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Murcko scaffold

Ring system with 4 rings and 27 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
13
With full pages
2
Scaffold SMILES

O=C(NCCN1CCOCC1)c1cc(-c2ccccc2)nc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCN1CCOCC1)c1cc(-c2ccccc2)nc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

2-(3,4-Dichlorophenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide chemical structure, C22H21Cl2N3O2, CAS 544427-96-5
2-(3,4-Dichlorophenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide
CAS 544427-96-5C22H21Cl2N3O2
2-(2,4-Dichlorophenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide chemical structure, C22H21Cl2N3O2, CAS 546082-20-6
2-(2,4-Dichlorophenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide
CAS 546082-20-6C22H21Cl2N3O2
2-(4-Methylphenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide chemical structure, C23H25N3O2, CAS 313703-81-0
2-(4-Methylphenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide
CAS 313703-81-0C23H25N3O2
2-(2,4-Dimethoxyphenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide chemical structure, C24H27N3O4, CAS 303135-00-4
2-(2,4-Dimethoxyphenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide
CAS 303135-00-4C24H27N3O4
2-(3-Bromophenyl)-N-[2-(morpholin-4-yl)ethyl]quinoline-4-carboxamide chemical structure, C22H22BrN3O2, CAS 353476-79-6
2-(3-Bromophenyl)-N-[2-(morpholin-4-yl)ethyl]quinoline-4-carboxamide
CAS 353476-79-6C22H22BrN3O2
2-(2-Chlorophenyl)-8-methyl-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide chemical structure, C23H24ClN3O2, CAS 713121-32-5
2-(2-Chlorophenyl)-8-methyl-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide
CAS 713121-32-5C23H24ClN3O2
RefChem:381692 chemical structure, C25H29N3O2, CAS 6132-10-1
RefChem:381692
CAS 6132-10-1C25H29N3O2
N-(2-Morpholin-4-ylethyl)-2-(3-propoxyphenyl)quinoline-4-carboxamide chemical structure, C25H29N3O3, CAS 444906-38-1
N-(2-Morpholin-4-ylethyl)-2-(3-propoxyphenyl)quinoline-4-carboxamide
CAS 444906-38-1C25H29N3O3
2-(4-Ethylphenyl)-6-methyl-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide chemical structure, C25H29N3O2, CAS 588697-28-3
2-(4-Ethylphenyl)-6-methyl-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide
CAS 588697-28-3C25H29N3O2
3-Methyl-2-(4-methylphenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide chemical structure, C24H27N3O2, CAS 543709-02-0
3-Methyl-2-(4-methylphenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide
CAS 543709-02-0C24H27N3O2
6-Bromo-2-(4-butylphenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide chemical structure, C26H30BrN3O2, CAS 438211-11-1
6-Bromo-2-(4-butylphenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide
CAS 438211-11-1C26H30BrN3O2
6-Chloro-2-(2,4-dimethylphenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide chemical structure, C24H26ClN3O2, CAS 588683-60-7
6-Chloro-2-(2,4-dimethylphenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide
CAS 588683-60-7C24H26ClN3O2
2-(3,4-Dimethylphenyl)-8-methyl-N-[2-(morpholin-4-yl)ethyl]quinoline-4-carboxamide chemical structure, C25H29N3O2, CAS 669725-96-6
2-(3,4-Dimethylphenyl)-8-methyl-N-[2-(morpholin-4-yl)ethyl]quinoline-4-carboxamide
CAS 669725-96-6C25H29N3O2