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Murcko scaffold

1,2,3,6-Tetrahydropyridine scaffold

988 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
988
With full pages
111
Scaffold SMILES

C1=CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 1,2,3,6-Tetrahydropyridine page
Murcko scaffold C1=CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 577 to 624 of 988 chemicals

[1-Methyl-1,2,5,6-tetrahydropyridine-3-yl]boronic acid chemical structure, C6H12BNO2, CAS 1443112-48-8
[1-Methyl-1,2,5,6-tetrahydropyridine-3-yl]boronic acid
CAS 1443112-48-8C6H12BNO2
2-(4-Methyl-1,2,3,6-tetrahydropyridin-1-yl)ethan-1-amine dihydrochloride chemical structure, C8H18Cl2N2, CAS 34975-14-9
2-(4-Methyl-1,2,3,6-tetrahydropyridin-1-yl)ethan-1-amine dihydrochloride
CAS 34975-14-9C8H18Cl2N2
4,5-Dimethyl-1,2,3,6-tetrahydropyridine hydrochloride chemical structure, C7H14ClN, CAS 1803582-71-9
4,5-Dimethyl-1,2,3,6-tetrahydropyridine hydrochloride
CAS 1803582-71-9C7H14ClN
3,5-Dimethyl-1,2,3,6-tetrahydropyridine hydrochloride chemical structure, C7H14ClN, CAS 1803581-89-6
3,5-Dimethyl-1,2,3,6-tetrahydropyridine hydrochloride
CAS 1803581-89-6C7H14ClN
5-Bromo-4-methyl-1,2,3,6-tetrahydropyridine hydrochloride chemical structure, C6H11BrClN, CAS 1803611-57-5
5-Bromo-4-methyl-1,2,3,6-tetrahydropyridine hydrochloride
CAS 1803611-57-5C6H11BrClN
5-Bromo-4-methyl-1,2,3,6-tetrahydropyridine chemical structure, C6H10BrN, CAS 1804130-08-2
5-Bromo-4-methyl-1,2,3,6-tetrahydropyridine
CAS 1804130-08-2C6H10BrN
Pipecolate derivative chemical structure, C15H25NO4, CAS 653589-42-5
Pipecolate derivative
CAS 653589-42-5C15H25NO4
1-(Methylsulfonyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid chemical structure, C7H11NO4S, CAS 1373247-05-2
1-(Methylsulfonyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid
CAS 1373247-05-2C7H11NO4S
1-(Ethylsulfonyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid chemical structure, C8H13NO4S, CAS 1373247-20-1
1-(Ethylsulfonyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid
CAS 1373247-20-1C8H13NO4S
1-(Isopropylsulfonyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid chemical structure, C9H15NO4S, CAS 1373247-78-9
1-(Isopropylsulfonyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid
CAS 1373247-78-9C9H15NO4S
1-(Propylsulfonyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid chemical structure, C9H15NO4S, CAS 1373247-13-2
1-(Propylsulfonyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid
CAS 1373247-13-2C9H15NO4S
1-Propionyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid chemical structure, C9H13NO3, CAS 1373247-61-0
1-Propionyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid
CAS 1373247-61-0C9H13NO3
1-Acetyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid chemical structure, C8H11NO3, CAS 1373246-99-1
1-Acetyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid
CAS 1373246-99-1C8H11NO3
1-Carbamoyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid chemical structure, C7H10N2O3, CAS 1373247-07-4
1-Carbamoyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid
CAS 1373247-07-4C7H10N2O3
2-(1-(tert-Butoxycarbonyl)-3,3-difluoro-1,2,3,6-tetrahydropyridin-4-yl)acetic acid chemical structure, C12H17F2NO4, CAS 1823257-61-9
2-(1-(tert-Butoxycarbonyl)-3,3-difluoro-1,2,3,6-tetrahydropyridin-4-yl)acetic acid
CAS 1823257-61-9C12H17F2NO4
tert-Butyl 4-(2-Ethoxy-2-oxoethyl)-5,5-difluoro-5,6-dihydropyridine-1(2H)-carboxylate chemical structure, C14H21F2NO4, CAS 1823275-22-4
tert-Butyl 4-(2-Ethoxy-2-oxoethyl)-5,5-difluoro-5,6-dihydropyridine-1(2H)-carboxylate
CAS 1823275-22-4C14H21F2NO4
4-Amino-1-nitroso-3,6-dihydro-2H-pyridine-5-carbonitrile chemical structure, C6H8N4O, CAS 15827-83-5
4-Amino-1-nitroso-3,6-dihydro-2H-pyridine-5-carbonitrile
CAS 15827-83-5C6H8N4O
Methyl 4-chloro-3-formyl-5,6-dihydropyridine-1(2H)-carboxylate chemical structure, C8H10ClNO3, CAS 1708250-56-9
Methyl 4-chloro-3-formyl-5,6-dihydropyridine-1(2H)-carboxylate
CAS 1708250-56-9C8H10ClNO3
tert-Butyl 4-(2-Ethoxy-1,1-difluoro-2-oxoethyl)-5,6-dihydropyridine-1(2H)-carboxylate chemical structure, C14H21F2NO4, CAS 1258637-70-5
tert-Butyl 4-(2-Ethoxy-1,1-difluoro-2-oxoethyl)-5,6-dihydropyridine-1(2H)-carboxylate
CAS 1258637-70-5C14H21F2NO4
1-tert-Butyl 3-ethyl 5,5-difluoro-5,6-dihydropyridine-1,3(2H)-dicarboxylate chemical structure, C13H19F2NO4, CAS 1823847-01-3
1-tert-Butyl 3-ethyl 5,5-difluoro-5,6-dihydropyridine-1,3(2H)-dicarboxylate
CAS 1823847-01-3C13H19F2NO4
1-O-(1-Chloroethyl) 5-O-methyl 3,6-dihydro-2H-pyridine-1,5-dicarboxylate chemical structure, C10H14ClNO4, CAS 92600-27-6
1-O-(1-Chloroethyl) 5-O-methyl 3,6-dihydro-2H-pyridine-1,5-dicarboxylate
CAS 92600-27-6C10H14ClNO4
tert-Butyl (2R,3S)-3-hydroxy-2-(hydroxymethyl)-3,6-dihydropyridine-1(2H)-carboxylate chemical structure, C11H19NO4, CAS 768387-44-6
tert-Butyl (2R,3S)-3-hydroxy-2-(hydroxymethyl)-3,6-dihydropyridine-1(2H)-carboxylate
CAS 768387-44-6C11H19NO4
1,1-Dimethylethyl 3-bromo-5,6-dihydro-4-[[(trifluoromethyl)sulfonyl]oxy]-1(2H)-pyridinecarboxylate chemical structure, C11H15BrF3NO5S, CAS 919491-05-7
1,1-Dimethylethyl 3-bromo-5,6-dihydro-4-[[(trifluoromethyl)sulfonyl]oxy]-1(2H)-pyridinecarboxylate
CAS 919491-05-7C11H15BrF3NO5S
tert-Butyl 4,5-dimethyl-1,2,3,6-tetrahydropyridine-1-carboxylate chemical structure, C12H21NO2, CAS 1211531-19-9
tert-Butyl 4,5-dimethyl-1,2,3,6-tetrahydropyridine-1-carboxylate
CAS 1211531-19-9C12H21NO2