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Murcko scaffold

Ring system with 1 ring and 5 atoms

60 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
60
With full pages
6
Scaffold SMILES

C1CC[SiH2]C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffold
Murcko scaffold C1CC[SiH2]C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 60 chemicals

Silacyclopentane, 1,1-dichloro- chemical structure, C4H8Cl2Si, CAS 2406-33-9
Silacyclopentane, 1,1-dichloro-
CAS 2406-33-9C4H8Cl2Si
1,1-Dimethyl-1-silacyclopentane chemical structure, C6H14Si, CAS 1072-54-4
1,1-Dimethyl-1-silacyclopentane
CAS 1072-54-4C6H14Si
1,1-Diethylsilolane chemical structure, C8H18Si, CAS 3944-13-6
1,1-Diethylsilolane
CAS 3944-13-6C8H18Si
1-Methoxy-1-methylsilolane chemical structure, C6H14OSi, CAS 90464-98-5
1-Methoxy-1-methylsilolane
CAS 90464-98-5C6H14OSi
1,1,2,5-Tetramethylsilolane chemical structure, C8H18Si, CAS 55956-01-9
1,1,2,5-Tetramethylsilolane
CAS 55956-01-9C8H18Si
1-Methyl-1-ethoxy-1-silacyclopentane chemical structure, C7H16OSi, CAS 74861-48-6
1-Methyl-1-ethoxy-1-silacyclopentane
CAS 74861-48-6C7H16OSi
1-Chloro-1-methylsilolane chemical structure, C5H11ClSi, CAS 2406-31-7
1-Chloro-1-methylsilolane
CAS 2406-31-7C5H11ClSi
[1-(Aminomethyl)silolan-1-yl]methanamine chemical structure, C6H16N2Si, CAS 158585-36-5
[1-(Aminomethyl)silolan-1-yl]methanamine
CAS 158585-36-5C6H16N2Si
1,1,3-Trimethyl-3,4-dinitrosilolane chemical structure, C7H14N2O4Si, CAS 59586-93-5
1,1,3-Trimethyl-3,4-dinitrosilolane
CAS 59586-93-5C7H14N2O4Si
1,1-Bis(chloromethyl)silolane chemical structure, C6H12Cl2Si, CAS 158585-34-3
1,1-Bis(chloromethyl)silolane
CAS 158585-34-3C6H12Cl2Si
Silacyclopentane, 2-ethyl-1,1-dimethoxy- chemical structure, C8H18O2Si, CAS 189300-27-4
Silacyclopentane, 2-ethyl-1,1-dimethoxy-
CAS 189300-27-4C8H18O2Si
trans-3-(Iodomethyl)-1,1,4-trimethyl-silolane chemical structure, C8H17ISi, CAS 144930-15-4
trans-3-(Iodomethyl)-1,1,4-trimethyl-silolane
CAS 144930-15-4C8H17ISi
Silacyclopentane, 1,1-dibutyl- chemical structure, C12H26Si, CAS 18105-47-0
Silacyclopentane, 1,1-dibutyl-
CAS 18105-47-0C12H26Si
1,1,3-Trimethylsilolane chemical structure, C7H16Si, CAS 17936-93-5
1,1,3-Trimethylsilolane
CAS 17936-93-5C7H16Si
1,1-Dimethylsilolane-3,4-diol chemical structure, C6H14O2Si, CAS 81439-46-5
1,1-Dimethylsilolane-3,4-diol
CAS 81439-46-5C6H14O2Si
4-Ethenyl-1,1,2,2,3,3,4-heptamethylsilolane chemical structure, C13H26Si, CAS 88296-46-2
4-Ethenyl-1,1,2,2,3,3,4-heptamethylsilolane
CAS 88296-46-2C13H26Si
1,1-Dimethoxysilolane chemical structure, C6H14O2Si, CAS 18169-68-1
1,1-Dimethoxysilolane
CAS 18169-68-1C6H14O2Si
1-Chloro-1,2-dimethylsilolane chemical structure, C6H13ClSi, CAS 55909-50-7
1-Chloro-1,2-dimethylsilolane
CAS 55909-50-7C6H13ClSi
1-(2,3-Dibromopropyl)-1,2,5-trimethylsilolane chemical structure, C10H20Br2Si, CAS 88916-35-2
1-(2,3-Dibromopropyl)-1,2,5-trimethylsilolane
CAS 88916-35-2C10H20Br2Si
1,1-Dimethylsilolan-3-amine chemical structure, C6H15NSi, CAS 921602-75-7
1,1-Dimethylsilolan-3-amine
CAS 921602-75-7C6H15NSi
1-Vinyl-1-methylsilacyclopentane chemical structure, C7H14Si, CAS 3944-18-1
1-Vinyl-1-methylsilacyclopentane
CAS 3944-18-1C7H14Si
trans-1,1-Dimethylsilolane-3,4-diamine chemical structure, C6H16N2Si, CAS 118747-23-2
trans-1,1-Dimethylsilolane-3,4-diamine
CAS 118747-23-2C6H16N2Si
trans-3,4-Bis(iodomethyl)-1,1-dimethyl-silolane chemical structure, C8H16I2Si, CAS 1334313-86-8
trans-3,4-Bis(iodomethyl)-1,1-dimethyl-silolane
CAS 1334313-86-8C8H16I2Si
1-Methylsilolane chemical structure, C5H12Si, CAS 765-41-3
1-Methylsilolane
CAS 765-41-3C5H12Si