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Murcko scaffold

6-Phenylpiperidin-2-one scaffold

166 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
166
With full pages
25
Scaffold SMILES

O=C1CCCC(c2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Phenylpiperidin-2-one page
Murcko scaffold O=C1CCCC(c2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 166 chemicals

2-Piperidone, 6-ethyl-6-phenyl- chemical structure, C13H17NO, CAS 6139-34-0
2-Piperidone, 6-ethyl-6-phenyl-
CAS 6139-34-0C13H17NO
5-Nitro-6-phenylpiperidin-2-one chemical structure, C11H12N2O3, CAS 58373-38-9
5-Nitro-6-phenylpiperidin-2-one
CAS 58373-38-9C11H12N2O3
5-Amino-6-phenylpiperidin-2-one chemical structure, C11H14N2O, CAS 906521-90-2
5-Amino-6-phenylpiperidin-2-one
CAS 906521-90-2C11H14N2O
6-(2,3-Dimethoxyphenyl)-5-nitropiperidin-2-one chemical structure, C13H16N2O5, CAS 6623-48-9
6-(2,3-Dimethoxyphenyl)-5-nitropiperidin-2-one
CAS 6623-48-9C13H16N2O5
6-Phenylpiperidin-2-one chemical structure, C11H13NO, CAS 41419-25-4
6-Phenylpiperidin-2-one
CAS 41419-25-4C11H13NO
5-Nitro-6-[2-(propan-2-yloxy)phenyl]piperidin-2-one chemical structure, C14H18N2O4, CAS 430453-52-4
5-Nitro-6-[2-(propan-2-yloxy)phenyl]piperidin-2-one
CAS 430453-52-4C14H18N2O4
(5R,6S)-6-(2,3-Dimethoxyphenyl)-5-nitropiperidin-2-one chemical structure, C13H16N2O5, CAS 61298-30-4
(5R,6S)-6-(2,3-Dimethoxyphenyl)-5-nitropiperidin-2-one
CAS 61298-30-4C13H16N2O5
(5R,6S)-6-(3,4-Dimethoxyphenyl)-5-nitropiperidin-2-one chemical structure, C13H16N2O5, CAS 61298-29-1
(5R,6S)-6-(3,4-Dimethoxyphenyl)-5-nitropiperidin-2-one
CAS 61298-29-1C13H16N2O5
trans-6-(4-Chlorophenyl)-5-nitropiperidin-2-one chemical structure, C11H11ClN2O3, CAS 408373-27-3
trans-6-(4-Chlorophenyl)-5-nitropiperidin-2-one
CAS 408373-27-3C11H11ClN2O3
trans-6-(4-Bromophenyl)-5-nitropiperidin-2-one chemical structure, C11H11BrN2O3, CAS 1219633-48-3
trans-6-(4-Bromophenyl)-5-nitropiperidin-2-one
CAS 1219633-48-3C11H11BrN2O3
2-Piperidinone, 6-phenyl-, (6R)- chemical structure, C11H13NO, CAS 212560-70-8
2-Piperidinone, 6-phenyl-, (6R)-
CAS 212560-70-8C11H13NO
2-Piperidinone, 5-nitro-6-phenyl-, trans- chemical structure, C11H12N2O3, CAS 153186-64-2
2-Piperidinone, 5-nitro-6-phenyl-, trans-
CAS 153186-64-2C11H12N2O3
6-(4-Chlorophenyl)-5-nitropiperidin-2-one chemical structure, C11H11ClN2O3, CAS 58373-41-4
6-(4-Chlorophenyl)-5-nitropiperidin-2-one
CAS 58373-41-4C11H11ClN2O3
6-(4-Methylphenyl)-5-nitro-2-piperidinone chemical structure, C12H14N2O3, CAS 58373-39-0
6-(4-Methylphenyl)-5-nitro-2-piperidinone
CAS 58373-39-0C12H14N2O3
6-(2-Methoxyphenyl)-5-nitropiperidin-2-one chemical structure, C12H14N2O4, CAS 443326-19-0
6-(2-Methoxyphenyl)-5-nitropiperidin-2-one
CAS 443326-19-0C12H14N2O4
6-[4-(Methylsulfanyl)phenyl]-5-nitropiperidin-2-one chemical structure, C12H14N2O3S, CAS 297159-42-3
6-[4-(Methylsulfanyl)phenyl]-5-nitropiperidin-2-one
CAS 297159-42-3C12H14N2O3S
5-Nitro-6-(2,3,4-trimethoxyphenyl)piperidin-2-one chemical structure, C14H18N2O6, CAS 346715-64-8
5-Nitro-6-(2,3,4-trimethoxyphenyl)piperidin-2-one
CAS 346715-64-8C14H18N2O6
6-(2,5-Dimethoxyphenyl)-5-nitropiperidin-2-one chemical structure, C13H16N2O5, CAS 441743-87-9
6-(2,5-Dimethoxyphenyl)-5-nitropiperidin-2-one
CAS 441743-87-9C13H16N2O5
5-Nitro-6-[4-(trifluoromethyl)phenyl]piperidin-2-one chemical structure, C12H11F3N2O3, CAS 430449-32-4
5-Nitro-6-[4-(trifluoromethyl)phenyl]piperidin-2-one
CAS 430449-32-4C12H11F3N2O3
6-(4-Bromo-2,5-dimethoxyphenyl)-5-nitropiperidin-2-one chemical structure, C13H15BrN2O5, CAS 430460-15-4
6-(4-Bromo-2,5-dimethoxyphenyl)-5-nitropiperidin-2-one
CAS 430460-15-4C13H15BrN2O5
6-(3-Bromophenyl)-5-nitropiperidin-2-one chemical structure, C11H11BrN2O3, CAS 430448-64-9
6-(3-Bromophenyl)-5-nitropiperidin-2-one
CAS 430448-64-9C11H11BrN2O3
6-(2,4-Dichlorophenyl)-5-nitropiperidin-2-one chemical structure, C11H10Cl2N2O3, CAS 430451-36-8
6-(2,4-Dichlorophenyl)-5-nitropiperidin-2-one
CAS 430451-36-8C11H10Cl2N2O3
6-(2-Butoxyphenyl)-5-nitropiperidin-2-one chemical structure, C15H20N2O4, CAS 430451-99-3
6-(2-Butoxyphenyl)-5-nitropiperidin-2-one
CAS 430451-99-3C15H20N2O4
6-(3-Bromo-4,5-dimethoxyphenyl)-5-nitropiperidin-2-one chemical structure, C13H15BrN2O5, CAS 442568-64-1
6-(3-Bromo-4,5-dimethoxyphenyl)-5-nitropiperidin-2-one
CAS 442568-64-1C13H15BrN2O5