Murcko scaffold
N-Benzyl-1-benzofuran-2-carboxamide scaffold
55 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 19
- Chemicals
- 55
- With full pages
- 20
Scaffold SMILES
O=C(NCc1ccccc1)c1cc2ccccc2o1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 55 chemicals
![N-[(4-Propan-2-ylphenyl)methyl]-1-benzofuran-2-carboxamide chemical structure, C19H19NO2, CAS 300863-45-0](/s/QOTVHMLDLUGXBY-UHFFFAOYSA-N.svg)
N-[(4-Propan-2-ylphenyl)methyl]-1-benzofuran-2-carboxamide
CAS 300863-45-0C19H19NO2
N-Benzyl-1-benzofuran-2-carboxamide
CAS 21315-63-9C16H13NO2
N-Benzyl-N-methyl-1-benzofuran-2-carboxamide
CAS 304889-46-1C17H15NO2
N-(2-Chlorobenzyl)-1-benzofuran-2-carboxamide
CAS 690675-83-3C16H12ClNO2
N-(4-Methoxybenzyl)-3-methyl-1-benzofuran-2-carboxamide
CAS 617695-08-6C18H17NO3
![N-[(4-Methoxyphenyl)methyl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide chemical structure, C20H21NO3, CAS 622349-46-6](/s/JKEFDOVTMGATIY-UHFFFAOYSA-N.svg)
N-[(4-Methoxyphenyl)methyl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide
CAS 622349-46-6C20H21NO3
N-Benzyl-5-chloro-3-methyl-1-benzofuran-2-carboxamide
CAS 714261-34-4C17H14ClNO2
![5-Ethyl-N-[(4-methoxyphenyl)methyl]-3-methyl-1-benzofuran-2-carboxamide chemical structure, C20H21NO3, CAS 714261-51-5](/s/YIKCHDYIEBIVQL-UHFFFAOYSA-N.svg)
5-Ethyl-N-[(4-methoxyphenyl)methyl]-3-methyl-1-benzofuran-2-carboxamide
CAS 714261-51-5C20H21NO3
![3,5,6-Trimethyl-N-[(4-methylphenyl)methyl]-1-benzofuran-2-carboxamide chemical structure, C20H21NO2, CAS 622349-43-3](/s/BDMGIDZRUXCSJU-UHFFFAOYSA-N.svg)
3,5,6-Trimethyl-N-[(4-methylphenyl)methyl]-1-benzofuran-2-carboxamide
CAS 622349-43-3C20H21NO2
![3,5-Dimethyl-N-[(4-methylphenyl)methyl]-1-benzofuran-2-carboxamide chemical structure, C19H19NO2, CAS 620587-78-2](/s/RCRAVSQIVXBOCF-UHFFFAOYSA-N.svg)
3,5-Dimethyl-N-[(4-methylphenyl)methyl]-1-benzofuran-2-carboxamide
CAS 620587-78-2C19H19NO2
![3,6,7-Trimethyl-N-[(4-sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide chemical structure, C19H20N2O4S, CAS 724741-29-1](/s/UTFNKOUSVJRLOG-UHFFFAOYSA-N.svg)
3,6,7-Trimethyl-N-[(4-sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide
CAS 724741-29-1C19H20N2O4S
![3,4,6-Trimethyl-N-[(4-sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide chemical structure, C19H20N2O4S, CAS 724741-32-6](/s/IVHZLZRFYIACML-UHFFFAOYSA-N.svg)
3,4,6-Trimethyl-N-[(4-sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide
CAS 724741-32-6C19H20N2O4S
![5-Ethyl-3-methyl-N-[(4-sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide chemical structure, C19H20N2O4S, CAS 724741-48-4](/s/CVLCCGDWTYZMMM-UHFFFAOYSA-N.svg)
5-Ethyl-3-methyl-N-[(4-sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide
CAS 724741-48-4C19H20N2O4S
![N-[4-(Aminosulfonyl)benzyl]-3,6-dimethyl-1-benzofuran-2-carboxamide chemical structure, C18H18N2O4S, CAS 714261-77-5](/s/KSSZCNDRFBEMPN-UHFFFAOYSA-N.svg)
N-[4-(Aminosulfonyl)benzyl]-3,6-dimethyl-1-benzofuran-2-carboxamide
CAS 714261-77-5C18H18N2O4S
![N-[4-(Aminosulfonyl)benzyl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide chemical structure, C19H20N2O4S, CAS 622350-06-5](/s/WYKOEAHQFQZETQ-UHFFFAOYSA-N.svg)
N-[4-(Aminosulfonyl)benzyl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide
CAS 622350-06-5C19H20N2O4S
![3,5-Dimethyl-N-[(4-sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide chemical structure, C18H18N2O4S, CAS 620588-09-2](/s/QHMBPDQNNHMQTK-UHFFFAOYSA-N.svg)
3,5-Dimethyl-N-[(4-sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide
CAS 620588-09-2C18H18N2O4S
![5-Fluoro-3-methyl-N-[(4-sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide chemical structure, C17H15FN2O4S, CAS 823827-60-7](/s/REZFYDIMIYAGMY-UHFFFAOYSA-N.svg)
5-Fluoro-3-methyl-N-[(4-sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide
CAS 823827-60-7C17H15FN2O4S
N-Benzyl-5-bromo-3-methyl-1-benzofuran-2-carboxamide
CAS 714261-41-3C17H14BrNO2
N-Benzyl-5-fluoro-3-methyl-1-benzofuran-2-carboxamide
CAS 823827-37-8C17H14FNO2
N-Benzyl-3-methyl-1-benzofuran-2-carboxamide
CAS 325730-85-6C17H15NO2
![N-[(4-Sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide chemical structure, C16H14N2O4S, CAS 90141-25-6](/s/YUSCQPDHMQPESK-UHFFFAOYSA-N.svg)
N-[(4-Sulfamoylphenyl)methyl]-1-benzofuran-2-carboxamide
CAS 90141-25-6C16H14N2O4S
![N-[[4-(Difluoromethoxy)phenyl]methyl]-N,3-dimethyl-1-benzofuran-2-carboxamide chemical structure, C19H17F2NO3, CAS 796051-01-9](/s/KXQGZSLRMAFXNI-UHFFFAOYSA-N.svg)
N-[[4-(Difluoromethoxy)phenyl]methyl]-N,3-dimethyl-1-benzofuran-2-carboxamide
CAS 796051-01-9C19H17F2NO3
![N-[(2-Chloro-6-fluorophenyl)methyl]-N-methyl-1-benzofuran-2-carboxamide chemical structure, C17H13ClFNO2, CAS 851879-66-8](/s/PSONHICANHKNKT-UHFFFAOYSA-N.svg)
N-[(2-Chloro-6-fluorophenyl)methyl]-N-methyl-1-benzofuran-2-carboxamide
CAS 851879-66-8C17H13ClFNO2
![N-[(4-Fluorophenyl)methyl]-1-benzofuran-2-carboxamide chemical structure, C16H12FNO2, CAS 879162-48-8](/s/FVQLDFLFMBSNAV-UHFFFAOYSA-N.svg)
N-[(4-Fluorophenyl)methyl]-1-benzofuran-2-carboxamide
CAS 879162-48-8C16H12FNO2
- 1 suppliersN-(1-Phenylethyl)-1-benzofuran-2-carboxamide304889-25-6C17H15NO2
- 2-[(1-Benzofuran-2-yl)formamido]-2-phenylacetic acid1028026-58-5C17H13NO4
- N-(2,4-Dichlorobenzyl)-3-methyl-1-benzofuran-2-carboxamide588674-65-1C17H13Cl2NO2
- N-[(2-Chlorophenyl)methyl]-N-methyl-1-benzofuran-2-carboxamide852214-31-4C17H14ClNO2
- N-Methyl-N-[(4-methylsulfanylphenyl)methyl]-1-benzofuran-2-carboxamide852867-95-9C18H17NO2S
- N-[(2-Methoxyphenyl)methyl]-N-methyl-1-benzofuran-2-carboxamide851288-06-7C18H17NO3
- 3-Methyl-N-(1-phenylpropyl)-1-benzofuran-2-carboxamide894622-06-1C19H19NO2
- N-[(2-Chlorophenyl)methyl]-3-methyl-1-benzofuran-2-carboxamide950237-79-3C17H14ClNO2
- 7-Chloro-N-[(3-fluorophenyl)methyl]-N,3-dimethyl-1-benzofuran-2-carboxamide878102-25-1C18H15ClFNO2
- N-[[4-(Dimethylamino)phenyl]methyl]-N-methyl-1-benzofuran-2-carboxamide878109-05-8C19H20N2O2
- N-Benzyl-7-chloro-N,3-dimethyl-1-benzofuran-2-carboxamide878124-29-9C18H16ClNO2
- 5-(N,N-Diethylsulfamoyl)-3-methyl-N-(4-methylbenzyl)benzofuran-2-carboxamide687569-15-9C22H26N2O4S
- 4-{[(1-Benzofuran-2-carbonyl)amino]methyl}benzene-1-sulfonyl chloride90141-23-4C16H12ClNO4S
- N-Benzyl-5-(N,N-diethylsulfamoyl)-3-methylbenzofuran-2-carboxamide687568-85-0C21H24N2O4S
- 5-Chloro-3,6-dimethyl-N-(4-sulfamoylbenzyl)-1-benzofuran-2-carboxamide879934-60-8C18H17ClN2O4S
- N-Benzyl-5-chloro-N,3,6-trimethyl-1-benzofuran-2-carboxamide880786-76-5C19H18ClNO2
- N-(2-Methoxybenzyl)-5-methyl-1-benzofuran-2-carboxamide950237-87-3C18H17NO3
- 3,5-Dimethyl-N-(1-phenylethyl)-1-benzofuran-2-carboxamide951894-76-1C19H19NO2
- 4-{[(1-Benzofuran-2-yl)formamido]methyl}benzoic acid890979-38-1C17H13NO4
- 7-Methoxy-N-(4-sulfamoylbenzyl)benzofuran-2-carboxamide951956-76-6C17H16N2O5S
- N-(4-Ethoxybenzyl)-7-methoxy-1-benzofuran-2-carboxamide928924-91-8C19H19NO4
- N-Benzyl-3,6-dimethyl-1-benzofuran-2-carboxamide959239-11-3C18H17NO2
- N-((2-Aminophenyl)methyl)-N-methyl-1-benzofuran-2-carboxamide1153887-12-7C17H16N2O2
- N-[1-(4-Fluorophenyl)ethyl]-3-methyl-1-benzofuran-2-carboxamide1009168-22-2C18H16FNO2
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(CN1C(=O)c2ccccc2C1=O)Nc1ccccc162 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]c(NN=Cc3ccccc3)nc2[nH]1](/scaffold/CHHJWHRZURXTFZ-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]c(NN=Cc3ccccc3)nc2[nH]135 chemicals
O=C(CN1C(=O)c2ccccc2S1(=O)=O)Nc1ccccc123 chemicals
O=C(Nc1ccccc1)Nc1nc2ccccc2s119 chemicals
O=C(Cc1ccccc1)Nc1cc2c(s1)CNCC218 chemicals
C(=NNc1ccccc1)C1=Nc2ccccc2C115 chemicals
O=C(Cc1ccccc1)Nc1nc2ccccc2s115 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]c(CNCc3ccccc3)nc2[nH]1](/scaffold/UVIPRNPUIHSMKT-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]c(CNCc3ccccc3)nc2[nH]115 chemicals![Scaffold O=C(NCc1nc2ccccc2[nH]1)c1ccccc1](/scaffold/DLPWNQUPBLICPH-UHFFFAOYSA-N/structure.svg)
O=C(NCc1nc2ccccc2[nH]1)c1ccccc112 chemicals![Scaffold O=C(NCc1ccccc1)c1cc2ccccc2[nH]1](/scaffold/AYMFXIQFBKQBGU-UHFFFAOYSA-N/structure.svg)
O=C(NCc1ccccc1)c1cc2ccccc2[nH]110 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]c(NCCc3ccccc3)nc2[nH]1](/scaffold/SHGZCTVZCGSROM-UHFFFAOYSA-N/structure.svg)
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