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Murcko scaffold

1,2,3,6-Tetrahydropyridine scaffold

988 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
988
With full pages
111
Scaffold SMILES

C1=CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 1,2,3,6-Tetrahydropyridine page
Murcko scaffold C1=CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 529 to 576 of 988 chemicals

{2-[1-(3-Methylbut-2-en-1-yl)-1,2,3,6-tetrahydropyridin-4-yl]ethyl}amine dihydrochloride chemical structure, C12H24Cl2N2, CAS 1417349-90-6
{2-[1-(3-Methylbut-2-en-1-yl)-1,2,3,6-tetrahydropyridin-4-yl]ethyl}amine dihydrochloride
CAS 1417349-90-6C12H24Cl2N2
rac-(2S,6S)-2-Allyl-6-butyl-1,2,3,6-tetrahydropyridine hydrochloride chemical structure, C12H22ClN, CAS 1820580-25-3
rac-(2S,6S)-2-Allyl-6-butyl-1,2,3,6-tetrahydropyridine hydrochloride
CAS 1820580-25-3C12H22ClN
1(2H)-Pyridinecarboxylic acid, 2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-3,6-dihydro-, 1,1-dimethylethyl ester chemical structure, C17H33NO3Si, CAS 2055042-17-4
1(2H)-Pyridinecarboxylic acid, 2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-3,6-dihydro-, 1,1-dimethylethyl ester
CAS 2055042-17-4C17H33NO3Si
(2R,6R)-1,2,6-Trimethyl-1,2,3,6-tetrahydropyridine chemical structure, C8H15N, CAS 556005-77-7
(2R,6R)-1,2,6-Trimethyl-1,2,3,6-tetrahydropyridine
CAS 556005-77-7C8H15N
(2R,6S)-1,2,6-Trimethyl-1,2,3,6-tetrahydropyridine chemical structure, C8H15N, CAS 393531-22-1
(2R,6S)-1,2,6-Trimethyl-1,2,3,6-tetrahydropyridine
CAS 393531-22-1C8H15N
4-Methyl-5-propan-2-yl-1,2,3,6-tetrahydropyridine chemical structure, C9H17N, CAS 1373220-77-9
4-Methyl-5-propan-2-yl-1,2,3,6-tetrahydropyridine
CAS 1373220-77-9C9H17N
tert-Butyl 3-cyano-5,6-dihydropyridine-1(2H)-carboxylate chemical structure, C11H16N2O2, CAS 1239421-56-7
tert-Butyl 3-cyano-5,6-dihydropyridine-1(2H)-carboxylate
CAS 1239421-56-7C11H16N2O2
6-Methyl-4-(trifluoromethyl)-1,2,3,6-tetrahydropyridine hydrochloride chemical structure, C7H11ClF3N, CAS 1379350-66-9
6-Methyl-4-(trifluoromethyl)-1,2,3,6-tetrahydropyridine hydrochloride
CAS 1379350-66-9C7H11ClF3N
Pyridine, 1,2,5,6-tetrahydro-2-methyl-4-(trifluoromethyl)- chemical structure, C7H10F3N, CAS 1379379-96-0
Pyridine, 1,2,5,6-tetrahydro-2-methyl-4-(trifluoromethyl)-
CAS 1379379-96-0C7H10F3N
tert-Butyl 4-(2-aminoethyl)-1,2,3,6-tetrahydropyridine-1-carboxylate chemical structure, C12H22N2O2, CAS 1537603-47-6
tert-Butyl 4-(2-aminoethyl)-1,2,3,6-tetrahydropyridine-1-carboxylate
CAS 1537603-47-6C12H22N2O2
Methyl 2-(1,2,3,6-tetrahydropyridin-4-yl)acetate chemical structure, C8H13NO2, CAS 1783316-57-3
Methyl 2-(1,2,3,6-tetrahydropyridin-4-yl)acetate
CAS 1783316-57-3C8H13NO2
Methyl[(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)methyl]amine chemical structure, C8H16N2, CAS 1783316-62-0
Methyl[(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)methyl]amine
CAS 1783316-62-0C8H16N2
tert-Butyl 4-formyl-3,6-dihydropyridine-1(2H)-carboxylate chemical structure, C11H17NO3, CAS 1780737-34-9
tert-Butyl 4-formyl-3,6-dihydropyridine-1(2H)-carboxylate
CAS 1780737-34-9C11H17NO3
1(2H)-Pyridineethanamine, 3,6-dihydro-I(2)-(trifluoromethyl)- chemical structure, C8H13F3N2, CAS 1780951-20-3
1(2H)-Pyridineethanamine, 3,6-dihydro-I(2)-(trifluoromethyl)-
CAS 1780951-20-3C8H13F3N2
tert-Butyl 6-(hydroxymethyl)-1,2,3,6-tetrahydropyridine-1-carboxylate chemical structure, C11H19NO3, CAS 1824240-80-3
tert-Butyl 6-(hydroxymethyl)-1,2,3,6-tetrahydropyridine-1-carboxylate
CAS 1824240-80-3C11H19NO3
1(2H)-Pyridinecarboxylic acid, 3,6-dihydro-3-(hydroxymethyl)-, 1,1-dimethylethyl ester chemical structure, C11H19NO3, CAS 215725-60-3
1(2H)-Pyridinecarboxylic acid, 3,6-dihydro-3-(hydroxymethyl)-, 1,1-dimethylethyl ester
CAS 215725-60-3C11H19NO3
3,6-Dihydro-2H-pyridine-1-sulfonyl chloride chemical structure, C5H8ClNO2S, CAS 627887-44-9
3,6-Dihydro-2H-pyridine-1-sulfonyl chloride
CAS 627887-44-9C5H8ClNO2S
1-(2-Methylpropane-2-sulfinyl)-1,2,3,6-tetrahydropyridine chemical structure, C9H17NOS, CAS 643759-65-3
1-(2-Methylpropane-2-sulfinyl)-1,2,3,6-tetrahydropyridine
CAS 643759-65-3C9H17NOS
1-(5-Ethenyl-1,2,3,6-tetrahydropyridin-1-yl)-2,2,2-trifluoroethan-1-one chemical structure, C9H10F3NO, CAS 875138-36-6
1-(5-Ethenyl-1,2,3,6-tetrahydropyridin-1-yl)-2,2,2-trifluoroethan-1-one
CAS 875138-36-6C9H10F3NO
1-(3,6-Dihydro-2H-pyridin-1-yl)-propan-1-one chemical structure, C8H13NO, CAS 95524-72-4
1-(3,6-Dihydro-2H-pyridin-1-yl)-propan-1-one
CAS 95524-72-4C8H13NO
4-Bromo-1-methyl-1,2,3,6-tetrahydropyridine hydrobromide chemical structure, C6H11Br2N, CAS 1624261-20-6
4-Bromo-1-methyl-1,2,3,6-tetrahydropyridine hydrobromide
CAS 1624261-20-6C6H11Br2N
5,5-Dimethyl-4-trifluoromethanesulfonyloxy-5,6-dihydro-2H-pyridine-1,3-dicarboxylic acid 1-tert-butyl ester 3-methyl ester chemical structure, C15H22F3NO7S, CAS 851314-40-4
5,5-Dimethyl-4-trifluoromethanesulfonyloxy-5,6-dihydro-2H-pyridine-1,3-dicarboxylic acid 1-tert-butyl ester 3-methyl ester
CAS 851314-40-4C15H22F3NO7S
tert-Butyl 3-methyl-4-(trifluoromethylsulfonyloxy)-3,6-dihydro-2H-pyridine-1-carboxylate chemical structure, C12H18F3NO5S, CAS 1240971-20-3
tert-Butyl 3-methyl-4-(trifluoromethylsulfonyloxy)-3,6-dihydro-2H-pyridine-1-carboxylate
CAS 1240971-20-3C12H18F3NO5S
5-Bromo-1,2,3,6-tetrahydropyridine hydrochloride chemical structure, C5H9BrClN, CAS 1803581-46-5
5-Bromo-1,2,3,6-tetrahydropyridine hydrochloride
CAS 1803581-46-5C5H9BrClN