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Murcko scaffold

2-((6-Benzyl-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)-N-phenylacetamide scaffold

141 chemicals on CompoundList share this ring system.

Rings: 5
Scaffold atoms: 34
Chemicals: 141
With full pages: 3

Scaffold SMILES

O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccccc1)S2(=O)=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-((6-Benzyl-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)-N-phenylacetamide page

Murcko scaffold O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccccc1)S2(=O)=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 141 of 141 chemicals

N-(4-Fluoro-2-methylphenyl)-2-((6-(2-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide chemical structure, C27H23FN4O3S2, CAS 932476-41-0

N-(4-Fluoro-2-methylphenyl)-2-((6-(2-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide

CAS 932476-41-0C₂₇H₂₃FN₄O₃S₂

$2-({9-[(4-Chlorophenyl)methyl]-8,8-dioxo-8lambda6-thia-3,5,9-triazatricyclo[8.4.0.0^{2,7}]tetradeca-1(14),2(7),3,5,10,12-hexaen-4-yl}sulfanyl)-N-phenylacetamide chemical structure, C25H19ClN4O3S2, CAS 895104-56-0$

2-({9-[(4-Chlorophenyl)methyl]-8,8-dioxo-8lambda6-thia-3,5,9-triazatricyclo[8.4.0.0^{2,7}]tetradeca-1(14),2(7),3,5,10,12-hexaen-4-yl}sulfanyl)-N-phenylacetamide

CAS 895104-56-0C₂₅H₁₉ClN₄O₃S₂

$2-({9-Benzyl-8,8-dioxo-8lambda6-thia-3,5,9-triazatricyclo[8.4.0.0^{2,7}]tetradeca-1(14),2(7),3,5,10,12-hexaen-4-yl}sulfanyl)-N-(4-ethylphenyl)acetamide chemical structure, C27H24N4O3S2, CAS 892292-91-0$

2-({9-Benzyl-8,8-dioxo-8lambda6-thia-3,5,9-triazatricyclo[8.4.0.0^{2,7}]tetradeca-1(14),2(7),3,5,10,12-hexaen-4-yl}sulfanyl)-N-(4-ethylphenyl)acetamide

CAS 892292-91-0C₂₇H₂₄N₄O₃S₂

2-((6-(3-Methoxybenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)-N-phenylacetamide chemical structure, C26H22N4O4S2, CAS 892312-23-1

2-((6-(3-Methoxybenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)-N-phenylacetamide

CAS 892312-23-1C₂₆H₂₂N₄O₄S₂

2-((6-(3-Methoxybenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)-N-(o-tolyl)acetamide chemical structure, C27H24N4O4S2, CAS 892312-30-0

2-((6-(3-Methoxybenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)-N-(o-tolyl)acetamide

CAS 892312-30-0C₂₇H₂₄N₄O₄S₂

2-{[6-(3-Methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}-N-(4-methylphenyl)acetamide chemical structure, C27H24N4O4S2, CAS 892312-44-6

2-{[6-(3-Methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}-N-(4-methylphenyl)acetamide

CAS 892312-44-6C₂₇H₂₄N₄O₄S₂

2-{[6-(3-Methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide chemical structure, C27H24N4O5S2, CAS 892312-51-5

2-{[6-(3-Methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide

CAS 892312-51-5C₂₇H₂₄N₄O₅S₂

2-{[6-(3-Methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}-N-(3-methoxyphenyl)acetamide chemical structure, C27H24N4O5S2, CAS 892312-58-2

2-{[6-(3-Methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}-N-(3-methoxyphenyl)acetamide

CAS 892312-58-2C₂₇H₂₄N₄O₅S₂

2-{[6-(3-Methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}-N-(4-methoxyphenyl)acetamide chemical structure, C27H24N4O5S2, CAS 892312-65-1

2-{[6-(3-Methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}-N-(4-methoxyphenyl)acetamide

CAS 892312-65-1C₂₇H₂₄N₄O₅S₂

N-(2-Fluorophenyl)-2-((6-(3-methoxybenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide chemical structure, C26H21FN4O4S2, CAS 892312-93-5

N-(2-Fluorophenyl)-2-((6-(3-methoxybenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide

CAS 892312-93-5C₂₆H₂₁FN₄O₄S₂

N-(3-Fluorophenyl)-2-{[6-(3-methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}acetamide chemical structure, C26H21FN4O4S2, CAS 892313-00-7

N-(3-Fluorophenyl)-2-{[6-(3-methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}acetamide

CAS 892313-00-7C₂₆H₂₁FN₄O₄S₂

N-(3,4-Dimethylphenyl)-2-((6-(3-methoxybenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide chemical structure, C28H26N4O4S2, CAS 892313-07-4

N-(3,4-Dimethylphenyl)-2-((6-(3-methoxybenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide

CAS 892313-07-4C₂₈H₂₆N₄O₄S₂

N-(2,5-Dimethylphenyl)-2-{[6-(3-methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}acetamide chemical structure, C28H26N4O4S2, CAS 892313-14-3

N-(2,5-Dimethylphenyl)-2-{[6-(3-methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}acetamide

CAS 892313-14-3C₂₈H₂₆N₄O₄S₂

N-(2,3-Dimethylphenyl)-2-{[6-(3-methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}acetamide chemical structure, C28H26N4O4S2, CAS 892313-21-2

N-(2,3-Dimethylphenyl)-2-{[6-(3-methoxybenzyl)-5,5-dioxido-6H-pyrimido[5,4-c][2,1]benzothiazin-2-yl]sulfanyl}acetamide

CAS 892313-21-2C₂₈H₂₆N₄O₄S₂

N-(4-Fluorophenyl)-2-((6-(3-methoxybenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide chemical structure, C26H21FN4O4S2, CAS 899548-07-3

N-(4-Fluorophenyl)-2-((6-(3-methoxybenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide

CAS 899548-07-3C₂₆H₂₁FN₄O₄S₂

2-((6-(4-Methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)-N-(m-tolyl)acetamide chemical structure, C27H24N4O3S2, CAS 1115516-28-3

2-((6-(4-Methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)-N-(m-tolyl)acetamide

CAS 1115516-28-3C₂₇H₂₄N₄O₃S₂

2-((6-(4-Methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)-N-(p-tolyl)acetamide chemical structure, C27H24N4O3S2, CAS 1115408-57-5

2-((6-(4-Methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)-N-(p-tolyl)acetamide

CAS 1115408-57-5C₂₇H₂₄N₄O₃S₂

N-(3-Methoxyphenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide chemical structure, C27H24N4O4S2, CAS 1115570-27-8

N-(3-Methoxyphenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide

CAS 1115570-27-8C₂₇H₂₄N₄O₄S₂

N-(3-Chlorophenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide chemical structure, C26H21ClN4O3S2, CAS 1115408-58-6

N-(3-Chlorophenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide

CAS 1115408-58-6C₂₆H₂₁ClN₄O₃S₂

N-(4-Chlorophenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide chemical structure, C26H21ClN4O3S2, CAS 1115570-29-0

N-(4-Chlorophenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide

CAS 1115570-29-0C₂₆H₂₁ClN₄O₃S₂

N-(2-Fluorophenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide chemical structure, C26H21FN4O3S2, CAS 1115311-80-2

N-(2-Fluorophenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide

CAS 1115311-80-2C₂₆H₂₁FN₄O₃S₂

N-(2,5-Dimethylphenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide chemical structure, C28H26N4O3S2, CAS 1115408-60-0

N-(2,5-Dimethylphenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide

CAS 1115408-60-0C₂₈H₂₆N₄O₃S₂

N-(3-Fluoro-4-methylphenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide chemical structure, C27H23FN4O3S2, CAS 1115570-33-6

N-(3-Fluoro-4-methylphenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide

CAS 1115570-33-6C₂₇H₂₃FN₄O₃S₂

N-(2,5-Difluorophenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide chemical structure, C26H20F2N4O3S2, CAS 1115570-37-0

N-(2,5-Difluorophenyl)-2-((6-(4-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)acetamide

CAS 1115570-37-0C₂₆H₂₀F₂N₄O₃S₂