CompoundList
Sign in
Murcko scaffold

1-(1,1-Dioxidotetrahydro-3-thienyl)piperidine scaffold

24 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
24
With full pages
3
Scaffold SMILES

O=S1(=O)CCC(N2CCCCC2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(1,1-Dioxidotetrahydro-3-thienyl)piperidine page
Murcko scaffold O=S1(=O)CCC(N2CCCCC2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

1-(1,1-Dioxidotetrahydro-3-thienyl)piperidine chemical structure, C9H17NO2S, CAS 300716-74-9
1-(1,1-Dioxidotetrahydro-3-thienyl)piperidine
CAS 300716-74-9C9H17NO2S
Thiophene-3-ol, tetrahydro-4-(1-piperidinyl)-, 1,1-dioxide chemical structure, C9H17NO3S, CAS 66335-85-1
Thiophene-3-ol, tetrahydro-4-(1-piperidinyl)-, 1,1-dioxide
CAS 66335-85-1C9H17NO3S
1,1-Dioxo-4-piperidin-1-ylthiolan-3-amine chemical structure, C9H18N2O2S, CAS 882245-68-3
1,1-Dioxo-4-piperidin-1-ylthiolan-3-amine
CAS 882245-68-3C9H18N2O2S
(3S,4S)-3-Hydroxy-4-(piperidin-1-yl)-1lambda6-thiolane-1,1-dione chemical structure, C9H17NO3S, CAS 2165552-87-2
(3S,4S)-3-Hydroxy-4-(piperidin-1-yl)-1lambda6-thiolane-1,1-dione
CAS 2165552-87-2C9H17NO3S
1-(1,1-Dioxidotetrahydro-3-thienyl)-4-piperidinecarboxylic acid chemical structure, C10H17NO4S, CAS 900641-11-4
1-(1,1-Dioxidotetrahydro-3-thienyl)-4-piperidinecarboxylic acid
CAS 900641-11-4C10H17NO4S
1-(1,1-Dioxothiolan-3-yl)piperidine-4-carboxylic acid hydrochloride chemical structure, C10H18ClNO4S, CAS 1052541-78-2
1-(1,1-Dioxothiolan-3-yl)piperidine-4-carboxylic acid hydrochloride
CAS 1052541-78-2C10H18ClNO4S
3-(4-Aminopiperidin-1-yl)tetrahydrothiophene 1,1-dioxide chemical structure, C9H18N2O2S, CAS 1016881-74-5
3-(4-Aminopiperidin-1-yl)tetrahydrothiophene 1,1-dioxide
CAS 1016881-74-5C9H18N2O2S
1-(1,1-Dioxidotetrahydrothiophen-3-yl)piperidine-4-carboxylate chemical structure, C10H16NO4S-, CAS 1007975-25-8
1-(1,1-Dioxidotetrahydrothiophen-3-yl)piperidine-4-carboxylate
CAS 1007975-25-8C10H16NO4S-
3-Amino-4-(piperidin-1-yl)-1lambda6-thiolane-1,1-dione dihydrochloride chemical structure, C9H20Cl2N2O2S, CAS 1240526-33-3
3-Amino-4-(piperidin-1-yl)-1lambda6-thiolane-1,1-dione dihydrochloride
CAS 1240526-33-3C9H20Cl2N2O2S
(3S,4S)-3-Hydroxy-4-(4-methylpiperidin-1-yl)-1lambda6-thiolane-1,1-dione chemical structure, C10H19NO3S, CAS 2165409-95-8
(3S,4S)-3-Hydroxy-4-(4-methylpiperidin-1-yl)-1lambda6-thiolane-1,1-dione
CAS 2165409-95-8C10H19NO3S
3-(3-Hydroxypiperidin-1-yl)tetrahydrothiophene 1,1-dioxide chemical structure, C9H17NO3S, CAS 1247071-46-0
3-(3-Hydroxypiperidin-1-yl)tetrahydrothiophene 1,1-dioxide
CAS 1247071-46-0C9H17NO3S
3-(4-Hydroxypiperidin-1-yl)tetrahydrothiophene 1,1-dioxide chemical structure, C9H17NO3S, CAS 1226231-79-3
3-(4-Hydroxypiperidin-1-yl)tetrahydrothiophene 1,1-dioxide
CAS 1226231-79-3C9H17NO3S
3-[3-(Hydroxymethyl)piperidin-1-yl]-1lambda6-thiolane-1,1-dione chemical structure, C10H19NO3S, CAS 1249585-39-4
3-[3-(Hydroxymethyl)piperidin-1-yl]-1lambda6-thiolane-1,1-dione
CAS 1249585-39-4C10H19NO3S
3-(3-Aminopiperidin-1-yl)tetrahydrothiophene 1,1-dioxide chemical structure, C9H18N2O2S, CAS 1248737-06-5
3-(3-Aminopiperidin-1-yl)tetrahydrothiophene 1,1-dioxide
CAS 1248737-06-5C9H18N2O2S
3-(4-(Aminomethyl)piperidin-1-yl)tetrahydrothiophene 1,1-dioxide chemical structure, C10H20N2O2S, CAS 1251334-83-4
3-(4-(Aminomethyl)piperidin-1-yl)tetrahydrothiophene 1,1-dioxide
CAS 1251334-83-4C10H20N2O2S
3-(4-(Hydroxymethyl)piperidin-1-yl)tetrahydrothiophene 1,1-dioxide chemical structure, C10H19NO3S, CAS 1247186-75-9
3-(4-(Hydroxymethyl)piperidin-1-yl)tetrahydrothiophene 1,1-dioxide
CAS 1247186-75-9C10H19NO3S
tert-Butyl (1-(1,1-dioxidotetrahydrothiophen-3-yl)piperidin-4-yl)carbamate chemical structure, C14H26N2O4S, CAS 2034613-88-0
tert-Butyl (1-(1,1-dioxidotetrahydrothiophen-3-yl)piperidin-4-yl)carbamate
CAS 2034613-88-0C14H26N2O4S
3-{4-[(Dimethylsulfamoyl)amino]piperidin-1-yl}-1lambda6-thiolane-1,1-dione chemical structure, C11H23N3O4S2, CAS 2034335-93-6
3-{4-[(Dimethylsulfamoyl)amino]piperidin-1-yl}-1lambda6-thiolane-1,1-dione
CAS 2034335-93-6C11H23N3O4S2
1-(1,1-Dioxidotetrahydrothiophen-3-yl)piperidine-3-carboxylic acid hydrochloride chemical structure, C10H18ClNO4S, CAS 2098001-06-8
1-(1,1-Dioxidotetrahydrothiophen-3-yl)piperidine-3-carboxylic acid hydrochloride
CAS 2098001-06-8C10H18ClNO4S
1-[(3S,4S)-4-Hydroxy-1,1-dioxo-1lambda6-thiolan-3-yl]piperidine-4-carbonitrile chemical structure, C10H16N2O3S, CAS 2165814-86-6
1-[(3S,4S)-4-Hydroxy-1,1-dioxo-1lambda6-thiolan-3-yl]piperidine-4-carbonitrile
CAS 2165814-86-6C10H16N2O3S
tert-Butyl N-{1-[(3S,4S)-4-hydroxy-1,1-dioxo-1lambda6-thiolan-3-yl]piperidin-4-yl}carbamate chemical structure, C14H26N2O5S, CAS 2380495-63-4
tert-Butyl N-{1-[(3S,4S)-4-hydroxy-1,1-dioxo-1lambda6-thiolan-3-yl]piperidin-4-yl}carbamate
CAS 2380495-63-4C14H26N2O5S
(3S,4S)-3-Hydroxy-4-(4-methoxypiperidin-1-yl)-1lambda6-thiolane-1,1-dione chemical structure, C10H19NO4S, CAS 2165622-04-6
(3S,4S)-3-Hydroxy-4-(4-methoxypiperidin-1-yl)-1lambda6-thiolane-1,1-dione
CAS 2165622-04-6C10H19NO4S
(3S,4S)-3-(4-Ethylpiperidin-1-yl)-4-hydroxy-1lambda6-thiolane-1,1-dione chemical structure, C11H21NO3S, CAS 2165750-45-6
(3S,4S)-3-(4-Ethylpiperidin-1-yl)-4-hydroxy-1lambda6-thiolane-1,1-dione
CAS 2165750-45-6C11H21NO3S
1-(1,1-Dioxothiolan-3-yl)piperidin-3-amine, dihydrochloride chemical structure, C9H20Cl2N2O2S, CAS 2703752-92-3
1-(1,1-Dioxothiolan-3-yl)piperidin-3-amine, dihydrochloride
CAS 2703752-92-3C9H20Cl2N2O2S