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Murcko scaffold

Ring system with 2 rings and 12 atoms

43 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
43
With full pages
7
Scaffold SMILES

c1ccc(Sc2ncc[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Sc2ncc[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

4-[(1-Methyl-1H-imidazol-2-yl)thio]aniline chemical structure, C10H11N3S, CAS 96591-94-5
4-[(1-Methyl-1H-imidazol-2-yl)thio]aniline
CAS 96591-94-5C10H11N3S
4-[(1-Methyl-1H-imidazol-2-yl)sulfanyl]-3-nitrobenzaldehyde chemical structure, C11H9N3O3S, CAS 311322-41-5
4-[(1-Methyl-1H-imidazol-2-yl)sulfanyl]-3-nitrobenzaldehyde
CAS 311322-41-5C11H9N3O3S
1-Methyl-2-(phenylsulfanyl)-1H-imidazole-5-carbaldehyde chemical structure, C11H10N2OS, CAS 460990-29-8
1-Methyl-2-(phenylsulfanyl)-1H-imidazole-5-carbaldehyde
CAS 460990-29-8C11H10N2OS
2-(2-Chloro-4-nitrophenyl)sulfanyl-1-methylimidazole chemical structure, C10H8ClN3O2S, CAS 133303-87-4
2-(2-Chloro-4-nitrophenyl)sulfanyl-1-methylimidazole
CAS 133303-87-4C10H8ClN3O2S
1-Methyl-2-(2-nitrophenyl)sulfanylimidazole chemical structure, C10H9N3O2S, CAS 133303-52-3
1-Methyl-2-(2-nitrophenyl)sulfanylimidazole
CAS 133303-52-3C10H9N3O2S
Methyl 2-((2,6-dinitro-4-(trifluoromethyl)phenyl)sulfanyl)-1-methyl-1H-imidazole-5-carboxylate chemical structure, C13H9F3N4O6S, CAS 339278-20-5
Methyl 2-((2,6-dinitro-4-(trifluoromethyl)phenyl)sulfanyl)-1-methyl-1H-imidazole-5-carboxylate
CAS 339278-20-5C13H9F3N4O6S
1H-Imidazole-1-sulfonamide, N,N-dimethyl-2-(phenylthio)- chemical structure, C11H13N3O2S2, CAS 123914-19-2
1H-Imidazole-1-sulfonamide, N,N-dimethyl-2-(phenylthio)-
CAS 123914-19-2C11H13N3O2S2
1H-Imidazole, 2-[(4-chloro-2-nitrophenyl)thio]- chemical structure, C9H6ClN3O2S, CAS 88251-64-3
1H-Imidazole, 2-[(4-chloro-2-nitrophenyl)thio]-
CAS 88251-64-3C9H6ClN3O2S
1H-Imidazole, 2-[[2-nitro-4-(trifluoromethyl)phenyl]thio]- chemical structure, C10H6F3N3O2S, CAS 88251-66-5
1H-Imidazole, 2-[[2-nitro-4-(trifluoromethyl)phenyl]thio]-
CAS 88251-66-5C10H6F3N3O2S
Benzenamine, 5-chloro-2-(1H-imidazol-2-ylthio)- chemical structure, C9H8ClN3S, CAS 88251-69-8
Benzenamine, 5-chloro-2-(1H-imidazol-2-ylthio)-
CAS 88251-69-8C9H8ClN3S
Benzenamine, 2-(1H-imidazol-2-ylthio)-5-(trifluoromethyl)- chemical structure, C10H8F3N3S, CAS 88251-71-2
Benzenamine, 2-(1H-imidazol-2-ylthio)-5-(trifluoromethyl)-
CAS 88251-71-2C10H8F3N3S
4-(1-Methylimidazol-2-yl)sulfanyl-3-nitrobenzamide chemical structure, C11H10N4O3S, CAS 852294-69-0
4-(1-Methylimidazol-2-yl)sulfanyl-3-nitrobenzamide
CAS 852294-69-0C11H10N4O3S
2-((1-Methyl-1H-imidazol-2-yl)thio)-5-nitrobenzonitrile chemical structure, C11H8N4O2S, CAS 849053-97-0
2-((1-Methyl-1H-imidazol-2-yl)thio)-5-nitrobenzonitrile
CAS 849053-97-0C11H8N4O2S
2-Cyano-3-{4-[(1-methyl-1H-imidazol-2-yl)sulfanyl]-3-nitrophenyl}prop-2-enamide chemical structure, C14H11N5O3S, CAS 852902-11-5
2-Cyano-3-{4-[(1-methyl-1H-imidazol-2-yl)sulfanyl]-3-nitrophenyl}prop-2-enamide
CAS 852902-11-5C14H11N5O3S
1-Methyl-2-phenylsulfanyl-1H-imidazole chemical structure, C10H10N2S, CAS 79487-95-9
1-Methyl-2-phenylsulfanyl-1H-imidazole
CAS 79487-95-9C10H10N2S
Methyl 2-[3-(methoxymethyl)-2-(phenylsulfanyl)imidazol-4-yl]-2-oxoacetate chemical structure, C14H14N2O4S, CAS 219817-91-1
Methyl 2-[3-(methoxymethyl)-2-(phenylsulfanyl)imidazol-4-yl]-2-oxoacetate
CAS 219817-91-1C14H14N2O4S
1H-Imidazole, 1-(methoxymethyl)-2-(phenylthio)- chemical structure, C11H12N2OS, CAS 67319-05-5
1H-Imidazole, 1-(methoxymethyl)-2-(phenylthio)-
CAS 67319-05-5C11H12N2OS
2-(Phenylthio)-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-imidazole chemical structure, C15H22N2OSSi, CAS 153172-35-1
2-(Phenylthio)-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-imidazole
CAS 153172-35-1C15H22N2OSSi
3-Chloro-4-(1-methyl-1H-imidazol-2-ylsulfanyl)phenylamine chemical structure, C10H10ClN3S, CAS 133303-88-5
3-Chloro-4-(1-methyl-1H-imidazol-2-ylsulfanyl)phenylamine
CAS 133303-88-5C10H10ClN3S
2-[(2-Nitrophenyl)sulfanyl]-1H-imidazole chemical structure, C9H7N3O2S, CAS 81382-49-2
2-[(2-Nitrophenyl)sulfanyl]-1H-imidazole
CAS 81382-49-2C9H7N3O2S
2-((1H-Imidazol-2-yl)thio)aniline chemical structure, C9H9N3S, CAS 81382-50-5
2-((1H-Imidazol-2-yl)thio)aniline
CAS 81382-50-5C9H9N3S
2-[(4-Fluoro-2-nitrophenyl)sulfanyl]-1H-imidazole chemical structure, C9H6FN3O2S, CAS 88251-65-4
2-[(4-Fluoro-2-nitrophenyl)sulfanyl]-1H-imidazole
CAS 88251-65-4C9H6FN3O2S
2-[(4-Methoxy-2-nitrophenyl)sulfanyl]-1H-imidazole chemical structure, C10H9N3O3S, CAS 88251-67-6
2-[(4-Methoxy-2-nitrophenyl)sulfanyl]-1H-imidazole
CAS 88251-67-6C10H9N3O3S
5-Methyl-2-[(2-nitrophenyl)sulfanyl]-1H-imidazole chemical structure, C10H9N3O2S, CAS 88251-68-7
5-Methyl-2-[(2-nitrophenyl)sulfanyl]-1H-imidazole
CAS 88251-68-7C10H9N3O2S