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Murcko scaffold

Ring system with 4 rings and 27 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
13
With full pages
1
Scaffold SMILES

c1ccc(CCN2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCN2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

Tamolarizine dihydrochloride chemical structure, C27H34Cl2N2O3, CAS 93035-33-7
Tamolarizine dihydrochloride
CAS 93035-33-7C27H34Cl2N2O3
Tamolarizine chemical structure, C27H32N2O3, CAS 128229-52-7
Tamolarizine
CAS 128229-52-7C27H32N2O3
2-(4-Benzhydrylpiperazin-1-yl)-1-(4-chlorophenyl)ethanol chemical structure, C25H27ClN2O, CAS 156810-00-3
2-(4-Benzhydrylpiperazin-1-yl)-1-(4-chlorophenyl)ethanol
CAS 156810-00-3C25H27ClN2O
2-(4-Benzhydrylpiperazin-1-yl)-1-(4-bromophenyl)ethanol chemical structure, C25H27BrN2O, CAS 156810-04-7
2-(4-Benzhydrylpiperazin-1-yl)-1-(4-bromophenyl)ethanol
CAS 156810-04-7C25H27BrN2O
1-Piperazineethanol, 4-(diphenylmethyl)-alpha-(4-hydroxyphenyl)-, monohydrochloride chemical structure, C25H29ClN2O2, CAS 87429-91-2
1-Piperazineethanol, 4-(diphenylmethyl)-alpha-(4-hydroxyphenyl)-, monohydrochloride
CAS 87429-91-2C25H29ClN2O2
1-Piperazineethanol, 4-(diphenylmethyl)-alpha-(4-hydroxyphenyl)-beta-methyl-, (r*,r*)-(+-)-, (r-(r*,r*))-2,3-dihydroxybutanedioate (2:1) (salt) chemical structure, C56H66N4O10, CAS 87429-93-4
1-Piperazineethanol, 4-(diphenylmethyl)-alpha-(4-hydroxyphenyl)-beta-methyl-, (r*,r*)-(+-)-, (r-(r*,r*))-2,3-dihydroxybutanedioate (2:1) (salt)
CAS 87429-93-4C56H66N4O10
1-Piperazineethanol, alpha-(4-chlorophenyl)-4-(diphenylmethyl)-, dihydrochloride chemical structure, C25H29Cl3N2O, CAS 156810-01-4
1-Piperazineethanol, alpha-(4-chlorophenyl)-4-(diphenylmethyl)-, dihydrochloride
CAS 156810-01-4C25H29Cl3N2O
1-Piperazineethanol, alpha-(4-bromophenyl)-4-(diphenylmethyl)-, dihydrochloride chemical structure, C25H29BrCl2N2O, CAS 156810-05-8
1-Piperazineethanol, alpha-(4-bromophenyl)-4-(diphenylmethyl)-, dihydrochloride
CAS 156810-05-8C25H29BrCl2N2O
1-Piperazineethanol, 4-(diphenylmethyl)-alpha-(4-(2-propenyloxy)phenyl)-, monohydrochloride chemical structure, C28H33ClN2O2, CAS 93035-12-2
1-Piperazineethanol, 4-(diphenylmethyl)-alpha-(4-(2-propenyloxy)phenyl)-, monohydrochloride
CAS 93035-12-2C28H33ClN2O2
1-Piperazineethanol, 4-(diphenylmethyl)-alpha-(3,4,5-trimethoxyphenyl)-, monohydrochloride chemical structure, C28H35ClN2O4, CAS 93035-26-8
1-Piperazineethanol, 4-(diphenylmethyl)-alpha-(3,4,5-trimethoxyphenyl)-, monohydrochloride
CAS 93035-26-8C28H35ClN2O4
1-Piperazineethanol, 4-(diphenylmethyl)-alpha-(2,3,4-trimethoxyphenyl)-, dihydrochloride chemical structure, C28H36Cl2N2O4, CAS 93035-28-0
1-Piperazineethanol, 4-(diphenylmethyl)-alpha-(2,3,4-trimethoxyphenyl)-, dihydrochloride
CAS 93035-28-0C28H36Cl2N2O4
1-Piperazineethanol, alpha-(2,4-dimethoxyphenyl)-4-(diphenylmethyl)-, dihydrochloride chemical structure, C27H34Cl2N2O3, CAS 93035-31-5
1-Piperazineethanol, alpha-(2,4-dimethoxyphenyl)-4-(diphenylmethyl)-, dihydrochloride
CAS 93035-31-5C27H34Cl2N2O3
Oxalic acid--1-(diphenylmethyl)-4-(2-phenylethyl)piperazine (1/1) chemical structure, C27H30N2O4, CAS 87887-59-0
Oxalic acid--1-(diphenylmethyl)-4-(2-phenylethyl)piperazine (1/1)
CAS 87887-59-0C27H30N2O4