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Murcko scaffold

4-(Pyridine-2-carbonyl)morpholine scaffold

36 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
36
With full pages
3
Scaffold SMILES

O=C(c1ccccn1)N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Pyridine-2-carbonyl)morpholine page
Murcko scaffold O=C(c1ccccn1)N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

4-((3-Hydroxy-2-pyridyl)carbonyl)morpholine chemical structure, C10H12N2O3, CAS 1206-87-7
4-((3-Hydroxy-2-pyridyl)carbonyl)morpholine
CAS 1206-87-7C10H12N2O3
4-(Pyridine-2-carbonyl)morpholine chemical structure, C10H12N2O2, CAS 112657-38-2
4-(Pyridine-2-carbonyl)morpholine
CAS 112657-38-2C10H12N2O2
6-(Morpholine-4-carbonyl)nicotinic acid, t-butyl ester chemical structure, C15H20N2O4, CAS 163587-56-2
6-(Morpholine-4-carbonyl)nicotinic acid, t-butyl ester
CAS 163587-56-2C15H20N2O4
[5-(3,4-Dichlorobutyl)pyridin-2-yl](morpholin-4-yl)methanone chemical structure, C14H18Cl2N2O2, CAS 58247-60-2
[5-(3,4-Dichlorobutyl)pyridin-2-yl](morpholin-4-yl)methanone
CAS 58247-60-2C14H18Cl2N2O2
4-((5-Bromopyridin-2-yl)carbonyl)morpholine chemical structure, C10H11BrN2O2, CAS 957063-06-8
4-((5-Bromopyridin-2-yl)carbonyl)morpholine
CAS 957063-06-8C10H11BrN2O2
(3,6-Dichloropyridin-2-yl)(morpholino)methanone chemical structure, C10H10Cl2N2O2, CAS 1021043-40-2
(3,6-Dichloropyridin-2-yl)(morpholino)methanone
CAS 1021043-40-2C10H10Cl2N2O2
4-(4-Chloropyridine-2-carbonyl)morpholine chemical structure, C10H11ClN2O2, CAS 1094306-26-9
4-(4-Chloropyridine-2-carbonyl)morpholine
CAS 1094306-26-9C10H11ClN2O2
4-(3,6-Dichloropyridine-2-carbonyl)-2,6-dimethylmorpholine chemical structure, C12H14Cl2N2O2, CAS 1021043-63-9
4-(3,6-Dichloropyridine-2-carbonyl)-2,6-dimethylmorpholine
CAS 1021043-63-9C12H14Cl2N2O2
Methyl 6-(4-morpholinylcarbonyl)-2-pyridinecarboxylate chemical structure, C12H14N2O4, CAS 1790616-80-6
Methyl 6-(4-morpholinylcarbonyl)-2-pyridinecarboxylate
CAS 1790616-80-6C12H14N2O4
(5-Bromopyridin-2-yl)(3,3-dimethylmorpholino)methanone chemical structure, C12H15BrN2O2, CAS 1275237-07-4
(5-Bromopyridin-2-yl)(3,3-dimethylmorpholino)methanone
CAS 1275237-07-4C12H15BrN2O2
(4-Bromopyridin-2-yl)(morpholino)methanone chemical structure, C10H11BrN2O2, CAS 947534-68-1
(4-Bromopyridin-2-yl)(morpholino)methanone
CAS 947534-68-1C10H11BrN2O2
(6-Hydroxymethylpyridin-2-yl)morpholin-4-ylmethanone chemical structure, C11H14N2O3, CAS 868769-71-5
(6-Hydroxymethylpyridin-2-yl)morpholin-4-ylmethanone
CAS 868769-71-5C11H14N2O3
4-(6-Bromopyridine-2-carbonyl)morpholine chemical structure, C10H11BrN2O2, CAS 892548-20-8
4-(6-Bromopyridine-2-carbonyl)morpholine
CAS 892548-20-8C10H11BrN2O2
(2-(Aminomethyl)morpholino)(6-methylpyridin-2-yl)methanone chemical structure, C12H17N3O2, CAS 1837263-88-3
(2-(Aminomethyl)morpholino)(6-methylpyridin-2-yl)methanone
CAS 1837263-88-3C12H17N3O2
4-[(6-Chloropyridin-2-yl)carbonyl]morpholine chemical structure, C10H11ClN2O2, CAS 720693-08-3
4-[(6-Chloropyridin-2-yl)carbonyl]morpholine
CAS 720693-08-3C10H11ClN2O2
(5-Aminopyridin-2-yl)(morpholino)methanone chemical structure, C10H13N3O2, CAS 1180131-89-8
(5-Aminopyridin-2-yl)(morpholino)methanone
CAS 1180131-89-8C10H13N3O2
4-[(6-Methoxypyridin-2-yl)carbonyl]morpholine chemical structure, C11H14N2O3, CAS 1791419-73-2
4-[(6-Methoxypyridin-2-yl)carbonyl]morpholine
CAS 1791419-73-2C11H14N2O3
5-Bromo-3-methyl-2-morpholinocarbonylpyridine chemical structure, C11H13BrN2O2, CAS 244139-60-4
5-Bromo-3-methyl-2-morpholinocarbonylpyridine
CAS 244139-60-4C11H13BrN2O2
4-(5-Chloropyridine-2-carbonyl)morpholine-3-carbonitrile chemical structure, C11H10ClN3O2, CAS 1436205-66-1
4-(5-Chloropyridine-2-carbonyl)morpholine-3-carbonitrile
CAS 1436205-66-1C11H10ClN3O2
(3,6-Dichloropyridin-2-yl)-(3,5-dimethylmorpholin-4-yl)methanone chemical structure, C12H14Cl2N2O2, CAS 1436144-47-6
(3,6-Dichloropyridin-2-yl)-(3,5-dimethylmorpholin-4-yl)methanone
CAS 1436144-47-6C12H14Cl2N2O2
2-Morpholinocarbonyl-5-nitropyridine chemical structure, C10H11N3O4, CAS 1445322-59-7
2-Morpholinocarbonyl-5-nitropyridine
CAS 1445322-59-7C10H11N3O4
[4-(Hydroxymethyl)-2-pyridinyl]-4-morpholinylmethanone chemical structure, C11H14N2O3, CAS 332013-44-2
[4-(Hydroxymethyl)-2-pyridinyl]-4-morpholinylmethanone
CAS 332013-44-2C11H14N2O3
(5-Fluoro-pyridin-2-yl)-morpholin-4-yl-methanone chemical structure, C10H11FN2O2, CAS 1443243-17-1
(5-Fluoro-pyridin-2-yl)-morpholin-4-yl-methanone
CAS 1443243-17-1C10H11FN2O2
4-(3,6-Dibromopyridine-2-carbonyl)morpholine-3-carbonitrile chemical structure, C11H9Br2N3O2, CAS 1795357-68-4
4-(3,6-Dibromopyridine-2-carbonyl)morpholine-3-carbonitrile
CAS 1795357-68-4C11H9Br2N3O2