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Murcko scaffold

Ring system with 2 rings and 17 atoms

18 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
18
With full pages
13
Scaffold SMILES

O=c1[nH]cc(S(=O)(=O)N2CCCCC2)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cc(S(=O)(=O)N2CCCCC2)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

1-[(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxylic acid chemical structure, C11H15N3O6S, CAS 697258-18-7
1-[(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxylic acid
CAS 697258-18-7C11H15N3O6S
Methyl 1-(1,3,4-trimethyl-2,6-dioxopyrimidin-5-yl)sulfonylpiperidine-4-carboxylate chemical structure, C14H21N3O6S, CAS 893339-83-8
Methyl 1-(1,3,4-trimethyl-2,6-dioxopyrimidin-5-yl)sulfonylpiperidine-4-carboxylate
CAS 893339-83-8C14H21N3O6S
Ethyl 1-(1,3-dimethyl-2,4-dioxopyrimidin-5-yl)sulfonylpiperidine-3-carboxylate chemical structure, C14H21N3O6S, CAS 874806-54-9
Ethyl 1-(1,3-dimethyl-2,4-dioxopyrimidin-5-yl)sulfonylpiperidine-3-carboxylate
CAS 874806-54-9C14H21N3O6S
Ethyl 1-(1,3,4-trimethyl-2,6-dioxopyrimidin-5-yl)sulfonylpiperidine-4-carboxylate chemical structure, C15H23N3O6S, CAS 893338-35-7
Ethyl 1-(1,3,4-trimethyl-2,6-dioxopyrimidin-5-yl)sulfonylpiperidine-4-carboxylate
CAS 893338-35-7C15H23N3O6S
Ethyl 1-(1,3-dimethyl-2,4-dioxopyrimidin-5-yl)sulfonylpiperidine-4-carboxylate chemical structure, C14H21N3O6S, CAS 874806-30-1
Ethyl 1-(1,3-dimethyl-2,4-dioxopyrimidin-5-yl)sulfonylpiperidine-4-carboxylate
CAS 874806-30-1C14H21N3O6S
Methyl 1-(1,3-dimethyl-2,4-dioxopyrimidin-5-yl)sulfonylpiperidine-4-carboxylate chemical structure, C13H19N3O6S, CAS 874806-47-0
Methyl 1-(1,3-dimethyl-2,4-dioxopyrimidin-5-yl)sulfonylpiperidine-4-carboxylate
CAS 874806-47-0C13H19N3O6S
1,3-Dimethyl-5-((4-methylpiperidin-1-yl)sulfonyl)pyrimidine-2,4(1H,3H)-dione chemical structure, C12H19N3O4S, CAS 874806-62-9
1,3-Dimethyl-5-((4-methylpiperidin-1-yl)sulfonyl)pyrimidine-2,4(1H,3H)-dione
CAS 874806-62-9C12H19N3O4S
Ethyl 1-[(2-hydroxy-6-oxo-1,6-dihydropyrimidin-5-yl)sulfonyl]piperidine-4-carboxylate chemical structure, C12H17N3O6S, CAS 897622-91-2
Ethyl 1-[(2-hydroxy-6-oxo-1,6-dihydropyrimidin-5-yl)sulfonyl]piperidine-4-carboxylate
CAS 897622-91-2C12H17N3O6S
2-Hydroxy-5-[(4-methylpiperidin-1-yl)sulfonyl]pyrimidin-4(3H)-one chemical structure, C10H15N3O4S, CAS 897623-00-6
2-Hydroxy-5-[(4-methylpiperidin-1-yl)sulfonyl]pyrimidin-4(3H)-one
CAS 897623-00-6C10H15N3O4S
1,3,6-Trimethyl-5-piperidin-1-ylsulfonylpyrimidine-2,4-dione chemical structure, C12H19N3O4S, CAS 893338-14-2
1,3,6-Trimethyl-5-piperidin-1-ylsulfonylpyrimidine-2,4-dione
CAS 893338-14-2C12H19N3O4S
1,3,6-Trimethyl-5-(4-methylpiperidin-1-yl)sulfonylpyrimidine-2,4-dione chemical structure, C13H21N3O4S, CAS 893341-75-8
1,3,6-Trimethyl-5-(4-methylpiperidin-1-yl)sulfonylpyrimidine-2,4-dione
CAS 893341-75-8C13H21N3O4S
5-((2-Ethylpiperidin-1-yl)sulfonyl)-1,3,6-trimethylpyrimidine-2,4(1H,3H)-dione chemical structure, C14H23N3O4S, CAS 893339-07-6
5-((2-Ethylpiperidin-1-yl)sulfonyl)-1,3,6-trimethylpyrimidine-2,4(1H,3H)-dione
CAS 893339-07-6C14H23N3O4S
1,3,6-Trimethyl-5-((3-methylpiperidin-1-yl)sulfonyl)pyrimidine-2,4(1H,3H)-dione chemical structure, C13H21N3O4S, CAS 893341-68-9
1,3,6-Trimethyl-5-((3-methylpiperidin-1-yl)sulfonyl)pyrimidine-2,4(1H,3H)-dione
CAS 893341-68-9C13H21N3O4S
5-((2-Ethylpiperidin-1-yl)sulfonyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione chemical structure, C13H21N3O4S, CAS 874806-37-8
5-((2-Ethylpiperidin-1-yl)sulfonyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
CAS 874806-37-8C13H21N3O4S
5-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-1,3,6-trimethylpyrimidine-2,4(1H,3H)-dione chemical structure, C14H23N3O4S, CAS 893339-95-2
5-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-1,3,6-trimethylpyrimidine-2,4(1H,3H)-dione
CAS 893339-95-2C14H23N3O4S
1-[(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-4-carboxylic acid chemical structure, C11H15N3O6S, CAS 697257-17-3
1-[(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-4-carboxylic acid
CAS 697257-17-3C11H15N3O6S
5-[(4-Aminopiperidin-1-yl)sulfonyl]pyrimidine-2,4(1H,3H)-dione hydrochloride chemical structure, C9H15ClN4O4S, CAS 2098021-21-5
5-[(4-Aminopiperidin-1-yl)sulfonyl]pyrimidine-2,4(1H,3H)-dione hydrochloride
CAS 2098021-21-5C9H15ClN4O4S
5-[(4-Aminopiperidin-1-yl)sulfonyl]-1,3-dimethylpyrimidine-2,4(1H,3H)-dione hydrochloride chemical structure, C11H19ClN4O4S, CAS 2097978-77-1
5-[(4-Aminopiperidin-1-yl)sulfonyl]-1,3-dimethylpyrimidine-2,4(1H,3H)-dione hydrochloride
CAS 2097978-77-1C11H19ClN4O4S