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Murcko scaffold

1,2,3,6-Tetrahydropyridine scaffold

988 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
988
With full pages
111
Scaffold SMILES

C1=CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 1,2,3,6-Tetrahydropyridine page
Murcko scaffold C1=CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 625 to 672 of 988 chemicals

1-(tert-Butyl) 4-ethyl 5-methyl-3,6-dihydropyridine-1,4(2H)-dicarboxylate chemical structure, C14H23NO4, CAS 2932443-67-7
1-(tert-Butyl) 4-ethyl 5-methyl-3,6-dihydropyridine-1,4(2H)-dicarboxylate
CAS 2932443-67-7C14H23NO4
Ethyl 1,2,3,6-tetrahydropyridine-4-carboxylate hydrochloride chemical structure, C8H14ClNO2, CAS 1956319-74-6
Ethyl 1,2,3,6-tetrahydropyridine-4-carboxylate hydrochloride
CAS 1956319-74-6C8H14ClNO2
tert-Butyl 4-(hydroxymethyl)-5-methyl-3,6-dihydropyridine-1(2H)-carboxylate chemical structure, C12H21NO3, CAS 1883757-25-2
tert-Butyl 4-(hydroxymethyl)-5-methyl-3,6-dihydropyridine-1(2H)-carboxylate
CAS 1883757-25-2C12H21NO3
3-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)propanenitrile chemical structure, C9H14N2, CAS 1823322-85-5
3-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)propanenitrile
CAS 1823322-85-5C9H14N2
1-(tert-Butyl) 4-methyl 3,3-dimethyl-3,6-dihydropyridine-1,4(2H)-dicarboxylate chemical structure, C14H23NO4, CAS 1915004-56-6
1-(tert-Butyl) 4-methyl 3,3-dimethyl-3,6-dihydropyridine-1,4(2H)-dicarboxylate
CAS 1915004-56-6C14H23NO4
tert-Butyl 4-[2-(prop-2-enamido)ethyl]-1,2,3,6-tetrahydropyridine-1-carboxylate chemical structure, C15H24N2O3, CAS 2094408-10-1
tert-Butyl 4-[2-(prop-2-enamido)ethyl]-1,2,3,6-tetrahydropyridine-1-carboxylate
CAS 2094408-10-1C15H24N2O3
tert-Butyl 5-bromo-4-fluoro-5,6-dihydropyridine-1(2H)-carboxylate chemical structure, C10H15BrFNO2, CAS 1881331-83-4
tert-Butyl 5-bromo-4-fluoro-5,6-dihydropyridine-1(2H)-carboxylate
CAS 1881331-83-4C10H15BrFNO2
2-(5-Bromo-4-methyl-1,2,3,6-tetrahydropyridin-1-yl)-N-(1-cyano-1,2-dimethylpropyl)acetamide chemical structure, C14H22BrN3O, CAS 2094663-73-5
2-(5-Bromo-4-methyl-1,2,3,6-tetrahydropyridin-1-yl)-N-(1-cyano-1,2-dimethylpropyl)acetamide
CAS 2094663-73-5C14H22BrN3O
5-Chloro-1,2,3,6-tetrahydropyridine hydrochloride chemical structure, C5H9Cl2N, CAS 1909311-91-6
5-Chloro-1,2,3,6-tetrahydropyridine hydrochloride
CAS 1909311-91-6C5H9Cl2N
(1,2,3,6-Tetrahydropyridin-4-yl)phosphonic acid chemical structure, C5H10NO3P, CAS 464194-35-2
(1,2,3,6-Tetrahydropyridin-4-yl)phosphonic acid
CAS 464194-35-2C5H10NO3P
4-Bromo-1-propyl-1,2,3,6-tetrahydropyridine hydrochloride chemical structure, C8H15BrClN, CAS 1946021-36-8
4-Bromo-1-propyl-1,2,3,6-tetrahydropyridine hydrochloride
CAS 1946021-36-8C8H15BrClN
O1-tert-butyl O5-ethyl 4-hydroxy-3,6-dihydro-2H-pyridine-1,5-dicarboxylate chemical structure, C13H21NO5, CAS 206111-37-7
O1-tert-butyl O5-ethyl 4-hydroxy-3,6-dihydro-2H-pyridine-1,5-dicarboxylate
CAS 206111-37-7C13H21NO5
1-(tert-Butyl) 2-ethyl 3-hydroxy-3,6-dihydropyridine-1,2(2H)-dicarboxylate chemical structure, C13H21NO5, CAS 1791437-56-3
1-(tert-Butyl) 2-ethyl 3-hydroxy-3,6-dihydropyridine-1,2(2H)-dicarboxylate
CAS 1791437-56-3C13H21NO5
Rel-1-(tert-butyl) 2-ethyl (2R,3R)-3-hydroxy-3,6-dihydropyridine-1,2(2H)-dicarboxylate chemical structure, C13H21NO5, CAS 1023361-16-1
Rel-1-(tert-butyl) 2-ethyl (2R,3R)-3-hydroxy-3,6-dihydropyridine-1,2(2H)-dicarboxylate
CAS 1023361-16-1C13H21NO5
tert-Butyl 3-chloro-1,2,3,6-tetrahydropyridine-1-carboxylate chemical structure, C10H16ClNO2, CAS 2055344-88-0
tert-Butyl 3-chloro-1,2,3,6-tetrahydropyridine-1-carboxylate
CAS 2055344-88-0C10H16ClNO2
1,1-Dimethylethyl N-[(1,2,5,6-tetrahydro-3-pyridinyl)methyl]carbamate chemical structure, C11H20N2O2, CAS 1936457-16-7
1,1-Dimethylethyl N-[(1,2,5,6-tetrahydro-3-pyridinyl)methyl]carbamate
CAS 1936457-16-7C11H20N2O2
tert-Butyl 4-(1-methanesulfonylethenyl)-1,2,3,6-tetrahydropyridine-1-carboxylate chemical structure, C13H21NO4S, CAS 2059943-56-3
tert-Butyl 4-(1-methanesulfonylethenyl)-1,2,3,6-tetrahydropyridine-1-carboxylate
CAS 2059943-56-3C13H21NO4S
1-(N-Acetyl)-3,6-Dihydro-2H-4-iodopyridine chemical structure, C7H10INO, CAS 1622844-26-1
1-(N-Acetyl)-3,6-Dihydro-2H-4-iodopyridine
CAS 1622844-26-1C7H10INO
N-Methyl-2-[4-(trifluoromethyl)-1,2,3,6-tetrahydropyridin-1-yl]acetamide chemical structure, C9H13F3N2O, CAS 2093882-25-6
N-Methyl-2-[4-(trifluoromethyl)-1,2,3,6-tetrahydropyridin-1-yl]acetamide
CAS 2093882-25-6C9H13F3N2O
N-[1-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)ethyl]prop-2-enamide chemical structure, C11H18N2O, CAS 2094317-15-2
N-[1-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)ethyl]prop-2-enamide
CAS 2094317-15-2C11H18N2O
tert-Butyl 3-Fluoro-5,6-dihydropyridine-1(2H)-carboxylate chemical structure, C10H16FNO2, CAS 1861803-23-7
tert-Butyl 3-Fluoro-5,6-dihydropyridine-1(2H)-carboxylate
CAS 1861803-23-7C10H16FNO2
tert-Butyl (S)-3-methyl-4-(((trifluoromethyl)sulfonyl)oxy)-3,6-dihydropyridine-1(2H)-carboxylate chemical structure, C12H18F3NO5S, CAS 2149584-05-2
tert-Butyl (S)-3-methyl-4-(((trifluoromethyl)sulfonyl)oxy)-3,6-dihydropyridine-1(2H)-carboxylate
CAS 2149584-05-2C12H18F3NO5S
1-Acetyl-3,6-dihydro-2H-pyridine-5-carboxamide chemical structure, C8H12N2O2, CAS 15828-01-0
1-Acetyl-3,6-dihydro-2H-pyridine-5-carboxamide
CAS 15828-01-0C8H12N2O2
Ethyl 5-fluoro-1,2,3,6-tetrahydropyridine-4-carboxylate chemical structure, C8H12FNO2, CAS 1237526-38-3
Ethyl 5-fluoro-1,2,3,6-tetrahydropyridine-4-carboxylate
CAS 1237526-38-3C8H12FNO2