Murcko scaffold
2-Mercaptobenzoxazole scaffold
141 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 141
- With full pages
- 25
Scaffold SMILES
S=c1[nH]c2ccccc2o1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold S=c1[nH]c2ccccc2o1](/scaffold/FLFWJIBUZQARMD-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 141 chemicals
3-Methyl-1,3-benzoxazole-2(3H)-thione
CAS 13673-63-7C8H7NOS
Butyl 6-chloro-2-thioxo-1,3-benzoxazole-3(2H)-carboxylate
CAS 49740-32-1C12H12ClNO3S
RefChem:381500
CAS 31315-64-7C11H10ClNO2S
3-(2-Thioxo-benzooxazol-3-yl)-propionic acid
CAS 41405-51-0C10H9NO3S
5-Chloro-2-mercaptobenzoxazole
CAS 22876-19-3C7H4ClNOS
5-Methyl-1,3-benzoxazole-2(3H)-thione
CAS 22876-22-8C8H7NOS
2-Mercaptobenzoxazole
CAS 2382-96-9C7H5NOS
5,7-Dichloro-2(3H)-benzoxazolethione
CAS 98279-11-9C7H3Cl2NOS
![5-Nitrobenzo[D]oxazole-2-thiol chemical structure, C7H4N2O3S, CAS 22876-21-7](/s/FQOGSTGLRLMQOV-UHFFFAOYSA-N.svg)
5-Nitrobenzo[D]oxazole-2-thiol
CAS 22876-21-7C7H4N2O3S
2-Mercaptobenzooxazole-5-carboxylic acid
CAS 7341-98-2C8H5NO3S
3-Propyl-2(3H)-benzoxazolethione
CAS 32602-80-5C10H11NOS
2(3H)-Benzoxazolethione, 3,5-dimethyl-
CAS 88882-29-5C9H9NOS
6-Methyl-1,3-benzoxazole-2-thiol
CAS 23417-29-0C8H7NOS
5,7-Dichloro-6-methyl-1,3-benzoxazole-2-thiol
CAS 199293-12-4C8H5Cl2NOS
2-Methoxyethyl 6-nitro-2-sulfanylidene-1,3-benzoxazole-3-carboxylate
CAS 313498-47-4C11H10N2O6S
6-Nitro-benzooxazole-2-thiol
CAS 14541-93-6C7H4N2O3S
6-Chlorobenzoxazole-2(3H)-thione
CAS 22876-20-6C7H4ClNOS
3-(2-Thioxo-1,3-benzoxazol-3(2H)-yl)propanenitrile
CAS 41405-46-3C10H8N2OS
N,N-Diethyl-2-sulfanyl-1,3-benzoxazole-5-sulfonamide
CAS 24962-46-7C11H14N2O3S2
N,N-Dimethyl-2-sulfanyl-1,3-benzoxazole-5-sulfonamide
CAS 24962-47-8C9H10N2O3S2
5-(Ethylsulfonyl)-1,3-benzoxazole-2-thiol
CAS 155559-80-1C9H9NO3S2
5-Methoxy-1,3-benzoxazole-2(3H)-thione
CAS 49559-83-3C8H7NO2S
![4,6-Dichlorobenzo[d]oxazole-2-thiol chemical structure, C7H3Cl2NOS, CAS 218930-35-9](/s/MCZFXLQGFXFSII-UHFFFAOYSA-N.svg)
4,6-Dichlorobenzo[d]oxazole-2-thiol
CAS 218930-35-9C7H3Cl2NOS
5-(Trifluoromethyl)-2(3H)-benzoxazolethione
CAS 13451-80-4C8H4F3NOS
- 4-Hydroxy-2(3H)-benzoxazolethione73713-92-5C7H5NO2S
- 3-Buten-2-one, 4-(2-thioxo-3(2H)-benzoxazolyl)-88235-12-5C11H9NO2S
- 1-Hexen-3-one, 5-methyl-1-(2-thioxo-3(2H)-benzoxazolyl)-88235-04-5C14H15NO2S
- 1-Penten-3-one, 1-(2-thioxo-3(2H)-benzoxazolyl)-88235-10-3C12H11NO2S
- 1 suppliers7-Chloro-2-mercaptobenzoxazole51793-93-2C7H4ClNOS
- 1-Hexen-3-one, 1-(2-thioxo-3(2H)-benzoxazolyl)-88235-08-9C13H13NO2S
- 5-Chloro-6-nitro-1,3-benzoxazole-2-thiol199293-10-2C7H3ClN2O3S
- 2-Mercapto-1,3-benzoxazole-5-carboxylic acid methyl ester72730-39-3C9H7NO3S
- 1-Hepten-3-one, 1-(2-thioxo-3(2H)-benzoxazolyl)-88235-06-7C14H15NO2S
- 2(3H)-Benzoxazolethione, 5-(1-methylethyl)-90921-57-6C10H11NOS
- 5-Ethoxycarbonyl-2-mercaptobenzoxazole162959-44-6C10H9NO3S
- 2-Thioxo-2,3-dihydro-1,3-benzoxazole-5-carbonitrile93794-41-3C8H4N2OS
- 2-Mercapto-7-methylbenzoxazole93794-43-5C8H7NOS
- 5-Ethyl-2(3H)-benzo[D]oxazolethione93794-42-4C9H9NOS
- 5-Chloro-7-methyl-1,3-benzoxazole-2-thiol93794-45-7C8H6ClNOS
- 6-Methoxy-3H-benzooxazole-2-thione13895-04-0C8H7NO2S
- 3 suppliers5-Bromo-1,3-benzoxazole-2-thiol439607-87-1C7H4BrNOS
- 2(3H)-Benzoxazolethione, 5,6-dichloro-71865-29-7C7H3Cl2NOS
- 2(3H)-Benzoxazolethione, 5-chloro-6-methyl-93794-40-2C8H6ClNOS
- 3 suppliers5-Fluorobenzoxazole-2-thiol13451-78-0C7H4FNOS
- 5-tert-Butyl-1,3-benzoxazole-2-thiol53146-48-8C11H13NOS
- 5-Chloro-6,7-dimethyl-2-mercaptobenzoxazole199293-11-3C9H8ClNOS
- 4-Methyl-1,3-benzoxazole-2-thiol93794-44-6C8H7NOS
- 2(3H)-Benzoxazolethione, 5,7-dimethyl-89227-88-3C9H9NOS
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1ccc2[nH]ccc2c1](/scaffold/SIKJAQJRHWYJAI-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ccc2c12,455 chemicals![Scaffold c1ccc2[nH]cnc2c1](/scaffold/HYZJCKYKOHLVJF-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]cnc2c11,206 chemicals![Scaffold c1ccc2[nH]ncc2c1](/scaffold/BAXOFTOLAUCFNW-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ncc2c1795 chemicals
c1ccc2scnc2c1756 chemicals
c1ccc2occc2c1632 chemicals
c1ccc2c(c1)CCC2621 chemicals
c1ccc2c(c1)OCO2536 chemicals
c1ccc2sccc2c1529 chemicals
c1ccn2ccnc2c1525 chemicals
c1ccc2c(c1)CCN2440 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]cnc2[nH]1](/scaffold/LRFVTYWOQMYALW-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]cnc2[nH]1411 chemicals
O=C1NC(=O)c2ccccc21352 chemicals