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Murcko scaffold

2-Cyclobutylthiophene scaffold

317 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
317
With full pages
6
Scaffold SMILES

c1csc(C2CCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Cyclobutylthiophene page
Murcko scaffold c1csc(C2CCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 317 chemicals

1-(4-Methylthiophen-2-yl)cyclobutan-1-amine chemical structure, C9H13NS, CAS 1542564-90-8
1-(4-Methylthiophen-2-yl)cyclobutan-1-amine
CAS 1542564-90-8C9H13NS
1-(5-Methylthiophen-2-yl)cyclobutan-1-amine chemical structure, C9H13NS, CAS 1508588-17-7
1-(5-Methylthiophen-2-yl)cyclobutan-1-amine
CAS 1508588-17-7C9H13NS
1-(3-Methylthiophen-2-yl)cyclobutan-1-amine chemical structure, C9H13NS, CAS 1506634-32-7
1-(3-Methylthiophen-2-yl)cyclobutan-1-amine
CAS 1506634-32-7C9H13NS
1-[1-(3-Methylthiophen-2-yl)cyclobutyl]methanamine chemical structure, C10H15NS, CAS 1501334-39-9
1-[1-(3-Methylthiophen-2-yl)cyclobutyl]methanamine
CAS 1501334-39-9C10H15NS
1-[1-(4-Methylthiophen-2-yl)cyclobutyl]methanamine chemical structure, C10H15NS, CAS 1523447-02-0
1-[1-(4-Methylthiophen-2-yl)cyclobutyl]methanamine
CAS 1523447-02-0C10H15NS
1-(3-Methylthiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C10H12O2S, CAS 1513232-27-3
1-(3-Methylthiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 1513232-27-3C10H12O2S
1-(4-Methylthiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C10H12O2S, CAS 1498980-48-5
1-(4-Methylthiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 1498980-48-5C10H12O2S
1-(5-Methylthiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C10H12O2S, CAS 1501440-70-5
1-(5-Methylthiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 1501440-70-5C10H12O2S
1-(3-Ethylthiophen-2-yl)cyclobutan-1-amine chemical structure, C10H15NS, CAS 1526215-75-7
1-(3-Ethylthiophen-2-yl)cyclobutan-1-amine
CAS 1526215-75-7C10H15NS
1-[1-(3-Ethylthiophen-2-yl)cyclobutyl]methanamine chemical structure, C11H17NS, CAS 1528421-41-1
1-[1-(3-Ethylthiophen-2-yl)cyclobutyl]methanamine
CAS 1528421-41-1C11H17NS
1-(3-Ethylthiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C11H14O2S, CAS 1533016-36-2
1-(3-Ethylthiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 1533016-36-2C11H14O2S
1-[5-(Trifluoromethyl)thiophen-2-yl]cyclobutan-1-amine chemical structure, C9H10F3NS, CAS 1504001-79-9
1-[5-(Trifluoromethyl)thiophen-2-yl]cyclobutan-1-amine
CAS 1504001-79-9C9H10F3NS
1-(3-Bromothiophen-2-yl)cyclobutan-1-amine chemical structure, C8H10BrNS, CAS 1514849-55-8
1-(3-Bromothiophen-2-yl)cyclobutan-1-amine
CAS 1514849-55-8C8H10BrNS
1-{1-[5-(Trifluoromethyl)thiophen-2-yl]cyclobutyl}methanamine chemical structure, C10H12F3NS, CAS 1535399-84-8
1-{1-[5-(Trifluoromethyl)thiophen-2-yl]cyclobutyl}methanamine
CAS 1535399-84-8C10H12F3NS
[1-(5-Bromothiophen-2-yl)cyclobutyl]methanamine chemical structure, C9H12BrNS, CAS 1803604-58-1
[1-(5-Bromothiophen-2-yl)cyclobutyl]methanamine
CAS 1803604-58-1C9H12BrNS
1-[1-(3-Bromothiophen-2-yl)cyclobutyl]methanamine chemical structure, C9H12BrNS, CAS 2228197-05-3
1-[1-(3-Bromothiophen-2-yl)cyclobutyl]methanamine
CAS 2228197-05-3C9H12BrNS
1-(5-Bromothiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C9H9BrO2S, CAS 2228970-46-3
1-(5-Bromothiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 2228970-46-3C9H9BrO2S
1-(3-Bromothiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C9H9BrO2S, CAS 2229483-08-1
1-(3-Bromothiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 2229483-08-1C9H9BrO2S
1-(5-Bromothiophen-2-yl)cyclobutan-1-ol chemical structure, C8H9BrOS, CAS 1807502-89-1
1-(5-Bromothiophen-2-yl)cyclobutan-1-ol
CAS 1807502-89-1C8H9BrOS
1-(3-Methylthiophen-2-yl)cyclobutane-1-carbonitrile chemical structure, C10H11NS, CAS 1896483-98-9
1-(3-Methylthiophen-2-yl)cyclobutane-1-carbonitrile
CAS 1896483-98-9C10H11NS
1-[1-(4-Bromothiophen-2-yl)cyclobutyl]methanamine chemical structure, C9H12BrNS, CAS 1890344-92-9
1-[1-(4-Bromothiophen-2-yl)cyclobutyl]methanamine
CAS 1890344-92-9C9H12BrNS
1-(4-Bromothiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C9H9BrO2S, CAS 1893827-96-7
1-(4-Bromothiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 1893827-96-7C9H9BrO2S
[1-(4-Bromothiophen-2-yl)cyclobutyl]methanol chemical structure, C9H11BrOS, CAS 1895171-37-5
[1-(4-Bromothiophen-2-yl)cyclobutyl]methanol
CAS 1895171-37-5C9H11BrOS
Methyl 1-(5-bromothiophen-2-yl)cyclobutane-1-carboxylate chemical structure, C10H11BrO2S, CAS 1890317-64-2
Methyl 1-(5-bromothiophen-2-yl)cyclobutane-1-carboxylate
CAS 1890317-64-2C10H11BrO2S