Murcko scaffold
N-Benzyl-1H-indole-2-carboxamide scaffold
50 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 19
- Chemicals
- 50
- With full pages
- 10
Scaffold SMILES
O=C(NCc1ccccc1)c1cc2ccccc2[nH]1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=C(NCc1ccccc1)c1cc2ccccc2[nH]1](/scaffold/AYMFXIQFBKQBGU-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 50 chemicals
N-(4-Chlorobenzyl)-1H-indole-2-carboxamide
CAS 852173-83-2C16H13ClN2O
N-Benzyl-4,5,6-trimethoxy-N-methyl-1H-indole-2-carboxamide
CAS 902029-28-1C20H22N2O4
N-Benzyl-5-fluoro-N-methyl-1H-indole-2-carboxamide
CAS 902313-59-1C17H15FN2O
N-Benzyl-N-ethyl-4,5,6-trimethoxy-1H-indole-2-carboxamide
CAS 902313-61-5C21H24N2O4
N-Benzyl-5,6-dimethoxy-N-methyl-1H-indole-2-carboxamide
CAS 900873-98-5C19H20N2O3
5-Fluoro-N-(1-phenylethyl)-1H-indole-2-carboxamide
CAS 902031-78-1C17H15FN2O
N-Benzyl-N-ethyl-5-methoxy-3-methyl-1H-indole-2-carboxamide
CAS 902306-55-2C20H22N2O2
N-Benzyl-5-methoxy-N,3-dimethyl-1H-indole-2-carboxamide
CAS 902311-13-1C19H20N2O2
acetic acid chemical structure, C19H18N2O4, CAS 957023-30-2](/s/APRQGWNHKABZEG-QGZVFWFLSA-N.svg)
(2R)-[(5-Methoxy-1-methyl-1H-indole-2-carbonyl)amino](phenyl)acetic acid
CAS 957023-30-2C19H18N2O4
![(2R)-{[(5-Fluoro-1-methyl-1H-indol-2-yl)carbonyl]amino}(phenyl)ethanoic acid chemical structure, C18H15FN2O3, CAS 1173685-74-9](/s/BLCFYCADRMSJKO-MRXNPFEDSA-N.svg)
(2R)-{[(5-Fluoro-1-methyl-1H-indol-2-yl)carbonyl]amino}(phenyl)ethanoic acid
CAS 1173685-74-9C18H15FN2O3
N-Benzyl-5-bromo-1H-indole-2-carboxamide
CAS 352359-16-1C16H13BrN2O
N-Benzyl-1H-indole-2-carboxamide
CAS 69808-76-0C16H14N2O
N-(2-Chlorobenzyl)-1H-indole-2-carboxamide
CAS 1154328-01-4C16H13ClN2O
N-(3-Chlorobenzyl)-1H-indole-2-carboxamide
CAS 1154327-90-8C16H13ClN2O
N-(3-Fluorobenzyl)-5-hydroxy-1H-indole-2-carboxamide
CAS 265311-92-0C16H13FN2O2
5-Hydroxy-N-(4-hydroxybenzyl)-1H-indole-2-carboxamide
CAS 265311-85-1C16H14N2O3
![4-[[[(5-Hydroxy-1H-indol-2-yl)carbonyl]amino]methyl]benzoic acid chemical structure, C17H14N2O4, CAS 265311-87-3](/s/WOIOGQRWTIJPBK-UHFFFAOYSA-N.svg)
4-[[[(5-Hydroxy-1H-indol-2-yl)carbonyl]amino]methyl]benzoic acid
CAS 265311-87-3C17H14N2O4
![Methyl 4-[[[(5-hydroxy-1H-indol-2-yl)carbonyl]amino]methyl]benzoate chemical structure, C18H16N2O4, CAS 265311-88-4](/s/JXIGIOAIZLJRQR-UHFFFAOYSA-N.svg)
Methyl 4-[[[(5-hydroxy-1H-indol-2-yl)carbonyl]amino]methyl]benzoate
CAS 265311-88-4C18H16N2O4
5-Hydroxy-1H-indole-2-carboxylic acid 3-hydroxy-benzylamide
CAS 265311-84-0C16H14N2O3
5-Hydroxy-N-(2-hydroxybenzyl)-1H-indole-2-carboxamide
CAS 265311-83-9C16H14N2O3
![(2S)-2-[(4,7-Dimethoxy-1H-indol-2-yl)formamido]-2-phenylacetic acid chemical structure, C19H18N2O5, CAS 956951-92-1](/s/IWFKXMXHKHTPHT-INIZCTEOSA-N.svg)
(2S)-2-[(4,7-Dimethoxy-1H-indol-2-yl)formamido]-2-phenylacetic acid
CAS 956951-92-1C19H18N2O5
5-Fluoro-N-(3-hydroxybenzyl)-1H-indole-2-carboxamide
CAS 518058-84-9C16H13FN2O2
N-(4-Hydroxybenzyl)-1H-indole-2-carboxamide
CAS 265311-96-4C16H14N2O2
N-(1-Phenylethyl)-1H-indole-2-carboxamide
CAS 18103-59-8C17H16N2O
- 4-{[(1H-Indol-2-yl)formamido]methyl}benzoic acid1019395-38-0C17H14N2O3
- 6-Hydroxy-N-(3-hydroxybenzyl)-1H-indole-2-carboxamide265311-94-2C16H14N2O3
- 4-Hydroxy-N-(3-hydroxybenzyl)-1H-indole-2-carboxamide265311-97-5C16H14N2O3
- 5,6-Dihydroxy-N-(3-hydroxybenzyl)-1H-indole-2-carboxamide265311-93-1C16H14N2O4
- 6-Bromo-N-(3-methoxybenzyl)-1H-indole-2-carboxamide1296201-73-4C17H15BrN2O2
- 5-Chloro-N-(3-ethoxy-4-methoxybenzyl)-1H-indole-2-carboxamide1252817-52-9C19H19ClN2O3
- N-[Cyano(2-methoxyphenyl)methyl]-4-fluoro-1H-indole-2-carboxamide1355787-32-4C18H14FN3O2
- N-(4-Fluorobenzyl)-4,7-dimethoxy-1-methyl-1H-indole-2-carboxamide1351688-87-3C19H19FN2O3
- N-(2-Fluorobenzyl)-4,7-dimethoxy-1-methyl-1H-indole-2-carboxamide1351703-57-5C19H19FN2O3
- 4,7-Dimethoxy-N-(2-methoxybenzyl)-1-methyl-1H-indole-2-carboxamide1351687-50-7C20H22N2O4
- 1-(Ethoxymethyl)-N-[(2-iodophenyl)methyl]-1H-indole-2-carboxamide923603-79-6C19H19IN2O2
- N-(3,4-Dimethoxybenzyl)-4,7-dimethoxy-1-methyl-1H-indole-2-carboxamide1351689-27-4C21H24N2O5
- 4,7-Dimethoxy-N-(4-sulfamoylbenzyl)-1H-indole-2-carboxamide1574464-03-1C18H19N3O5S
- 2-[(4,7-Dimethoxy-1H-indol-2-yl)formamido]-2-phenylacetic acid2137488-28-7C19H18N2O5
- N-Benzyl-1-methyl-N-(prop-2-yn-1-yl)-1H-indole-2-carboxamide1273578-11-2C20H18N2O
- N-[Cyano(2-methoxyphenyl)methyl]-5-methoxy-1H-indole-2-carboxamide1808870-41-8C19H17N3O3
- 2-[4-[(1~{S})-1-[[4,5-bis(chloranyl)-1,6-dimethyl-indol-2-yl]carbonylamino]-2-oxidanyl-ethyl]phenyl]sulfonylethanoic acid2244452-09-1C21H20Cl2N2O6S
- Ethyl 2-[4-[(1S)-1-[(4,5-dichloro-1,6-dimethylindole-2-carbonyl)amino]-2-hydroxyethyl]phenyl]sulfonylacetate2244451-48-5C23H24Cl2N2O6S
- N-[[4-(Aminomethyl)-2-fluorophenyl]methyl]-1-ethylindole-2-carboxamide, hydrochloride2418727-62-3C19H21ClFN3O
- N-(2-Amino-1-phenylethyl)-5-chloro-1-methyl-1H-indole-2-carboxamide2376069-91-7C18H18ClN3O
- Hdac-IN-272763368-89-2C20H22N4O2
- N-[1-(2-Chlorophenyl)ethyl]-7-methyl-1H-indole-2-carboxamide2411759-26-5C18H17ClN2O
- N-[(2-Chlorophenyl)methyl]-7-methyl-1H-indole-2-carboxamide2411759-23-2C17H15ClN2O
- HDAC-IN-27 (dihydrochloride)3069831-25-7C20H24Cl2N4O2
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