CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 19 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
9
With full pages
4
Scaffold SMILES

c1ccc(-c2cnn3cc4c(nc23)CCCC4)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2cnn3cc4c(nc23)CCCC4)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

2-Methyl-3-phenyl-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline chemical structure, C18H16F3N3, CAS 428834-91-7
2-Methyl-3-phenyl-9-(trifluoromethyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline
CAS 428834-91-7C18H16F3N3
2-(2-((2-Methyl-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-yl)amino)ethoxy)ethanol chemical structure, C21H26N4O2, CAS 896810-48-3
2-(2-((2-Methyl-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-yl)amino)ethoxy)ethanol
CAS 896810-48-3C21H26N4O2
N-Isopropyl-2-methyl-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-amine chemical structure, C20H24N4, CAS 896855-41-7
N-Isopropyl-2-methyl-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-amine
CAS 896855-41-7C20H24N4
N-(2-Methoxyethyl)-2-methyl-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-amine chemical structure, C20H24N4O, CAS 899393-07-8
N-(2-Methoxyethyl)-2-methyl-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-amine
CAS 899393-07-8C20H24N4O
2-Methyl-N-(2-methylpropyl)-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-amine chemical structure, C21H26N4, CAS 900291-53-4
2-Methyl-N-(2-methylpropyl)-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-amine
CAS 900291-53-4C21H26N4
N',N'-Dimethyl-N-(2-methyl-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-yl)ethane-1,2-diamine chemical structure, C21H27N5, CAS 900276-25-7
N',N'-Dimethyl-N-(2-methyl-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-yl)ethane-1,2-diamine
CAS 900276-25-7C21H27N5
N1,N1-dimethyl-N3-(2-methyl-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-yl)propane-1,3-diamine chemical structure, C22H29N5, CAS 896078-59-4
N1,N1-dimethyl-N3-(2-methyl-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-yl)propane-1,3-diamine
CAS 896078-59-4C22H29N5
N-(sec-Butyl)-2-methyl-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-amine chemical structure, C21H26N4, CAS 899390-45-5
N-(sec-Butyl)-2-methyl-3-phenyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-amine
CAS 899390-45-5C21H26N4
9-Chloro-3-(4-methoxyphenyl)-2-methyl-5H,6H,7H,8H-pyrazolo[3,2-b]quinazoline chemical structure, C18H18ClN3O, CAS 1467609-62-6
9-Chloro-3-(4-methoxyphenyl)-2-methyl-5H,6H,7H,8H-pyrazolo[3,2-b]quinazoline
CAS 1467609-62-6C18H18ClN3O