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Murcko scaffold

Ring system with 4 rings and 27 atoms

17 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
17
With full pages
6
Scaffold SMILES

C(=NN1CCN(C(c2ccccc2)c2ccccc2)CC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=NN1CCN(C(c2ccccc2)c2ccccc2)CC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

4-(Diphenylmethyl)-N-[(E)-(2,3,4-trimethoxyphenyl)methylidene]piperazin-1-amine chemical structure, C27H31N3O3, CAS 314078-37-0
4-(Diphenylmethyl)-N-[(E)-(2,3,4-trimethoxyphenyl)methylidene]piperazin-1-amine
CAS 314078-37-0C27H31N3O3
4-(Diphenylmethyl)-N-[(E)-(2,4,5-trimethoxyphenyl)methylidene]piperazin-1-amine chemical structure, C27H31N3O3, CAS 5784-09-8
4-(Diphenylmethyl)-N-[(E)-(2,4,5-trimethoxyphenyl)methylidene]piperazin-1-amine
CAS 5784-09-8C27H31N3O3
4-(Diphenylmethyl)-N-[(E)-(4-ethoxyphenyl)methylidene]piperazin-1-amine chemical structure, C26H29N3O, CAS 314078-31-4
4-(Diphenylmethyl)-N-[(E)-(4-ethoxyphenyl)methylidene]piperazin-1-amine
CAS 314078-31-4C26H29N3O
(Z)-N-(4-Benzhydrylpiperazin-1-yl)-1-phenylmethanimine chemical structure, C24H25N3, CAS 5785-81-9
(Z)-N-(4-Benzhydrylpiperazin-1-yl)-1-phenylmethanimine
CAS 5785-81-9C24H25N3
N-[(E)-(3-Chlorophenyl)methylidene]-4-(diphenylmethyl)piperazin-1-amine chemical structure, C24H24ClN3, CAS 1697-46-7
N-[(E)-(3-Chlorophenyl)methylidene]-4-(diphenylmethyl)piperazin-1-amine
CAS 1697-46-7C24H24ClN3
(Z)-N-(4-Benzhydrylpiperazin-1-yl)-1-(4-methoxyphenyl)ethanimine chemical structure, C26H29N3O, CAS 331867-99-3
(Z)-N-(4-Benzhydrylpiperazin-1-yl)-1-(4-methoxyphenyl)ethanimine
CAS 331867-99-3C26H29N3O
(Z)-N-(4-Benzhydrylpiperazin-1-yl)-1-(4-chlorophenyl)ethanimine chemical structure, C25H26ClN3, CAS 329707-49-5
(Z)-N-(4-Benzhydrylpiperazin-1-yl)-1-(4-chlorophenyl)ethanimine
CAS 329707-49-5C25H26ClN3
4-(Diphenylmethyl)-N-[(1Z)-1-(4-nitrophenyl)ethylidene]piperazin-1-amine chemical structure, C25H26N4O2, CAS 329707-54-2
4-(Diphenylmethyl)-N-[(1Z)-1-(4-nitrophenyl)ethylidene]piperazin-1-amine
CAS 329707-54-2C25H26N4O2
N-[(E)-(3,4-Dichlorophenyl)methylidene]-4-(diphenylmethyl)piperazin-1-amine chemical structure, C24H23Cl2N3, CAS 31639-51-7
N-[(E)-(3,4-Dichlorophenyl)methylidene]-4-(diphenylmethyl)piperazin-1-amine
CAS 31639-51-7C24H23Cl2N3
Methyl 4-(((4-benzhydryl-1-piperazinyl)imino)methyl)benzoate chemical structure, C26H27N3O2, CAS 314078-30-3
Methyl 4-(((4-benzhydryl-1-piperazinyl)imino)methyl)benzoate
CAS 314078-30-3C26H27N3O2
4-(Diphenylmethyl)-N-[(E)-(3,4,5-trimethoxyphenyl)methylidene]piperazin-1-amine chemical structure, C27H31N3O3, CAS 1697-56-9
4-(Diphenylmethyl)-N-[(E)-(3,4,5-trimethoxyphenyl)methylidene]piperazin-1-amine
CAS 1697-56-9C27H31N3O3
N-[(E)-(2,5-Dimethoxyphenyl)methylidene]-4-(diphenylmethyl)piperazin-1-amine chemical structure, C26H29N3O2, CAS 314078-28-9
N-[(E)-(2,5-Dimethoxyphenyl)methylidene]-4-(diphenylmethyl)piperazin-1-amine
CAS 314078-28-9C26H29N3O2
4-[(E)-(4-Benzhydrylpiperazin-1-yl)iminomethyl]-N,N-diethylaniline chemical structure, C28H34N4, CAS 31639-49-3
4-[(E)-(4-Benzhydrylpiperazin-1-yl)iminomethyl]-N,N-diethylaniline
CAS 31639-49-3C28H34N4
2-(((4-Benzhydryl-1-piperazinyl)imino)methyl)-6-methoxyphenol chemical structure, C25H27N3O2, CAS 314078-16-5
2-(((4-Benzhydryl-1-piperazinyl)imino)methyl)-6-methoxyphenol
CAS 314078-16-5C25H27N3O2
2-Allyl-6-(((4-benzhydryl-1-piperazinyl)imino)methyl)phenol chemical structure, C27H29N3O, CAS 314078-55-2
2-Allyl-6-(((4-benzhydryl-1-piperazinyl)imino)methyl)phenol
CAS 314078-55-2C27H29N3O
(E)-2-(((4-Benzhydrylpiperazin-1-yl)imino)methyl)-6-ethoxyphenol chemical structure, C26H29N3O2, CAS 314078-14-3
(E)-2-(((4-Benzhydrylpiperazin-1-yl)imino)methyl)-6-ethoxyphenol
CAS 314078-14-3C26H29N3O2
(E)-2-(((4-Benzhydrylpiperazin-1-yl)imino)methyl)-4-bromophenol chemical structure, C24H24BrN3O, CAS 314078-32-5
(E)-2-(((4-Benzhydrylpiperazin-1-yl)imino)methyl)-4-bromophenol
CAS 314078-32-5C24H24BrN3O