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Murcko scaffold

6-(Piperazin-1-yl)-9H-purine scaffold

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
27
With full pages
4
Scaffold SMILES

c1nc(N2CCNCC2)c2[nH]cnc2n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-(Piperazin-1-yl)-9H-purine page
Murcko scaffold c1nc(N2CCNCC2)c2[nH]cnc2n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

6-(4-Methylpiperazin-1-yl)-7H-purine chemical structure, C10H14N6, CAS 99172-01-7
6-(4-Methylpiperazin-1-yl)-7H-purine
CAS 99172-01-7C10H14N6
2-[4-(7H-Purin-6-yl)piperazin-1-yl]ethanol chemical structure, C11H16N6O, CAS 537667-10-0
2-[4-(7H-Purin-6-yl)piperazin-1-yl]ethanol
CAS 537667-10-0C11H16N6O
1-Piperazinecarboxylic acid, 4-(1H-purin-6-yl)-, ethyl ester chemical structure, C12H16N6O2, CAS 84806-94-0
1-Piperazinecarboxylic acid, 4-(1H-purin-6-yl)-, ethyl ester
CAS 84806-94-0C12H16N6O2
6-(Piperazin-1-yl)-9H-purine chemical structure, C9H12N6, CAS 245449-95-0
6-(Piperazin-1-yl)-9H-purine
CAS 245449-95-0C9H12N6
tert-Butyl 4-(9H-purin-6-yl)piperazine-1-carboxylate chemical structure, C14H20N6O2, CAS 121370-56-7
tert-Butyl 4-(9H-purin-6-yl)piperazine-1-carboxylate
CAS 121370-56-7C14H20N6O2
9-Methyl-6-(piperazin-1-yl)-9H-purine chemical structure, C10H14N6, CAS 139653-63-7
9-Methyl-6-(piperazin-1-yl)-9H-purine
CAS 139653-63-7C10H14N6
tert-Butyl 4-(8-methyl-9H-purin-6-yl)piperazine-1-carboxylate chemical structure, C15H22N6O2, CAS 121370-63-6
tert-Butyl 4-(8-methyl-9H-purin-6-yl)piperazine-1-carboxylate
CAS 121370-63-6C15H22N6O2
2-Chloro-6-(4-methylpiperazin-1-yl)-7H-purine chemical structure, C10H13ClN6, CAS 121371-16-2
2-Chloro-6-(4-methylpiperazin-1-yl)-7H-purine
CAS 121371-16-2C10H13ClN6
6-(Piperazin-1-yl)-9H-purin-2-amine chemical structure, C9H13N7, CAS 139653-73-9
6-(Piperazin-1-yl)-9H-purin-2-amine
CAS 139653-73-9C9H13N7
2-Ethyl-9-methyl-6-(piperazin-1-yl)-9H-purine chemical structure, C12H18N6, CAS 121370-50-1
2-Ethyl-9-methyl-6-(piperazin-1-yl)-9H-purine
CAS 121370-50-1C12H18N6
6-(Piperazin-1-yl)-9H-purin-2-amine hydrochloride chemical structure, C9H14ClN7, CAS 1179370-34-3
6-(Piperazin-1-yl)-9H-purin-2-amine hydrochloride
CAS 1179370-34-3C9H14ClN7
6-(4-Ethylpiperazin-1-yl)-7H-purine chemical structure, C11H16N6, CAS 881051-09-8
6-(4-Ethylpiperazin-1-yl)-7H-purine
CAS 881051-09-8C11H16N6
2-Chloro-6-piperazin-1-yl-9H-purine chemical structure, C9H11ClN6, CAS 1105192-82-2
2-Chloro-6-piperazin-1-yl-9H-purine
CAS 1105192-82-2C9H11ClN6
6-(4-Methylpiperazin-1-yl)-9H-purin-2-amine chemical structure, C10H15N7, CAS 1196993-60-8
6-(4-Methylpiperazin-1-yl)-9H-purin-2-amine
CAS 1196993-60-8C10H15N7
6-(Piperazin-1-yl)-9H-purine hydrochloride chemical structure, C9H13ClN6, CAS 1179486-17-9
6-(Piperazin-1-yl)-9H-purine hydrochloride
CAS 1179486-17-9C9H13ClN6
2-Chloro-6-piperazin-1-yl-9H-purine dihydrochloride chemical structure, C9H13Cl3N6, CAS 1351612-64-0
2-Chloro-6-piperazin-1-yl-9H-purine dihydrochloride
CAS 1351612-64-0C9H13Cl3N6
9-Ethyl-6-(piperazin-1-yl)-9H-purine chemical structure, C11H16N6, CAS 1554330-46-9
9-Ethyl-6-(piperazin-1-yl)-9H-purine
CAS 1554330-46-9C11H16N6
2-Chloro-6-(piperazin-1-yl)-9H-purine hydrochloride chemical structure, C9H12Cl2N6, CAS 2406235-09-2
2-Chloro-6-(piperazin-1-yl)-9H-purine hydrochloride
CAS 2406235-09-2C9H12Cl2N6
6-(4-Methanesulfonylpiperazin-1-yl)-9-methyl-9H-purine chemical structure, C11H16N6O2S, CAS 2549040-41-5
6-(4-Methanesulfonylpiperazin-1-yl)-9-methyl-9H-purine
CAS 2549040-41-5C11H16N6O2S
9-(2-Methoxyethyl)-6-(piperazin-1-yl)-9H-purine chemical structure, C12H18N6O, CAS 2640889-18-3
9-(2-Methoxyethyl)-6-(piperazin-1-yl)-9H-purine
CAS 2640889-18-3C12H18N6O
tert-Butyl 4-[9-(2-methoxyethyl)-9H-purin-6-yl]piperazine-1-carboxylate chemical structure, C17H26N6O3, CAS 2640948-96-3
tert-Butyl 4-[9-(2-methoxyethyl)-9H-purin-6-yl]piperazine-1-carboxylate
CAS 2640948-96-3C17H26N6O3
9-Methyl-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]-9H-purine chemical structure, C12H15F3N6, CAS 2741944-95-4
9-Methyl-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]-9H-purine
CAS 2741944-95-4C12H15F3N6
tert-Butyl 4-(9-ethyl-9H-purin-6-yl)piperazine-1-carboxylate chemical structure, C16H24N6O2, CAS 2742051-39-2
tert-Butyl 4-(9-ethyl-9H-purin-6-yl)piperazine-1-carboxylate
CAS 2742051-39-2C16H24N6O2
9-(2-Methoxyethyl)-6-(4-methylpiperazin-1-yl)-9H-purine chemical structure, C13H20N6O, CAS 2877680-43-6
9-(2-Methoxyethyl)-6-(4-methylpiperazin-1-yl)-9H-purine
CAS 2877680-43-6C13H20N6O