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Murcko scaffold

2-Cyclobutylthiophene scaffold

317 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
317
With full pages
6
Scaffold SMILES

c1csc(C2CCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Cyclobutylthiophene page
Murcko scaffold c1csc(C2CCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 317 chemicals

2,2,3,3-Tetramethoxy-4-thiophen-2-ylcyclobutane-1,1-dicarbonitrile chemical structure, C14H16N2O4S, CAS 56069-55-7
2,2,3,3-Tetramethoxy-4-thiophen-2-ylcyclobutane-1,1-dicarbonitrile
CAS 56069-55-7C14H16N2O4S
[1-(Thiophen-2-yl)cyclobutyl]methanamine chemical structure, C9H13NS, CAS 115816-35-8
[1-(Thiophen-2-yl)cyclobutyl]methanamine
CAS 115816-35-8C9H13NS
1-Thien-2-ylcyclobutanecarboxylic acid chemical structure, C9H10O2S, CAS 202737-33-5
1-Thien-2-ylcyclobutanecarboxylic acid
CAS 202737-33-5C9H10O2S
1-Thien-2-ylcyclobutanecarbonitrile chemical structure, C9H9NS, CAS 28049-65-2
1-Thien-2-ylcyclobutanecarbonitrile
CAS 28049-65-2C9H9NS
(5-Cyclobutylthiophen-2-yl)boronic acid chemical structure, C8H11BO2S, CAS 2225178-93-6
(5-Cyclobutylthiophen-2-yl)boronic acid
CAS 2225178-93-6C8H11BO2S
2-Bromo-5-(cyclobutyl)thiophene chemical structure, C8H9BrS, CAS 1159815-85-6
2-Bromo-5-(cyclobutyl)thiophene
CAS 1159815-85-6C8H9BrS
1-(5-Chlorothiophen-2-yl)cyclobutane-1-carbonitrile chemical structure, C9H8ClNS, CAS 880166-07-4
1-(5-Chlorothiophen-2-yl)cyclobutane-1-carbonitrile
CAS 880166-07-4C9H8ClNS
1-(5-Chlorothiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C9H9ClO2S, CAS 880166-08-5
1-(5-Chlorothiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 880166-08-5C9H9ClO2S
Methyl 2-amino-5-cyclobutylthiophene-3-carboxylate chemical structure, C10H13NO2S, CAS 439693-01-3
Methyl 2-amino-5-cyclobutylthiophene-3-carboxylate
CAS 439693-01-3C10H13NO2S
1-(Thiophen-2-yl)cyclobutan-1-amine chemical structure, C8H11NS, CAS 1247844-28-5
1-(Thiophen-2-yl)cyclobutan-1-amine
CAS 1247844-28-5C8H11NS
3-Methyl-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C10H12O2S, CAS 1339467-98-9
3-Methyl-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 1339467-98-9C10H12O2S
3,3-Dimethoxy-1-(2-thienyl)cyclobutanecarbonitrile chemical structure, C11H13NO2S, CAS 1379019-84-7
3,3-Dimethoxy-1-(2-thienyl)cyclobutanecarbonitrile
CAS 1379019-84-7C11H13NO2S
3,3-Dimethyl-1-(thiophen-2-yl)cyclobutan-1-amine chemical structure, C10H15NS, CAS 1489484-84-5
3,3-Dimethyl-1-(thiophen-2-yl)cyclobutan-1-amine
CAS 1489484-84-5C10H15NS
3-Ethyl-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C11H14O2S, CAS 1469139-91-0
3-Ethyl-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 1469139-91-0C11H14O2S
3,3-Dimethyl-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C11H14O2S, CAS 880166-21-2
3,3-Dimethyl-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 880166-21-2C11H14O2S
(3,3-Dimethyl-1-(thiophen-2-yl)cyclobutyl)methanamine chemical structure, C11H17NS, CAS 1508686-04-1
(3,3-Dimethyl-1-(thiophen-2-yl)cyclobutyl)methanamine
CAS 1508686-04-1C11H17NS
3-Propyl-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C12H16O2S, CAS 1466258-46-7
3-Propyl-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 1466258-46-7C12H16O2S
3-(Propan-2-yl)-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C12H16O2S, CAS 1509663-85-7
3-(Propan-2-yl)-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 1509663-85-7C12H16O2S
3-(Aminomethyl)-3-(thiophen-2-yl)cyclobutan-1-ol chemical structure, C9H13NOS, CAS 1498779-15-9
3-(Aminomethyl)-3-(thiophen-2-yl)cyclobutan-1-ol
CAS 1498779-15-9C9H13NOS
3-Hydroxy-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C9H10O3S, CAS 1498757-57-5
3-Hydroxy-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 1498757-57-5C9H10O3S
2-Methyl-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C10H12O2S, CAS 1505720-17-1
2-Methyl-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 1505720-17-1C10H12O2S
5-Cyclobutylthiophen-2-amine chemical structure, C8H11NS, CAS 1314357-02-2
5-Cyclobutylthiophen-2-amine
CAS 1314357-02-2C8H11NS
2-Cyclobutylthiophene chemical structure, C8H10S, CAS 2567505-02-4
2-Cyclobutylthiophene
CAS 2567505-02-4C8H10S
3-(5-Methylthiophen-2-yl)cyclobutan-1-ol chemical structure, C9H12OS, CAS 1515416-07-5
3-(5-Methylthiophen-2-yl)cyclobutan-1-ol
CAS 1515416-07-5C9H12OS