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Murcko scaffold

Ring system with 2 rings and 13 atoms

21 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 13
Chemicals: 21
With full pages: 6

Scaffold SMILES

C=C1SCC(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold C=C1SCC(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

(E)-2-Cyano-2-(5-ethyl-3-(4-fluorophenyl)-4-oxothiazolidin-2-ylidene)acetamide chemical structure, C14H12FN3O2S, CAS 1164503-76-7

(E)-2-Cyano-2-(5-ethyl-3-(4-fluorophenyl)-4-oxothiazolidin-2-ylidene)acetamide

CAS 1164503-76-7C₁₄H₁₂FN₃O₂S

(E)-2-Cyano-2-(3-(4-fluorophenyl)-5-methyl-4-oxothiazolidin-2-ylidene)acetamide chemical structure, C13H10FN3O2S, CAS 1164547-40-3

(E)-2-Cyano-2-(3-(4-fluorophenyl)-5-methyl-4-oxothiazolidin-2-ylidene)acetamide

CAS 1164547-40-3C₁₃H₁₀FN₃O₂S

2-(4-Oxo-3-phenyl-1,3-thiazolidin-2-ylidene)propanedinitrile chemical structure, C12H7N3OS, CAS 59615-89-3

2-(4-Oxo-3-phenyl-1,3-thiazolidin-2-ylidene)propanedinitrile

CAS 59615-89-3C₁₂H₇N₃OS

2-[3-(2-Methylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]propanedinitrile chemical structure, C13H9N3OS, CAS 702668-92-6

2-[3-(2-Methylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]propanedinitrile

CAS 702668-92-6C₁₃H₉N₃OS

(2Z)-3-(4-Chlorophenyl)-2-(nitromethylidene)-1,3-thiazolidin-4-one chemical structure, C10H7ClN2O3S, CAS 338417-48-4

(2Z)-3-(4-Chlorophenyl)-2-(nitromethylidene)-1,3-thiazolidin-4-one

CAS 338417-48-4C₁₀H₇ClN₂O₃S

(2Z)-3-(4-Fluorophenyl)-2-(nitromethylidene)-1,3-thiazolidin-4-one chemical structure, C10H7FN2O3S, CAS 338417-49-5

(2Z)-3-(4-Fluorophenyl)-2-(nitromethylidene)-1,3-thiazolidin-4-one

CAS 338417-49-5C₁₀H₇FN₂O₃S

(2Z)-2-(Nitromethylidene)-3-phenyl-1,3-thiazolidin-4-one chemical structure, C10H8N2O3S, CAS 1164508-39-7

(2Z)-2-(Nitromethylidene)-3-phenyl-1,3-thiazolidin-4-one

CAS 1164508-39-7C₁₀H₈N₂O₃S

(2Z)-3-(4-Methoxyphenyl)-2-(nitromethylidene)-1,3-thiazolidin-4-one chemical structure, C11H10N2O4S, CAS 1164474-29-6

(2Z)-3-(4-Methoxyphenyl)-2-(nitromethylidene)-1,3-thiazolidin-4-one

CAS 1164474-29-6C₁₁H₁₀N₂O₄S

2-[(2Z)-4-Oxo-2-(2-oxopropylidene)-3-phenyl-1,3-thiazolidin-5-yl]acetic acid chemical structure, C14H13NO4S, CAS 1164536-80-4

2-[(2Z)-4-Oxo-2-(2-oxopropylidene)-3-phenyl-1,3-thiazolidin-5-yl]acetic acid

CAS 1164536-80-4C₁₄H₁₃NO₄S

(2Z)-2-Cyano-2-[5-ethyl-3-(4-fluorophenyl)-4-oxo-1,3-thiazolidin-2-ylidene]acetamide chemical structure, C14H12FN3O2S, CAS 850238-48-1

(2Z)-2-Cyano-2-[5-ethyl-3-(4-fluorophenyl)-4-oxo-1,3-thiazolidin-2-ylidene]acetamide

CAS 850238-48-1C₁₄H₁₂FN₃O₂S

(Z)-2-Cyano-2-(5-(2-hydroxyethyl)-4-oxo-3-phenylthiazolidin-2-ylidene)-N-methylacetamide chemical structure, C15H15N3O3S, CAS 799820-16-9

(Z)-2-Cyano-2-(5-(2-hydroxyethyl)-4-oxo-3-phenylthiazolidin-2-ylidene)-N-methylacetamide

CAS 799820-16-9C₁₅H₁₅N₃O₃S

2-Cyano-2-[5-ethyl-3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]acetamide chemical structure, C15H15N3O2S, CAS 850230-76-1

2-Cyano-2-[5-ethyl-3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]acetamide

CAS 850230-76-1C₁₅H₁₅N₃O₂S

(2Z)-2-Cyano-2-[3-(4-fluorophenyl)-5-methyl-4-oxo-1,3-thiazolidin-2-ylidene]acetamide chemical structure, C13H10FN3O2S, CAS 877810-26-9

(2Z)-2-Cyano-2-[3-(4-fluorophenyl)-5-methyl-4-oxo-1,3-thiazolidin-2-ylidene]acetamide

CAS 877810-26-9C₁₃H₁₀FN₃O₂S

2-[3-(4-Chlorophenyl)-5-methyl-4-oxo-1,3-thiazolidin-2-ylidene]-2-cyano-N-methylacetamide chemical structure, C14H12ClN3O2S, CAS 877796-39-9

2-[3-(4-Chlorophenyl)-5-methyl-4-oxo-1,3-thiazolidin-2-ylidene]-2-cyano-N-methylacetamide

CAS 877796-39-9C₁₄H₁₂ClN₃O₂S

(2Z)-2-(Nitromethylidene)-3-[4-(trifluoromethoxy)phenyl]-1,3-thiazolidin-4-one chemical structure, C11H7F3N2O4S, CAS 1164500-27-9

(2Z)-2-(Nitromethylidene)-3-[4-(trifluoromethoxy)phenyl]-1,3-thiazolidin-4-one

CAS 1164500-27-9C₁₁H₇F₃N₂O₄S

(2Z)-2-[3-(4-Chlorophenyl)-5-ethyl-4-oxo-1,3-thiazolidin-2-ylidene]-2-cyano-N-methylacetamide chemical structure, C15H14ClN3O2S, CAS 850231-36-6

(2Z)-2-[3-(4-Chlorophenyl)-5-ethyl-4-oxo-1,3-thiazolidin-2-ylidene]-2-cyano-N-methylacetamide

CAS 850231-36-6C₁₅H₁₄ClN₃O₂S

(Z)-2-Cyano-2-(4-oxo-3-phenylthiazolidin-2-ylidene)acetamide chemical structure, C12H9N3O2S, CAS 91417-63-9

(Z)-2-Cyano-2-(4-oxo-3-phenylthiazolidin-2-ylidene)acetamide

CAS 91417-63-9C₁₂H₉N₃O₂S

2-Cyano-2-[5-ethyl-3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]-N-methylacetamide chemical structure, C16H17N3O2S, CAS 898645-82-4

2-Cyano-2-[5-ethyl-3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]-N-methylacetamide

CAS 898645-82-4C₁₆H₁₇N₃O₂S

2-Cyano-N-methyl-2-[5-methyl-3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]acetamide chemical structure, C15H15N3O2S, CAS 898645-76-6

2-Cyano-N-methyl-2-[5-methyl-3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]acetamide

CAS 898645-76-6C₁₅H₁₅N₃O₂S

(E)-2-Cyano-2-(5-methyl-4-oxo-3-(p-tolyl)thiazolidin-2-ylidene)acetamide chemical structure, C14H13N3O2S, CAS 877794-09-7

(E)-2-Cyano-2-(5-methyl-4-oxo-3-(p-tolyl)thiazolidin-2-ylidene)acetamide

CAS 877794-09-7C₁₄H₁₃N₃O₂S

Methyl 2-cyano-2-[(2E)-4-oxo-3-phenyl-1,3-thiazolidin-2-ylidene]acetate chemical structure, C13H10N2O3S, CAS 133713-10-7

Methyl 2-cyano-2-[(2E)-4-oxo-3-phenyl-1,3-thiazolidin-2-ylidene]acetate

CAS 133713-10-7C₁₃H₁₀N₂O₃S