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Murcko scaffold

N-1,4-Benzodioxane-2-carbonyl piperazine scaffold

22 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 18
Chemicals: 22
With full pages: 4

Scaffold SMILES

O=C(C1COc2ccccc2O1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the N-1,4-Benzodioxane-2-carbonyl piperazine page

Murcko scaffold O=C(C1COc2ccccc2O1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

(S)-1,4-Benzodioxan-2-carboxypiperazine chemical structure, C13H16N2O3, CAS 401941-54-6

(S)-1,4-Benzodioxan-2-carboxypiperazine

CAS 401941-54-6C₁₃H₁₆N₂O₃

(R)-1,4-Benzodioxan-2-carboxypiperazine chemical structure, C13H16N2O3, CAS 860173-98-4

(R)-1,4-Benzodioxan-2-carboxypiperazine

CAS 860173-98-4C₁₃H₁₆N₂O₃

N-1,4-Benzodioxane-2-carbonyl piperazine chemical structure, C13H16N2O3, CAS 70918-00-2

N-1,4-Benzodioxane-2-carbonyl piperazine

CAS 70918-00-2C₁₃H₁₆N₂O₃

1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride chemical structure, C13H17ClN2O3, CAS 70918-74-0

1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride

CAS 70918-74-0C₁₃H₁₇ClN₂O₃

2,3-Dihydro-1,4-benzodioxin-3-yl-(4-propylpiperazin-1-yl)methanone chemical structure, C16H22N2O3, CAS 374908-19-7

2,3-Dihydro-1,4-benzodioxin-3-yl-(4-propylpiperazin-1-yl)methanone

CAS 374908-19-7C₁₆H₂₂N₂O₃

2H,3H-Benzo[e]1,4-dioxin-2-yl 4-ethylpiperazinyl ketone chemical structure, C15H20N2O3, CAS 21867-88-9

2H,3H-Benzo[e]1,4-dioxin-2-yl 4-ethylpiperazinyl ketone

CAS 21867-88-9C₁₅H₂₀N₂O₃

1-(Chloroacetyl)-4-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine chemical structure, C15H17ClN2O4, CAS 857041-80-6

1-(Chloroacetyl)-4-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine

CAS 857041-80-6C₁₅H₁₇ClN₂O₄

(2,3-Dihydrobenzo[B][1,4]dioxin-2-yl)(4-(2-hydroxyethyl)piperazin-1-yl) methanone chemical structure, C15H20N2O4, CAS 219851-02-2

(2,3-Dihydrobenzo[B][1,4]dioxin-2-yl)(4-(2-hydroxyethyl)piperazin-1-yl) methanone

CAS 219851-02-2C₁₅H₂₀N₂O₄

4-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]-N-ethyl-1-piperazineacetamide chemical structure, C17H23N3O4, CAS 1060812-86-3

4-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]-N-ethyl-1-piperazineacetamide

CAS 1060812-86-3C₁₇H₂₃N₃O₄

1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine-d8 chemical structure, C13H16N2O3, CAS 1006717-20-9

1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine-d8

CAS 1006717-20-9C₁₃H₁₆N₂O₃

4-Boc-1-(1,4-benzodioxan-2-ylcarbonyl)piperazine chemical structure, C18H24N2O5, CAS 1076199-22-8

4-Boc-1-(1,4-benzodioxan-2-ylcarbonyl)piperazine

CAS 1076199-22-8C₁₈H₂₄N₂O₅

4-Boc-1-(1,4-benzodioxan-2-ylcarbonyl)piperazine-d8 chemical structure, C18H24N2O5, CAS 1189968-99-7

4-Boc-1-(1,4-benzodioxan-2-ylcarbonyl)piperazine-d8

CAS 1189968-99-7C₁₈H₂₄N₂O₅

1-(2,3-Dihydro-1,4-benzodioxine-2-carbonyl)-4-(2,2,2-trifluoroethyl)piperazine chemical structure, C15H17F3N2O3, CAS 1235379-58-4

1-(2,3-Dihydro-1,4-benzodioxine-2-carbonyl)-4-(2,2,2-trifluoroethyl)piperazine

CAS 1235379-58-4C₁₅H₁₇F₃N₂O₃

tert-Butyl 4-(2,3-dihydrobenzo[b][1,4]dioxine-2-carbonyl)-2-methylpiperazine-1-carboxylate chemical structure, C19H26N2O5, CAS 1353978-12-7

tert-Butyl 4-(2,3-dihydrobenzo[b][1,4]dioxine-2-carbonyl)-2-methylpiperazine-1-carboxylate

CAS 1353978-12-7C₁₉H₂₆N₂O₅

(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(3-methylpiperazin-1-yl)methanone hydrochloride chemical structure, C14H19ClN2O3, CAS 1353980-53-6

(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(3-methylpiperazin-1-yl)methanone hydrochloride

CAS 1353980-53-6C₁₄H₁₉ClN₂O₃

4-(tert-Butoxycarbonyl)-1-(2,3-dihydrobenzo[b][1,4]dioxine-2-carbonyl)piperazine-2-carboxylic acid chemical structure, C19H24N2O7, CAS 1420795-25-0

4-(tert-Butoxycarbonyl)-1-(2,3-dihydrobenzo[b][1,4]dioxine-2-carbonyl)piperazine-2-carboxylic acid

CAS 1420795-25-0C₁₉H₂₄N₂O₇

tert-Butyl 4-(2,3-dihydrobenzo[b][1,4]dioxine-2-carbonyl)-3-methylpiperazine-1-carboxylate chemical structure, C19H26N2O5, CAS 1420901-16-1

tert-Butyl 4-(2,3-dihydrobenzo[b][1,4]dioxine-2-carbonyl)-3-methylpiperazine-1-carboxylate

CAS 1420901-16-1C₁₉H₂₆N₂O₅

(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(2-methylpiperazin-1-yl)methanone hydrochloride chemical structure, C14H19ClN2O3, CAS 1420964-03-9

(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(2-methylpiperazin-1-yl)methanone hydrochloride

CAS 1420964-03-9C₁₄H₁₉ClN₂O₃

1-(2,3-Dihydrobenzo[b][1,4]dioxine-2-carbonyl)piperazine-2-carboxylic acid hydrochloride chemical structure, C14H17ClN2O5, CAS 1420784-68-4

1-(2,3-Dihydrobenzo[b][1,4]dioxine-2-carbonyl)piperazine-2-carboxylic acid hydrochloride

CAS 1420784-68-4C₁₄H₁₇ClN₂O₅

4-(2,3-Dihydrobenzo[b][1,4]dioxine-2-carbonyl)piperazine-2-carboxylic acid chemical structure, C14H16N2O5, CAS 1420796-80-0

4-(2,3-Dihydrobenzo[b][1,4]dioxine-2-carbonyl)piperazine-2-carboxylic acid

CAS 1420796-80-0C₁₄H₁₆N₂O₅

1-[4-(2,3-Dihydro-1,4-benzodioxine-2-carbonyl)piperazin-1-yl]prop-2-en-1-one chemical structure, C16H18N2O4, CAS 2093821-77-1

1-[4-(2,3-Dihydro-1,4-benzodioxine-2-carbonyl)piperazin-1-yl]prop-2-en-1-one

CAS 2093821-77-1C₁₆H₁₈N₂O₄

4-(2,3-Dihydro-1,4-benzodioxine-3-carbonyl)piperazine-1-sulfonyl fluoride chemical structure, C13H15FN2O5S, CAS 2411201-43-7

4-(2,3-Dihydro-1,4-benzodioxine-3-carbonyl)piperazine-1-sulfonyl fluoride

CAS 2411201-43-7C₁₃H₁₅FN₂O₅S