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Murcko scaffold

1,8-Naphthyridine scaffold

608 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
608
With full pages
70
Scaffold SMILES

c1cnc2ncccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,8-Naphthyridine page
Murcko scaffold c1cnc2ncccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 608 chemicals

1,8-Naphthyridine, 2-methyl- chemical structure, C9H8N2, CAS 1569-16-0
1,8-Naphthyridine, 2-methyl-
CAS 1569-16-0C9H8N2
7-Chloro-1,8-naphthyridin-2-amine chemical structure, C8H6ClN3, CAS 15944-33-9
7-Chloro-1,8-naphthyridin-2-amine
CAS 15944-33-9C8H6ClN3
2-Amino-5,7-dimethyl-1,8-naphthyridine chemical structure, C10H11N3, CAS 39565-07-6
2-Amino-5,7-dimethyl-1,8-naphthyridine
CAS 39565-07-6C10H11N3
1,8-Naphthyridine chemical structure, C8H6N2, CAS 254-60-4
1,8-Naphthyridine
CAS 254-60-4C8H6N2
1,8-Naphthyridine, 2,7-difluoro- chemical structure, C8H4F2N2, CAS 56595-11-0
1,8-Naphthyridine, 2,7-difluoro-
CAS 56595-11-0C8H4F2N2
1,8-Naphthyridine,2,3,4,5,6,7-hexafluoro- chemical structure, C8F6N2, CAS 56595-12-1
1,8-Naphthyridine,2,3,4,5,6,7-hexafluoro-
CAS 56595-12-1C8F6N2
Ketone, methyl 2-methyl-1,8-naphthyridin-3-yl chemical structure, C11H10N2O, CAS 5174-87-8
Ketone, methyl 2-methyl-1,8-naphthyridin-3-yl
CAS 5174-87-8C11H10N2O
4-((5,7-Dimethyl-1,8-naphthyridin-2-yl)amino)-4-oxobutanoic acid chemical structure, C14H15N3O3, CAS 198221-13-5
4-((5,7-Dimethyl-1,8-naphthyridin-2-yl)amino)-4-oxobutanoic acid
CAS 198221-13-5C14H15N3O3
7-Chloro-2,4-dimethyl-1,8-naphthyridine chemical structure, C10H9ClN2, CAS 77223-21-3
7-Chloro-2,4-dimethyl-1,8-naphthyridine
CAS 77223-21-3C10H9ClN2
N-(7-Chloro-1,8-naphthyridin-2-yl)acetamide chemical structure, C10H8ClN3O, CAS 53788-34-4
N-(7-Chloro-1,8-naphthyridin-2-yl)acetamide
CAS 53788-34-4C10H8ClN3O
N-(7-Chloro-4-methyl-1,8-naphthyridin-2-yl)acetamide chemical structure, C11H10ClN3O, CAS 17884-14-9
N-(7-Chloro-4-methyl-1,8-naphthyridin-2-yl)acetamide
CAS 17884-14-9C11H10ClN3O
N,N-Bis(2-chloroethyl)-2,7-dimethyl-1,8-naphthyridin-4-amine chemical structure, C14H17Cl2N3, CAS 91860-15-0
N,N-Bis(2-chloroethyl)-2,7-dimethyl-1,8-naphthyridin-4-amine
CAS 91860-15-0C14H17Cl2N3
2-[[7-[Bis(2-hydroxyethyl)amino]-1,8-naphthyridin-2-yl]-(2-hydroxyethyl)amino]ethanol chemical structure, C16H24N4O4, CAS 91860-12-7
2-[[7-[Bis(2-hydroxyethyl)amino]-1,8-naphthyridin-2-yl]-(2-hydroxyethyl)amino]ethanol
CAS 91860-12-7C16H24N4O4
2,2'-[(5,7-Dimethyl-1,8-naphthyridin-2-yl)azanediyl]di(ethan-1-ol) chemical structure, C14H19N3O2, CAS 91860-11-6
2,2'-[(5,7-Dimethyl-1,8-naphthyridin-2-yl)azanediyl]di(ethan-1-ol)
CAS 91860-11-6C14H19N3O2
N,N-Bis(2-chloroethyl)-7-methyl-2-propyl-1,8-naphthyridin-4-amine chemical structure, C16H21Cl2N3, CAS 91860-16-1
N,N-Bis(2-chloroethyl)-7-methyl-2-propyl-1,8-naphthyridin-4-amine
CAS 91860-16-1C16H21Cl2N3
2,2'-[(7-Methyl-2-propyl-1,8-naphthyridin-4-yl)azanediyl]di(ethan-1-ol) chemical structure, C16H23N3O2, CAS 91860-05-8
2,2'-[(7-Methyl-2-propyl-1,8-naphthyridin-4-yl)azanediyl]di(ethan-1-ol)
CAS 91860-05-8C16H23N3O2
2,7-Dichloro-4-methyl-1,8-naphthyridine chemical structure, C9H6Cl2N2, CAS 58035-56-6
2,7-Dichloro-4-methyl-1,8-naphthyridine
CAS 58035-56-6C9H6Cl2N2
5-Methyl-1,8-naphthyridin-2-amine chemical structure, C9H9N3, CAS 1568-92-9
5-Methyl-1,8-naphthyridin-2-amine
CAS 1568-92-9C9H9N3
2,7-Dichloro-5-methyl-1,8-naphthyridin-3-amine chemical structure, C9H7Cl2N3, CAS 909078-22-4
2,7-Dichloro-5-methyl-1,8-naphthyridin-3-amine
CAS 909078-22-4C9H7Cl2N3
2,4-Dichloro-3,7-dimethyl-1,8-naphthyridine chemical structure, C10H8Cl2N2, CAS 483342-52-5
2,4-Dichloro-3,7-dimethyl-1,8-naphthyridine
CAS 483342-52-5C10H8Cl2N2
4-Methyl-1,8-naphthyridine chemical structure, C9H8N2, CAS 1569-17-1
4-Methyl-1,8-naphthyridine
CAS 1569-17-1C9H8N2
3-Methyl-1,8-naphthyridine chemical structure, C9H8N2, CAS 14759-22-9
3-Methyl-1,8-naphthyridine
CAS 14759-22-9C9H8N2
1,8-Naphthyridine, 2,5-dimethyl- chemical structure, C10H10N2, CAS 14759-23-0
1,8-Naphthyridine, 2,5-dimethyl-
CAS 14759-23-0C10H10N2
3,5-Dimethyl-1,8-naphthyridine chemical structure, C10H10N2, CAS 14757-46-1
3,5-Dimethyl-1,8-naphthyridine
CAS 14757-46-1C10H10N2