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Murcko scaffold

4-(Oxolan-2-yl)-1H-pyrazole scaffold

93 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
93
With full pages
14
Scaffold SMILES

c1n[nH]cc1C1CCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Oxolan-2-yl)-1H-pyrazole page
Murcko scaffold c1n[nH]cc1C1CCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 93 chemicals

4-[(2S,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-1H-pyrazole-5-carboxylic acid methyl ester chemical structure, C10H14N2O6, CAS 50866-58-5
4-[(2S,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-1H-pyrazole-5-carboxylic acid methyl ester
CAS 50866-58-5C10H14N2O6
[2-(1-Methyl-1H-pyrazol-4-yl)oxolan-3-yl]methanamine chemical structure, C9H15N3O, CAS 1423034-27-8
[2-(1-Methyl-1H-pyrazol-4-yl)oxolan-3-yl]methanamine
CAS 1423034-27-8C9H15N3O
[2-(Trimethyl-1H-pyrazol-4-yl)oxolan-3-yl]methanamine chemical structure, C11H19N3O, CAS 1384427-61-5
[2-(Trimethyl-1H-pyrazol-4-yl)oxolan-3-yl]methanamine
CAS 1384427-61-5C11H19N3O
[2-(1-Ethyl-1H-pyrazol-4-yl)oxolan-3-yl]methanamine chemical structure, C10H17N3O, CAS 1423034-61-0
[2-(1-Ethyl-1H-pyrazol-4-yl)oxolan-3-yl]methanamine
CAS 1423034-61-0C10H17N3O
[2-(1-Methyl-1H-pyrazol-4-yl)oxolan-3-yl]methanol chemical structure, C9H14N2O2, CAS 1506625-37-1
[2-(1-Methyl-1H-pyrazol-4-yl)oxolan-3-yl]methanol
CAS 1506625-37-1C9H14N2O2
2-(1-Methyl-1H-pyrazol-4-yl)oxolan-3-amine chemical structure, C8H13N3O, CAS 1520920-04-0
2-(1-Methyl-1H-pyrazol-4-yl)oxolan-3-amine
CAS 1520920-04-0C8H13N3O
2-(1-Methyl-1H-pyrazol-4-yl)oxolane-3-carboxylic acid chemical structure, C9H12N2O3, CAS 1540944-58-8
2-(1-Methyl-1H-pyrazol-4-yl)oxolane-3-carboxylic acid
CAS 1540944-58-8C9H12N2O3
2-(1,5-Dimethyl-1H-pyrazol-4-yl)oxolane-3-carboxylic acid chemical structure, C10H14N2O3, CAS 1526713-39-2
2-(1,5-Dimethyl-1H-pyrazol-4-yl)oxolane-3-carboxylic acid
CAS 1526713-39-2C10H14N2O3
2-(1,5-Dimethyl-1H-pyrazol-4-yl)oxolan-3-amine chemical structure, C9H15N3O, CAS 1542116-43-7
2-(1,5-Dimethyl-1H-pyrazol-4-yl)oxolan-3-amine
CAS 1542116-43-7C9H15N3O
2-(1,3-Dimethyl-1H-pyrazol-4-yl)oxolan-3-amine chemical structure, C9H15N3O, CAS 1556676-40-4
2-(1,3-Dimethyl-1H-pyrazol-4-yl)oxolan-3-amine
CAS 1556676-40-4C9H15N3O
(2R,3S)-2-(1-Ethyl-1H-pyrazol-4-yl)oxolan-3-amine dihydrochloride chemical structure, C9H17Cl2N3O, CAS 1807891-15-1
(2R,3S)-2-(1-Ethyl-1H-pyrazol-4-yl)oxolan-3-amine dihydrochloride
CAS 1807891-15-1C9H17Cl2N3O
(2R,3S)-2-(1-Ethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-amine chemical structure, C9H15N3O, CAS 1820579-93-8
(2R,3S)-2-(1-Ethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-amine
CAS 1820579-93-8C9H15N3O
(2S,3S)-2-(1-Methyl-1H-pyrazol-4-yl)oxolane-3-carboxylic acid chemical structure, C9H12N2O3, CAS 1820575-30-1
(2S,3S)-2-(1-Methyl-1H-pyrazol-4-yl)oxolane-3-carboxylic acid
CAS 1820575-30-1C9H12N2O3
(2S,3S)-2-(1-Ethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-carboxylic acid chemical structure, C10H14N2O3, CAS 1820574-45-5
(2S,3S)-2-(1-Ethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-carboxylic acid
CAS 1820574-45-5C10H14N2O3
(2S,3S)-2-(1,5-Dimethyl-1H-pyrazol-4-yl)oxolane-3-carboxylic acid chemical structure, C10H14N2O3, CAS 1820580-50-4
(2S,3S)-2-(1,5-Dimethyl-1H-pyrazol-4-yl)oxolane-3-carboxylic acid
CAS 1820580-50-4C10H14N2O3
(2R,3S)-2-(1-Methyl-1H-pyrazol-4-yl)oxolan-3-amine dihydrochloride chemical structure, C8H15Cl2N3O, CAS 1807941-18-9
(2R,3S)-2-(1-Methyl-1H-pyrazol-4-yl)oxolan-3-amine dihydrochloride
CAS 1807941-18-9C8H15Cl2N3O
(2R,3S)-2-(1-Methyl-1H-pyrazol-4-yl)tetrahydrofuran-3-amine chemical structure, C8H13N3O, CAS 1808069-50-2
(2R,3S)-2-(1-Methyl-1H-pyrazol-4-yl)tetrahydrofuran-3-amine
CAS 1808069-50-2C8H13N3O
(2R,3S)-2-(1,5-Dimethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-amine dihydrochloride chemical structure, C9H17Cl2N3O, CAS 1808313-99-6
(2R,3S)-2-(1,5-Dimethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-amine dihydrochloride
CAS 1808313-99-6C9H17Cl2N3O
(2R,3S)-2-(1,5-Dimethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-amine chemical structure, C9H15N3O, CAS 1808313-98-5
(2R,3S)-2-(1,5-Dimethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-amine
CAS 1808313-98-5C9H15N3O
(2S,3S)-2-(1,3,5-Trimethyl-1H-pyrazol-4-yl)oxolane-3-carboxylic acid chemical structure, C11H16N2O3, CAS 1808323-72-9
(2S,3S)-2-(1,3,5-Trimethyl-1H-pyrazol-4-yl)oxolane-3-carboxylic acid
CAS 1808323-72-9C11H16N2O3
(2R,3S)-2-(Trimethyl-1H-pyrazol-4-yl)oxolan-3-amine dihydrochloride chemical structure, C10H19Cl2N3O, CAS 1808654-34-3
(2R,3S)-2-(Trimethyl-1H-pyrazol-4-yl)oxolan-3-amine dihydrochloride
CAS 1808654-34-3C10H19Cl2N3O
(2R,3S)-2-(1,3,5-Trimethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-amine chemical structure, C10H17N3O, CAS 1808068-62-3
(2R,3S)-2-(1,3,5-Trimethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-amine
CAS 1808068-62-3C10H17N3O
((2S,3R)-2-(1-Ethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-yl)methanamine chemical structure, C10H17N3O, CAS 1820576-33-7
((2S,3R)-2-(1-Ethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-yl)methanamine
CAS 1820576-33-7C10H17N3O
(2S,3S)-2-[1-(Propan-2-yl)-1H-pyrazol-4-yl]oxolane-3-carboxylic acid chemical structure, C11H16N2O3, CAS 1820569-83-2
(2S,3S)-2-[1-(Propan-2-yl)-1H-pyrazol-4-yl]oxolane-3-carboxylic acid
CAS 1820569-83-2C11H16N2O3