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Murcko scaffold

2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-phenylacetamide scaffold

188 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
188
With full pages
62
Scaffold SMILES

O=C(CN1C(=O)c2ccccc2C1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-phenylacetamide page
Murcko scaffold O=C(CN1C(=O)c2ccccc2C1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 188 chemicals

2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-phenylacetamide chemical structure, C16H12N2O3, CAS 2017-94-9
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-phenylacetamide
CAS 2017-94-9C16H12N2O3
4-{[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl]amino}benzoic acid chemical structure, C17H12N2O5, CAS 111148-65-3
4-{[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl]amino}benzoic acid
CAS 111148-65-3C17H12N2O5
2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N-P-tolyl-acetamide chemical structure, C17H14N2O3, CAS 7473-88-3
2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N-P-tolyl-acetamide
CAS 7473-88-3C17H14N2O3
Ethyl 4-[[2-(1,3-dioxoisoindol-2-yl)acetyl]amino]benzoate chemical structure, C19H16N2O5, CAS 7508-58-9
Ethyl 4-[[2-(1,3-dioxoisoindol-2-yl)acetyl]amino]benzoate
CAS 7508-58-9C19H16N2O5
2-(1,3-Dioxoisoindol-2-yl)-N-(3-ethynylphenyl)acetamide chemical structure, C18H12N2O3, CAS 294891-35-3
2-(1,3-Dioxoisoindol-2-yl)-N-(3-ethynylphenyl)acetamide
CAS 294891-35-3C18H12N2O3
2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N-p-tolyl-propionamide chemical structure, C18H16N2O3, CAS 140244-40-2
2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N-p-tolyl-propionamide
CAS 140244-40-2C18H16N2O3
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-(3-fluorophenyl)acetamide chemical structure, C16H11FN2O3, CAS 328288-30-8
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-(3-fluorophenyl)acetamide
CAS 328288-30-8C16H11FN2O3
N-(2,5-Dimethoxy-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetamide chemical structure, C18H16N2O5, CAS 302558-89-0
N-(2,5-Dimethoxy-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetamide
CAS 302558-89-0C18H16N2O5
2-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-(2-ethyl-6-methylphenyl)acetamide chemical structure, C19H18N2O3, CAS 303794-29-8
2-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-(2-ethyl-6-methylphenyl)acetamide
CAS 303794-29-8C19H18N2O3
Methyl 4-{[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl]amino}benzoate chemical structure, C18H14N2O5, CAS 76491-87-7
Methyl 4-{[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl]amino}benzoate
CAS 76491-87-7C18H14N2O5
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-(4-ethylphenyl)acetamide chemical structure, C18H16N2O3, CAS 34023-99-9
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-(4-ethylphenyl)acetamide
CAS 34023-99-9C18H16N2O3
N-(2,3-Dimethylphenyl)-2-(1,3-dioxoisoindol-2-yl)acetamide chemical structure, C18H16N2O3, CAS 349087-60-1
N-(2,3-Dimethylphenyl)-2-(1,3-dioxoisoindol-2-yl)acetamide
CAS 349087-60-1C18H16N2O3
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-ethyl-N-(2-methylphenyl)acetamide chemical structure, C19H18N2O3, CAS 6108-65-2
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-ethyl-N-(2-methylphenyl)acetamide
CAS 6108-65-2C19H18N2O3
2-(1,3-Dioxoisoindol-2-yl)-N-(2-methyl-5-nitrophenyl)acetamide chemical structure, C17H13N3O5, CAS 349426-14-8
2-(1,3-Dioxoisoindol-2-yl)-N-(2-methyl-5-nitrophenyl)acetamide
CAS 349426-14-8C17H13N3O5
N-(3,4-Difluoro-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetamide chemical structure, C16H10F2N2O3, CAS 349428-53-1
N-(3,4-Difluoro-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetamide
CAS 349428-53-1C16H10F2N2O3
2-(1,3-Dioxo-2-isoindolyl)-N-(3-nitrophenyl)acetamide chemical structure, C16H11N3O5, CAS 54371-59-4
2-(1,3-Dioxo-2-isoindolyl)-N-(3-nitrophenyl)acetamide
CAS 54371-59-4C16H11N3O5
N-(2,6-Dimethylphenyl)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetamide chemical structure, C18H16N2O3, CAS 71344-56-4
N-(2,6-Dimethylphenyl)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetamide
CAS 71344-56-4C18H16N2O3
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-(2-ethoxyphenyl)acetamide chemical structure, C18H16N2O4, CAS 335207-97-1
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-(2-ethoxyphenyl)acetamide
CAS 335207-97-1C18H16N2O4
2-{[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl]amino}benzoic acid chemical structure, C17H12N2O5, CAS 56654-86-5
2-{[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl]amino}benzoic acid
CAS 56654-86-5C17H12N2O5
N-(3-Chloro-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetamide chemical structure, C16H11ClN2O3, CAS 34023-98-8
N-(3-Chloro-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetamide
CAS 34023-98-8C16H11ClN2O3
N-(4-Chloro-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetamide chemical structure, C16H11ClN2O3, CAS 111148-63-1
N-(4-Chloro-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetamide
CAS 111148-63-1C16H11ClN2O3
RefChem:381559 chemical structure, C17H14N2O3, CAS 76492-00-7
RefChem:381559
CAS 76492-00-7C17H14N2O3
N-(2-Chlorophenyl)-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)acetamide chemical structure, C16H11ClN2O3, CAS 139088-91-8
N-(2-Chlorophenyl)-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)acetamide
CAS 139088-91-8C16H11ClN2O3
2-(1,3-Dioxoisoindol-2-yl)-N-(2-fluorophenyl)acetamide chemical structure, C16H11FN2O3, CAS 303794-28-7
2-(1,3-Dioxoisoindol-2-yl)-N-(2-fluorophenyl)acetamide
CAS 303794-28-7C16H11FN2O3