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Murcko scaffold

5-(3-Pyridyl)-4H-1,2,4-triazole-3-thiol scaffold

26 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
26
With full pages
6
Scaffold SMILES

S=c1nc(-c2cccnc2)[nH][nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(3-Pyridyl)-4H-1,2,4-triazole-3-thiol page
Murcko scaffold S=c1nc(-c2cccnc2)[nH][nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

5-(3-Pyridyl)-4H-1,2,4-triazole-3-thiol chemical structure, C7H6N4S, CAS 32362-88-2
5-(3-Pyridyl)-4H-1,2,4-triazole-3-thiol
CAS 32362-88-2C7H6N4S
4-Methyl-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C8H8N4S, CAS 3652-31-1
4-Methyl-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 3652-31-1C8H8N4S
4-Ethyl-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol chemical structure, C9H10N4S, CAS 26131-68-0
4-Ethyl-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol
CAS 26131-68-0C9H10N4S
4-Allyl-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol chemical structure, C10H10N4S, CAS 80570-89-4
4-Allyl-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol
CAS 80570-89-4C10H10N4S
4-Amino-5-pyridin-3-yl-4H-(1,2,4)triazole-3-thiol chemical structure, C7H7N5S, CAS 78027-00-6
4-Amino-5-pyridin-3-yl-4H-(1,2,4)triazole-3-thiol
CAS 78027-00-6C7H7N5S
4-Butyl-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C11H14N4S, CAS 91969-16-3
4-Butyl-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 91969-16-3C11H14N4S
4-(2-Methoxyethyl)-5-pyridin-3-yl-4H-1,2,4-triazole-3-thiol chemical structure, C10H12N4OS, CAS 380574-00-5
4-(2-Methoxyethyl)-5-pyridin-3-yl-4H-1,2,4-triazole-3-thiol
CAS 380574-00-5C10H12N4OS
5-(6-Chloro-3-pyridyl)-4-methyl-4H-1,2,4-triazole-3-thiol chemical structure, C8H7ClN4S, CAS 306936-79-8
5-(6-Chloro-3-pyridyl)-4-methyl-4H-1,2,4-triazole-3-thiol
CAS 306936-79-8C8H7ClN4S
1H-1,2,4-Triazole-3-thiol, 5-(3-pyridyl)-, hydrochloride chemical structure, C7H7ClN4S, CAS 4923-16-4
1H-1,2,4-Triazole-3-thiol, 5-(3-pyridyl)-, hydrochloride
CAS 4923-16-4C7H7ClN4S
4-Isobutyl-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol chemical structure, C11H14N4S, CAS 23746-43-2
4-Isobutyl-5-pyridin-3-yl-4H-[1,2,4]triazole-3-thiol
CAS 23746-43-2C11H14N4S
5-(5-Bromopyridin-3-yl)-4-methyl-4H-1,2,4-triazole-3-thiol chemical structure, C8H7BrN4S, CAS 951970-16-4
5-(5-Bromopyridin-3-yl)-4-methyl-4H-1,2,4-triazole-3-thiol
CAS 951970-16-4C8H7BrN4S
4-Propyl-5-pyridin-3-YL-4H-1,2,4-triazole-3-thiol chemical structure, C10H12N4S, CAS 90871-44-6
4-Propyl-5-pyridin-3-YL-4H-1,2,4-triazole-3-thiol
CAS 90871-44-6C10H12N4S
4-Isopropyl-5-pyridin-3-YL-4H-1,2,4-triazole-3-thiol chemical structure, C10H12N4S, CAS 90871-42-4
4-Isopropyl-5-pyridin-3-YL-4H-1,2,4-triazole-3-thiol
CAS 90871-42-4C10H12N4S
4-Amino-5-(5-bromopyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C7H6BrN5S, CAS 1019061-93-8
4-Amino-5-(5-bromopyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 1019061-93-8C7H6BrN5S
5-(Pyridin-3-yl)-4-(2,2,2-trifluoroethyl)-4H-1,2,4-triazole-3-thiol chemical structure, C9H7F3N4S, CAS 1152597-46-0
5-(Pyridin-3-yl)-4-(2,2,2-trifluoroethyl)-4H-1,2,4-triazole-3-thiol
CAS 1152597-46-0C9H7F3N4S
Methyl 2-[3-(pyridin-3-yl)-5-sulfanyl-4H-1,2,4-triazol-4-yl]acetate chemical structure, C10H10N4O2S, CAS 1152591-28-0
Methyl 2-[3-(pyridin-3-yl)-5-sulfanyl-4H-1,2,4-triazol-4-yl]acetate
CAS 1152591-28-0C10H10N4O2S
4-(2-Ethoxyethyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C11H14N4OS, CAS 1156130-68-5
4-(2-Ethoxyethyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 1156130-68-5C11H14N4OS
4-Neopentyl-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C12H16N4S, CAS 1307101-62-7
4-Neopentyl-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 1307101-62-7C12H16N4S
5-(5-Aminopyridin-3-yl)-4-methyl-4H-1,2,4-triazole-3-thiol chemical structure, C8H9N5S, CAS 1423031-18-8
5-(5-Aminopyridin-3-yl)-4-methyl-4H-1,2,4-triazole-3-thiol
CAS 1423031-18-8C8H9N5S
5-Pyridin-3-yl-4H-1,2,4-triazole-3-thiol-1H-imidazole (1:1) chemical structure, C10H10N6S, CAS 1983937-80-9
5-Pyridin-3-yl-4H-1,2,4-triazole-3-thiol-1H-imidazole (1:1)
CAS 1983937-80-9C10H10N6S
5-(5-Fluoropyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C7H5FN4S, CAS 1565439-40-8
5-(5-Fluoropyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 1565439-40-8C7H5FN4S
2,4-Dihydro-4-methyl-5-(5-methyl-3-pyridinyl)-3H-1,2,4-triazole-3-thione chemical structure, C9H10N4S, CAS 914096-57-4
2,4-Dihydro-4-methyl-5-(5-methyl-3-pyridinyl)-3H-1,2,4-triazole-3-thione
CAS 914096-57-4C9H10N4S
4-(2,2-Difluoroethyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C9H8F2N4S, CAS 1545655-91-1
4-(2,2-Difluoroethyl)-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 1545655-91-1C9H8F2N4S
(R)-3-(4-Allyl-3-(pyridin-3-yl)-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-2-aminopropanoic acid chemical structure, C13H15N5O2S, CAS 1381976-06-2
(R)-3-(4-Allyl-3-(pyridin-3-yl)-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-2-aminopropanoic acid
CAS 1381976-06-2C13H15N5O2S