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Murcko scaffold

Ring system with 4 rings and 19 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
8
With full pages
1
Scaffold SMILES

c1ccc(-n2cnc3cc4c(cc32)OCCO4)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-n2cnc3cc4c(cc32)OCCO4)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2-Methyl-1-phenyl-6,7-dihydro-1H-[1,4]dioxino[2',3':4,5]benzo[1,2-d]imidazole chemical structure, C16H14N2O2, CAS 1500565-62-7
2-Methyl-1-phenyl-6,7-dihydro-1H-[1,4]dioxino[2',3':4,5]benzo[1,2-d]imidazole
CAS 1500565-62-7C16H14N2O2
2-{6-Phenyl-10,13-dioxa-4,6-diazatricyclo[7.4.0.0,3,7]trideca-1,3(7),4,8-tetraen-5-yl}ethan-1-amine chemical structure, C17H17N3O2, CAS 1512466-22-6
2-{6-Phenyl-10,13-dioxa-4,6-diazatricyclo[7.4.0.0,3,7]trideca-1,3(7),4,8-tetraen-5-yl}ethan-1-amine
CAS 1512466-22-6C17H17N3O2
2-(6-(3-(2-Methoxyethoxy)phenyl)-10,13-dioxa-4,6-diazatricyclo(7.4.0.0,3,7)trideca-1(9),2,4,7-tetraen-5-yl)ethan-1-amine dihydrochloride chemical structure, C20H25Cl2N3O4, CAS 2770359-50-5
2-(6-(3-(2-Methoxyethoxy)phenyl)-10,13-dioxa-4,6-diazatricyclo(7.4.0.0,3,7)trideca-1(9),2,4,7-tetraen-5-yl)ethan-1-amine dihydrochloride
CAS 2770359-50-5C20H25Cl2N3O4
2-{6-[3-(2-Methoxyethoxy)phenyl]-10,13-dioxa-4,6-diazatricyclo[7.4.0.0,3,7]trideca-1(9),2,4,7-tetraen-5-yl}ethan-1-amine chemical structure, C20H23N3O4, CAS 2770359-49-2
2-{6-[3-(2-Methoxyethoxy)phenyl]-10,13-dioxa-4,6-diazatricyclo[7.4.0.0,3,7]trideca-1(9),2,4,7-tetraen-5-yl}ethan-1-amine
CAS 2770359-49-2C20H23N3O4
2-{6-[3-(2-Methoxyethyl)phenyl]-10,13-dioxa-4,6-diazatricyclo[7.4.0.0,3,7]trideca-1,3(7),4,8-tetraen-5-yl}ethan-1-amine dihydrochloride chemical structure, C20H25Cl2N3O3, CAS 2803861-85-8
2-{6-[3-(2-Methoxyethyl)phenyl]-10,13-dioxa-4,6-diazatricyclo[7.4.0.0,3,7]trideca-1,3(7),4,8-tetraen-5-yl}ethan-1-amine dihydrochloride
CAS 2803861-85-8C20H25Cl2N3O3
2-{6-Phenyl-10,13-dioxa-4,6-diazatricyclo[7.4.0.0,3,7]trideca-1(9),2,4,7-tetraen-5-yl}ethan-1-aminedihydrochloride chemical structure, C17H19Cl2N3O2, CAS 2758005-29-5
2-{6-Phenyl-10,13-dioxa-4,6-diazatricyclo[7.4.0.0,3,7]trideca-1(9),2,4,7-tetraen-5-yl}ethan-1-aminedihydrochloride
CAS 2758005-29-5C17H19Cl2N3O2
2-[6-(3-Methoxyphenyl)-10,13-dioxa-4,6-diazatricyclo[7.4.0.0,3,7]trideca-1,3(7),4,8-tetraen-5-yl]ethan-1-amine dihydrochloride chemical structure, C18H21Cl2N3O3, CAS 2768326-82-3
2-[6-(3-Methoxyphenyl)-10,13-dioxa-4,6-diazatricyclo[7.4.0.0,3,7]trideca-1,3(7),4,8-tetraen-5-yl]ethan-1-amine dihydrochloride
CAS 2768326-82-3C18H21Cl2N3O3
2-[6-(3-Methoxyphenyl)-10,13-dioxa-4,6-diazatricyclo[7.4.0.0,3,7]trideca-1(9),2,4,7-tetraen-5-yl]ethan-1-amine chemical structure, C18H19N3O3, CAS 2768326-81-2
2-[6-(3-Methoxyphenyl)-10,13-dioxa-4,6-diazatricyclo[7.4.0.0,3,7]trideca-1(9),2,4,7-tetraen-5-yl]ethan-1-amine
CAS 2768326-81-2C18H19N3O3