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Murcko scaffold

N-(2-Phenylethyl)-2-(2-pyridinyl)-4-quinolinecarboxamide scaffold

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
8
With full pages
2
Scaffold SMILES

O=C(NCCc1ccccc1)c1cc(-c2ccccn2)nc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(2-Phenylethyl)-2-(2-pyridinyl)-4-quinolinecarboxamide page
Murcko scaffold O=C(NCCc1ccccc1)c1cc(-c2ccccn2)nc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

6-Bromo-N-[2-(2-methoxyphenyl)ethyl]-2-pyridin-2-ylquinoline-4-carboxamide chemical structure, C24H20BrN3O2, CAS 713119-98-3
6-Bromo-N-[2-(2-methoxyphenyl)ethyl]-2-pyridin-2-ylquinoline-4-carboxamide
CAS 713119-98-3C24H20BrN3O2
8-Chloro-N-[2-(3,4-dimethoxyphenyl)ethyl]-2-(2-pyridinyl)-4-quinolinecarboxamide chemical structure, C25H22ClN3O3, CAS 713117-97-6
8-Chloro-N-[2-(3,4-dimethoxyphenyl)ethyl]-2-(2-pyridinyl)-4-quinolinecarboxamide
CAS 713117-97-6C25H22ClN3O3
N-[2-(4-Methoxyphenyl)ethyl]-2-(pyridin-2-yl)quinoline-4-carboxamide chemical structure, C24H21N3O2, CAS 438018-75-8
N-[2-(4-Methoxyphenyl)ethyl]-2-(pyridin-2-yl)quinoline-4-carboxamide
CAS 438018-75-8C24H21N3O2
N-(2-Phenylethyl)-2-(2-pyridinyl)-4-quinolinecarboxamide chemical structure, C23H19N3O, CAS 690217-84-6
N-(2-Phenylethyl)-2-(2-pyridinyl)-4-quinolinecarboxamide
CAS 690217-84-6C23H19N3O
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-pyridin-2-ylquinoline-4-carboxamide chemical structure, C25H23N3O3, CAS 879918-95-3
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-pyridin-2-ylquinoline-4-carboxamide
CAS 879918-95-3C25H23N3O3
2-(Pyridin-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]quinoline-4-carboxamide chemical structure, C23H20N4O3S, CAS 1013262-26-4
2-(Pyridin-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]quinoline-4-carboxamide
CAS 1013262-26-4C23H20N4O3S
N-(4-Fluorophenethyl)-2-(2-pyridyl)-4-quinolinecarboxamide chemical structure, C23H18FN3O, CAS 1144457-43-1
N-(4-Fluorophenethyl)-2-(2-pyridyl)-4-quinolinecarboxamide
CAS 1144457-43-1C23H18FN3O
N-(2-Hydroxy-2-phenylethyl)-2-(pyridin-2-yl)quinoline-4-carboxamide chemical structure, C23H19N3O2, CAS 1144428-70-5
N-(2-Hydroxy-2-phenylethyl)-2-(pyridin-2-yl)quinoline-4-carboxamide
CAS 1144428-70-5C23H19N3O2