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Murcko scaffold

Ring system with 2 rings and 15 atoms

116 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
116
With full pages
7
Scaffold SMILES

c1ccc(CCNc2ccncn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCNc2ccncn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 116 chemicals

Pyrimidine, 5-amino-6-chloro-4-(phenethylamino)- chemical structure, C12H13ClN4, CAS 73840-54-7
Pyrimidine, 5-amino-6-chloro-4-(phenethylamino)-
CAS 73840-54-7C12H13ClN4
4-{2-[(2-Amino-6-chloropyrimidin-4-yl)amino]ethyl}phenol chemical structure, C12H13ClN4O, CAS 122862-31-1
4-{2-[(2-Amino-6-chloropyrimidin-4-yl)amino]ethyl}phenol
CAS 122862-31-1C12H13ClN4O
N-(2-Amino-6-chloro-4-pyrimidinyl)-N-phenethylamine chemical structure, C12H13ClN4, CAS 122862-39-9
N-(2-Amino-6-chloro-4-pyrimidinyl)-N-phenethylamine
CAS 122862-39-9C12H13ClN4
4-[2-[(5-Amino-6-chloropyrimidin-4-yl)amino]ethyl]phenol chemical structure, C12H13ClN4O, CAS 27174-58-9
4-[2-[(5-Amino-6-chloropyrimidin-4-yl)amino]ethyl]phenol
CAS 27174-58-9C12H13ClN4O
N-[2-(3,4-Dimethoxyphenyl)ethyl]-5-nitropyrimidine-4,6-diamine chemical structure, C14H17N5O4, CAS 450344-96-4
N-[2-(3,4-Dimethoxyphenyl)ethyl]-5-nitropyrimidine-4,6-diamine
CAS 450344-96-4C14H17N5O4
5-Nitro-N-(2-phenylethyl)pyrimidine-4,6-diamine chemical structure, C12H13N5O2, CAS 100115-58-0
5-Nitro-N-(2-phenylethyl)pyrimidine-4,6-diamine
CAS 100115-58-0C12H13N5O2
4-(2-((6-Amino-5-nitropyrimidin-4-yl)amino)ethyl)benzenesulfonamide chemical structure, C12H14N6O4S, CAS 306290-96-0
4-(2-((6-Amino-5-nitropyrimidin-4-yl)amino)ethyl)benzenesulfonamide
CAS 306290-96-0C12H14N6O4S
N4-(4-chlorophenethyl)-5-nitropyrimidine-4,6-diamine chemical structure, C12H12ClN5O2, CAS 450344-95-3
N4-(4-chlorophenethyl)-5-nitropyrimidine-4,6-diamine
CAS 450344-95-3C12H12ClN5O2
Flufenerim chemical structure, C15H14ClF4N3O, CAS 170015-32-4
Flufenerim
CAS 170015-32-4C15H14ClF4N3O
2-((2-Amino-6-chloropyrimidin-4-yl)amino)-1-phenylethan-1-ol chemical structure, C12H13ClN4O, CAS 122862-56-0
2-((2-Amino-6-chloropyrimidin-4-yl)amino)-1-phenylethan-1-ol
CAS 122862-56-0C12H13ClN4O
2-Chloro-N-(2-phenylethyl)-4-pyrimidinamine chemical structure, C12H12ClN3, CAS 32016-20-9
2-Chloro-N-(2-phenylethyl)-4-pyrimidinamine
CAS 32016-20-9C12H12ClN3
6-Chloro-N4-(3,4-dimethoxyphenethyl)pyrimidine-4,5-diamine chemical structure, C14H17ClN4O2, CAS 27188-91-6
6-Chloro-N4-(3,4-dimethoxyphenethyl)pyrimidine-4,5-diamine
CAS 27188-91-6C14H17ClN4O2
N4-(3-Methylbutyl)-5-nitro-N6-(2-phenylethyl)-4,6-pyrimidinediamine chemical structure, C17H23N5O2, CAS 883518-61-4
N4-(3-Methylbutyl)-5-nitro-N6-(2-phenylethyl)-4,6-pyrimidinediamine
CAS 883518-61-4C17H23N5O2
2-[(2-Aminopyrimidin-4-yl)amino]-1-phenyl-ethanol chemical structure, C12H15ClN4O, CAS 3603-50-7
2-[(2-Aminopyrimidin-4-yl)amino]-1-phenyl-ethanol
CAS 3603-50-7C12H15ClN4O
2-[(2-Methylsulfanylpyrimidin-4-yl)amino]-1-phenyl-ethanol chemical structure, C13H16ClN3OS, CAS 3610-56-8
2-[(2-Methylsulfanylpyrimidin-4-yl)amino]-1-phenyl-ethanol
CAS 3610-56-8C13H16ClN3OS
2-Chloro-N-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidin-4-amine chemical structure, C13H13ClFN3, CAS 885266-60-4
2-Chloro-N-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidin-4-amine
CAS 885266-60-4C13H13ClFN3
2-(Methylthio)-4-(phenethylamino)pyrimidine-5-carboxylic acid chemical structure, C14H15N3O2S, CAS 1065075-61-7
2-(Methylthio)-4-(phenethylamino)pyrimidine-5-carboxylic acid
CAS 1065075-61-7C14H15N3O2S
2-((2,6-Dimethylpyrimidin-4-yl)amino)-1-phenylethan-1-ol chemical structure, C14H17N3O, CAS 1179509-96-6
2-((2,6-Dimethylpyrimidin-4-yl)amino)-1-phenylethan-1-ol
CAS 1179509-96-6C14H17N3O
2,4-Pyrimidinediamine, 6-chloro-N4-[2-(3-methoxyphenyl)ethyl]- chemical structure, C13H15ClN4O, CAS 1375951-61-3
2,4-Pyrimidinediamine, 6-chloro-N4-[2-(3-methoxyphenyl)ethyl]-
CAS 1375951-61-3C13H15ClN4O
6-Chloro-2-methyl-N-phenethylpyrimidin-4-amine chemical structure, C13H14ClN3, CAS 1111849-62-7
6-Chloro-2-methyl-N-phenethylpyrimidin-4-amine
CAS 1111849-62-7C13H14ClN3
6-Chloro-N-(1-methyl-2-phenylethyl)-4-pyrimidinamine chemical structure, C13H14ClN3, CAS 27174-65-8
6-Chloro-N-(1-methyl-2-phenylethyl)-4-pyrimidinamine
CAS 27174-65-8C13H14ClN3
N2,N2-Dibutyl-6-methyl-N4-(2-phenylethyl)-2,4-pyrimidinediamine chemical structure, C21H32N4, CAS 53305-50-3
N2,N2-Dibutyl-6-methyl-N4-(2-phenylethyl)-2,4-pyrimidinediamine
CAS 53305-50-3C21H32N4
6-Chloro-N-[2-(2,4-dichlorophenyl)ethyl]-2-methoxy-4-pyrimidinamine chemical structure, C13H12Cl3N3O, CAS 1016644-41-9
6-Chloro-N-[2-(2,4-dichlorophenyl)ethyl]-2-methoxy-4-pyrimidinamine
CAS 1016644-41-9C13H12Cl3N3O
2-Methoxy-6-[2-(4-methoxy-phenyl)-ethylamino]-pyrimidine-4-carbaldehyde chemical structure, C15H17N3O3, CAS 885067-85-6
2-Methoxy-6-[2-(4-methoxy-phenyl)-ethylamino]-pyrimidine-4-carbaldehyde
CAS 885067-85-6C15H17N3O3