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Murcko scaffold

Ring system with 2 rings and 15 atoms

8 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 15
Chemicals: 8
With full pages: 5

Scaffold SMILES

O=C(Nc1ccccc1)c1c[nH]c(=S)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Nc1ccccc1)c1c[nH]c(=S)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Methyl 2-[(4-amino-3-ethyl-2-sulfanylidene-1,3-thiazole-5-carbonyl)amino]benzoate chemical structure, C14H15N3O3S2, CAS 862485-67-4

Methyl 2-[(4-amino-3-ethyl-2-sulfanylidene-1,3-thiazole-5-carbonyl)amino]benzoate

CAS 862485-67-4C₁₄H₁₅N₃O₃S₂

Methyl 2-[(4-amino-3-methyl-2-sulfanylidene-1,3-thiazole-5-carbonyl)amino]benzoate chemical structure, C13H13N3O3S2, CAS 877793-76-5

Methyl 2-[(4-amino-3-methyl-2-sulfanylidene-1,3-thiazole-5-carbonyl)amino]benzoate

CAS 877793-76-5C₁₃H₁₃N₃O₃S₂

3-Allyl-4-amino-N-(4-methylphenyl)-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide chemical structure, C14H15N3OS2, CAS 618073-60-2

3-Allyl-4-amino-N-(4-methylphenyl)-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide

CAS 618073-60-2C₁₄H₁₅N₃OS₂

4-Amino-N-(2,4-dichlorophenyl)-3-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide chemical structure, C11H9Cl2N3OS2, CAS 850728-71-1

4-Amino-N-(2,4-dichlorophenyl)-3-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide

CAS 850728-71-1C₁₁H₉Cl₂N₃OS₂

4-Amino-N-(2,4-dimethoxyphenyl)-3-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide chemical structure, C13H15N3O3S2, CAS 850729-34-9

4-Amino-N-(2,4-dimethoxyphenyl)-3-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide

CAS 850729-34-9C₁₃H₁₅N₃O₃S₂

4-Amino-N-(2,6-dichlorophenyl)-3-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide chemical structure, C11H9Cl2N3OS2, CAS 850827-15-5

4-Amino-N-(2,6-dichlorophenyl)-3-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide

CAS 850827-15-5C₁₁H₉Cl₂N₃OS₂

4-Amino-N-(5-chloro-2-methoxyphenyl)-3-methyl-2-sulfanylidene-2,3-dihydro-1,3-thiazole-5-carboxamide chemical structure, C12H12ClN3O2S2, CAS 872455-54-4

4-Amino-N-(5-chloro-2-methoxyphenyl)-3-methyl-2-sulfanylidene-2,3-dihydro-1,3-thiazole-5-carboxamide

CAS 872455-54-4C₁₂H₁₂ClN₃O₂S₂

4-Amino-N-(2-fluorophenyl)-3-methyl-2-sulfanylidene-1,3-thiazole-5-carboxamide chemical structure, C11H10FN3OS2, CAS 877803-15-1

4-Amino-N-(2-fluorophenyl)-3-methyl-2-sulfanylidene-1,3-thiazole-5-carboxamide

CAS 877803-15-1C₁₁H₁₀FN₃OS₂