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Murcko scaffold

2-Cyclobutylthiophene scaffold

317 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
317
With full pages
6
Scaffold SMILES

c1csc(C2CCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Cyclobutylthiophene page
Murcko scaffold c1csc(C2CCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 289 to 317 of 317 chemicals

3,3-Difluoro-1-(4-methylthiophen-2-yl)cyclobutan-1-amine chemical structure, C9H11F2NS, CAS 2228135-00-8
3,3-Difluoro-1-(4-methylthiophen-2-yl)cyclobutan-1-amine
CAS 2228135-00-8C9H11F2NS
[3,3-Difluoro-1-(5-nitrothiophen-2-yl)cyclobutyl]methanamine chemical structure, C9H10F2N2O2S, CAS 2229560-01-2
[3,3-Difluoro-1-(5-nitrothiophen-2-yl)cyclobutyl]methanamine
CAS 2229560-01-2C9H10F2N2O2S
1-[1-(5-Propylthiophen-2-yl)cyclobutyl]methanamine chemical structure, C12H19NS, CAS 2229365-32-4
1-[1-(5-Propylthiophen-2-yl)cyclobutyl]methanamine
CAS 2229365-32-4C12H19NS
5-(1-Amino-3,3-difluorocyclobutyl)thiophene-3-carbonitrile chemical structure, C9H8F2N2S, CAS 2228250-19-7
5-(1-Amino-3,3-difluorocyclobutyl)thiophene-3-carbonitrile
CAS 2228250-19-7C9H8F2N2S
2-Amino-5-cyclobutylthiophene-3-carboxylic acid chemical structure, C9H11NO2S, CAS 2169192-09-8
2-Amino-5-cyclobutylthiophene-3-carboxylic acid
CAS 2169192-09-8C9H11NO2S
5-Cyclobutyl-2-acetamidothiophene-3-carboxylic acid chemical structure, C11H13NO3S, CAS 2680756-06-1
5-Cyclobutyl-2-acetamidothiophene-3-carboxylic acid
CAS 2680756-06-1C11H13NO3S
5-Cyclobutyl-2-(2,2,2-trifluoroacetamido)thiophene-3-carboxylic acid chemical structure, C11H10F3NO3S, CAS 2680788-16-1
5-Cyclobutyl-2-(2,2,2-trifluoroacetamido)thiophene-3-carboxylic acid
CAS 2680788-16-1C11H10F3NO3S
tert-Butyl N-{[1-(5-bromothiophen-2-yl)cyclobutyl]methyl}carbamate chemical structure, C14H20BrNO2S, CAS 2680751-17-9
tert-Butyl N-{[1-(5-bromothiophen-2-yl)cyclobutyl]methyl}carbamate
CAS 2680751-17-9C14H20BrNO2S
5-Cyclobutyl-2-{[(prop-2-en-1-yloxy)carbonyl]amino}thiophene-3-carboxylic acid chemical structure, C13H15NO4S, CAS 2680667-51-8
5-Cyclobutyl-2-{[(prop-2-en-1-yloxy)carbonyl]amino}thiophene-3-carboxylic acid
CAS 2680667-51-8C13H15NO4S
3-Amino-3-(3-bromo-5-methylthiophen-2-yl)cyclobutan-1-ol chemical structure, C9H12BrNOS, CAS 2228186-48-7
3-Amino-3-(3-bromo-5-methylthiophen-2-yl)cyclobutan-1-ol
CAS 2228186-48-7C9H12BrNOS
2-[1-(3-Bromo-4-methylthiophen-2-yl)cyclobutyl]ethan-1-amine chemical structure, C11H16BrNS, CAS 2228641-14-1
2-[1-(3-Bromo-4-methylthiophen-2-yl)cyclobutyl]ethan-1-amine
CAS 2228641-14-1C11H16BrNS
2-[1-(5-Propylthiophen-2-yl)cyclobutyl]acetic acid chemical structure, C13H18O2S, CAS 2229203-70-5
2-[1-(5-Propylthiophen-2-yl)cyclobutyl]acetic acid
CAS 2229203-70-5C13H18O2S
3-Amino-1-(5-methylthiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C10H13NO2S, CAS 2228217-35-2
3-Amino-1-(5-methylthiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 2228217-35-2C10H13NO2S
[1-(3-Bromo-5-methylthiophen-2-yl)cyclobutyl]methanol chemical structure, C10H13BrOS, CAS 2228882-09-3
[1-(3-Bromo-5-methylthiophen-2-yl)cyclobutyl]methanol
CAS 2228882-09-3C10H13BrOS
3-Amino-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C9H11NO2S, CAS 2229525-82-8
3-Amino-1-(thiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 2229525-82-8C9H11NO2S
3,3-Difluoro-1-(5-nitrothiophen-2-yl)cyclobutan-1-amine chemical structure, C8H8F2N2O2S, CAS 2229425-04-9
3,3-Difluoro-1-(5-nitrothiophen-2-yl)cyclobutan-1-amine
CAS 2229425-04-9C8H8F2N2O2S
1-(3-Bromo-4-methylthiophen-2-yl)cyclobutane-1-carbonitrile chemical structure, C10H10BrNS, CAS 2228903-60-2
1-(3-Bromo-4-methylthiophen-2-yl)cyclobutane-1-carbonitrile
CAS 2228903-60-2C10H10BrNS
[1-(3-Ethylthiophen-2-yl)cyclobutyl]methanol chemical structure, C11H16OS, CAS 2229269-31-0
[1-(3-Ethylthiophen-2-yl)cyclobutyl]methanol
CAS 2229269-31-0C11H16OS
3-Hydroxy-1-(4-methylthiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C10H12O3S, CAS 2228500-21-6
3-Hydroxy-1-(4-methylthiophen-2-yl)cyclobutane-1-carboxylic acid
CAS 2228500-21-6C10H12O3S
3,3-Difluoro-1-(5-propylthiophen-2-yl)cyclobutan-1-amine chemical structure, C11H15F2NS, CAS 2228664-56-8
3,3-Difluoro-1-(5-propylthiophen-2-yl)cyclobutan-1-amine
CAS 2228664-56-8C11H15F2NS
1-(4-Chlorothiophen-2-yl)cyclobutane-1-carbonitrile chemical structure, C9H8ClNS, CAS 2228210-65-7
1-(4-Chlorothiophen-2-yl)cyclobutane-1-carbonitrile
CAS 2228210-65-7C9H8ClNS
Methyl 5-(1-cyanocyclobutyl)thiophene-2-carboxylate chemical structure, C11H11NO2S, CAS 2229523-97-9
Methyl 5-(1-cyanocyclobutyl)thiophene-2-carboxylate
CAS 2229523-97-9C11H11NO2S
3-(Aminomethyl)-3-(5-bromothiophen-2-yl)cyclobutan-1-ol chemical structure, C9H12BrNOS, CAS 2228716-59-2
3-(Aminomethyl)-3-(5-bromothiophen-2-yl)cyclobutan-1-ol
CAS 2228716-59-2C9H12BrNOS
3-Amino-3-(4-methylthiophen-2-yl)cyclobutan-1-ol chemical structure, C9H13NOS, CAS 2229257-31-0
3-Amino-3-(4-methylthiophen-2-yl)cyclobutan-1-ol
CAS 2229257-31-0C9H13NOS