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Murcko scaffold

Ring system with 2 rings and 11 atoms

23 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
23
With full pages
6
Scaffold SMILES

O=C1CCCN1c1cn[nH]c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCN1c1cn[nH]c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

1-(1-Methyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C9H11N3O3, CAS 1153971-08-4
1-(1-Methyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 1153971-08-4C9H11N3O3
4-Amino-1-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one chemical structure, C8H12N4O, CAS 1153292-03-5
4-Amino-1-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one
CAS 1153292-03-5C8H12N4O
5-Oxo-1-(1H-pyrazol-4-yl)pyrrolidine-3-carboxylic acid chemical structure, C8H9N3O3, CAS 1156167-68-8
5-Oxo-1-(1H-pyrazol-4-yl)pyrrolidine-3-carboxylic acid
CAS 1156167-68-8C8H9N3O3
3-Bromo-1-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one chemical structure, C8H10BrN3O, CAS 1311314-47-2
3-Bromo-1-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one
CAS 1311314-47-2C8H10BrN3O
3-Amino-1-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one chemical structure, C8H12N4O, CAS 1247359-59-6
3-Amino-1-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one
CAS 1247359-59-6C8H12N4O
1-(1-(2-Methoxyethyl)-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C11H15N3O4, CAS 1275458-73-5
1-(1-(2-Methoxyethyl)-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 1275458-73-5C11H15N3O4
3-Amino-5-methyl-1-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one chemical structure, C9H14N4O, CAS 1354949-34-0
3-Amino-5-methyl-1-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one
CAS 1354949-34-0C9H14N4O
1-(1-Methyl-1H-pyrazol-4-yl)-2-oxopyrrolidine-3-carboxylic acid chemical structure, C9H11N3O3, CAS 1528717-87-4
1-(1-Methyl-1H-pyrazol-4-yl)-2-oxopyrrolidine-3-carboxylic acid
CAS 1528717-87-4C9H11N3O3
5-Oxo-1-(1,3,5-trimethyl-1H-pyrazol-4-yl)-pyrrolidine-3-carboxylic acid chemical structure, C11H15N3O3, CAS 1707369-84-3
5-Oxo-1-(1,3,5-trimethyl-1H-pyrazol-4-yl)-pyrrolidine-3-carboxylic acid
CAS 1707369-84-3C11H15N3O3
1-(1-Butyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C12H17N3O3, CAS 1708401-84-6
1-(1-Butyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 1708401-84-6C12H17N3O3
5-Oxo-1-(1-pentyl-1H-pyrazol-4-yl)pyrrolidine-3-carboxylic acid chemical structure, C13H19N3O3, CAS 1710203-20-5
5-Oxo-1-(1-pentyl-1H-pyrazol-4-yl)pyrrolidine-3-carboxylic acid
CAS 1710203-20-5C13H19N3O3
1-(1-(sec-Butyl)-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C12H17N3O3, CAS 1710293-41-6
1-(1-(sec-Butyl)-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 1710293-41-6C12H17N3O3
1-(1-Isobutyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C12H17N3O3, CAS 1707603-46-0
1-(1-Isobutyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 1707603-46-0C12H17N3O3
5-Oxo-1-(1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl)pyrrolidine-3-carboxylic acid chemical structure, C10H10F3N3O3, CAS 1707386-76-2
5-Oxo-1-(1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl)pyrrolidine-3-carboxylic acid
CAS 1707386-76-2C10H10F3N3O3
1-(1-(2-(Dimethylamino)ethyl)-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C12H18N4O3, CAS 1708437-35-7
1-(1-(2-(Dimethylamino)ethyl)-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 1708437-35-7C12H18N4O3
1-(1-Hexyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C14H21N3O3, CAS 1707579-41-6
1-(1-Hexyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 1707579-41-6C14H21N3O3
3-[Methyl(prop-2-yn-1-yl)amino]-1-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one chemical structure, C12H16N4O, CAS 1808358-09-9
3-[Methyl(prop-2-yn-1-yl)amino]-1-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one
CAS 1808358-09-9C12H16N4O
4-Amino-1-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one dihydrochloride chemical structure, C8H14Cl2N4O, CAS 2059684-74-9
4-Amino-1-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-2-one dihydrochloride
CAS 2059684-74-9C8H14Cl2N4O
Methyl 1-(1-methyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylate chemical structure, C10H13N3O3, CAS 1989672-48-1
Methyl 1-(1-methyl-1H-pyrazol-4-yl)-5-oxopyrrolidine-3-carboxylate
CAS 1989672-48-1C10H13N3O3
N-[1-(1-Methylpyrazol-4-yl)-5-oxopyrrolidin-3-yl]but-2-ynamide chemical structure, C12H14N4O2, CAS 2249128-87-6
N-[1-(1-Methylpyrazol-4-yl)-5-oxopyrrolidin-3-yl]but-2-ynamide
CAS 2249128-87-6C12H14N4O2
2-Chloro-N-(5-methyl-1-(1-methyl-1H-pyrazol-4-yl)-2-oxopyrrolidin-3-yl)acetamide chemical structure, C11H15ClN4O2, CAS 2411199-65-8
2-Chloro-N-(5-methyl-1-(1-methyl-1H-pyrazol-4-yl)-2-oxopyrrolidin-3-yl)acetamide
CAS 2411199-65-8C11H15ClN4O2
N-[5-Methyl-1-(1-methyl-1H-pyrazol-4-yl)-2-oxopyrrolidin-3-yl]prop-2-enamide chemical structure, C12H16N4O2, CAS 2411199-42-1
N-[5-Methyl-1-(1-methyl-1H-pyrazol-4-yl)-2-oxopyrrolidin-3-yl]prop-2-enamide
CAS 2411199-42-1C12H16N4O2
1-{1-[(tert-Butoxy)carbonyl]-1H-pyrazol-4-yl}-5-oxopyrrolidine-3-carboxylic acid chemical structure, C13H17N3O5, CAS 2680856-12-4
1-{1-[(tert-Butoxy)carbonyl]-1H-pyrazol-4-yl}-5-oxopyrrolidine-3-carboxylic acid
CAS 2680856-12-4C13H17N3O5