-yl)pyrimidin-4-amine chemical structure, C8H11FN4O, CAS 312928-75-9
5-Fluoro-2-(morpholin-4-yl)pyrimidin-4-amine
CAS 312928-75-9C8H11FN4O
2-Morpholino-4,6-difluoropyrimidine chemical structure, C8H9F2N3O, CAS 189003-02-9
2-Morpholino-4,6-difluoropyrimidine
CAS 189003-02-9C8H9F2N3O
4-(4-Iodopyrimidin-2-yl)morpholine chemical structure, C8H10IN3O, CAS 845658-53-9
4-(4-Iodopyrimidin-2-yl)morpholine
CAS 845658-53-9C8H10IN3O
2-Morpholino-4-chloro-6-hydrazinopyrimidine chemical structure, C8H12ClN5O, CAS 24273-66-3
2-Morpholino-4-chloro-6-hydrazinopyrimidine
CAS 24273-66-3C8H12ClN5O
4-(4-Chloropyrimidin-2-yl)morpholine chemical structure, C8H10ClN3O, CAS 24192-96-9
4-(4-Chloropyrimidin-2-yl)morpholine
CAS 24192-96-9C8H10ClN3O
4-(4-Chloro-6-methyl-2-pyrimidinyl)morpholine chemical structure, C9H12ClN3O, CAS 118121-82-7
4-(4-Chloro-6-methyl-2-pyrimidinyl)morpholine
CAS 118121-82-7C9H12ClN3O
4-(4-Hydrazinyl-6-methylpyrimidin-2-yl)morpholine chemical structure, C9H15N5O, CAS 381699-83-8
4-(4-Hydrazinyl-6-methylpyrimidin-2-yl)morpholine
CAS 381699-83-8C9H15N5O
2-(4-Morpholinyl)-5-pyrimidinecarbonitrile chemical structure, C9H10N4O, CAS 400082-62-4
2-(4-Morpholinyl)-5-pyrimidinecarbonitrile
CAS 400082-62-4C9H10N4O
6-Methyl-2-morpholino-4-pyrimidinecarboxamide chemical structure, C10H14N4O2, CAS 439110-92-6
6-Methyl-2-morpholino-4-pyrimidinecarboxamide
CAS 439110-92-6C10H14N4O2
4-(4-Ethoxy-6-methylpyrimidin-2-yl)morpholine chemical structure, C11H17N3O2, CAS 378778-09-7
4-(4-Ethoxy-6-methylpyrimidin-2-yl)morpholine
CAS 378778-09-7C11H17N3O2
5-Chloro-2-(4-morpholinyl)-4-pyrimidinecarboxylic acid chemical structure, C9H10ClN3O3, CAS 327064-07-3
5-Chloro-2-(4-morpholinyl)-4-pyrimidinecarboxylic acid
CAS 327064-07-3C9H10ClN3O3
4-(4,6-Dichloropyrimidin-2-yl)morpholine chemical structure, C8H9Cl2N3O, CAS 10397-13-4
4-(4,6-Dichloropyrimidin-2-yl)morpholine
CAS 10397-13-4C8H9Cl2N3O
5-(tert-Butylsulfonyl)-2-morpholinopyrimidin-4-amine chemical structure, C12H20N4O3S, CAS 175202-11-6
5-(tert-Butylsulfonyl)-2-morpholinopyrimidin-4-amine
CAS 175202-11-6C12H20N4O3S
4-Amino-2-(4-morpholinyl)-5-pyrimidinecarbonitrile chemical structure, C9H11N5O, CAS 78318-43-1
4-Amino-2-(4-morpholinyl)-5-pyrimidinecarbonitrile
CAS 78318-43-1C9H11N5O
Ethyl 2-morpholin-4-yl-4-(trifluoromethyl)pyrimidine-5-carboxylate chemical structure, C12H14F3N3O3, CAS 677706-89-7
Ethyl 2-morpholin-4-yl-4-(trifluoromethyl)pyrimidine-5-carboxylate
CAS 677706-89-7C12H14F3N3O3
Ethyl 4-amino-2-(4-morpholinyl)-5-pyrimidinecarboxylate chemical structure, C11H16N4O3, CAS 78118-88-4
Ethyl 4-amino-2-(4-morpholinyl)-5-pyrimidinecarboxylate
CAS 78118-88-4C11H16N4O3
5-(Isopropylsulfonyl)-2-morpholinopyrimidin-4-amine chemical structure, C11H18N4O3S, CAS 175202-03-6
5-(Isopropylsulfonyl)-2-morpholinopyrimidin-4-amine
CAS 175202-03-6C11H18N4O3S
4-(5-Nitropyrimidin-2-yl)morpholine chemical structure, C8H10N4O3, CAS 65735-66-2
4-(5-Nitropyrimidin-2-yl)morpholine
CAS 65735-66-2C8H10N4O3
4-(4-Methoxy-6-methyl-5-nitropyrimidin-2-yl)morpholine chemical structure, C10H14N4O4, CAS 381198-19-2
4-(4-Methoxy-6-methyl-5-nitropyrimidin-2-yl)morpholine
CAS 381198-19-2C10H14N4O4
4-(4-Methyl-5-nitro-6-propan-2-yloxypyrimidin-2-yl)morpholine chemical structure, C12H18N4O4, CAS 380157-69-7
4-(4-Methyl-5-nitro-6-propan-2-yloxypyrimidin-2-yl)morpholine
CAS 380157-69-7C12H18N4O4
1,2-Ethanediamine, N'-(6-chloro-5-(methylthio)-2-(4-morpholinyl)-4-pyrimidinyl)-N,N-dimethyl- chemical structure, C13H22ClN5OS, CAS 55416-98-3
1,2-Ethanediamine, N'-(6-chloro-5-(methylthio)-2-(4-morpholinyl)-4-pyrimidinyl)-N,N-dimethyl-
CAS 55416-98-3C13H22ClN5OS
1-Propanamine, 3,3'-((5-(methylthio)-2-(4-morpholinyl)-4,6-pyrimidinediyl)bis(oxy))bis(N,N-dimethyl-, dihydrobromide chemical structure, C19H37Br2N5O3S, CAS 57259-24-2
1-Propanamine, 3,3'-((5-(methylthio)-2-(4-morpholinyl)-4,6-pyrimidinediyl)bis(oxy))bis(N,N-dimethyl-, dihydrobromide
CAS 57259-24-2C19H37Br2N5O3S