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Murcko scaffold

Ring system with 4 rings and 25 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
6
With full pages
3
Scaffold SMILES

O=S(=O)(c1ccccc1)N1N=C(c2cccs2)CC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1N=C(c2cccs2)CC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

5-(4-Bromophenyl)-1-(phenylsulfonyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole chemical structure, C19H15BrN2O2S2, CAS 361480-35-5
5-(4-Bromophenyl)-1-(phenylsulfonyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole
CAS 361480-35-5C19H15BrN2O2S2
5-(4-Fluorophenyl)-1-(phenylsulfonyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole chemical structure, C19H15FN2O2S2, CAS 361480-24-2
5-(4-Fluorophenyl)-1-(phenylsulfonyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole
CAS 361480-24-2C19H15FN2O2S2
2-(Benzenesulfonyl)-3-(3-nitrophenyl)-5-thiophen-2-yl-3,4-dihydropyrazole chemical structure, C19H15N3O4S2, CAS 392308-49-5
2-(Benzenesulfonyl)-3-(3-nitrophenyl)-5-thiophen-2-yl-3,4-dihydropyrazole
CAS 392308-49-5C19H15N3O4S2
3-(4-Methoxyphenyl)-2-(4-methylphenyl)sulfonyl-5-thiophen-2-yl-3,4-dihydropyrazole chemical structure, C21H20N2O3S2, CAS 361480-20-8
3-(4-Methoxyphenyl)-2-(4-methylphenyl)sulfonyl-5-thiophen-2-yl-3,4-dihydropyrazole
CAS 361480-20-8C21H20N2O3S2
5-(4-Methoxyphenyl)-1-(phenylsulfonyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole chemical structure, C20H18N2O3S2, CAS 887199-99-7
5-(4-Methoxyphenyl)-1-(phenylsulfonyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole
CAS 887199-99-7C20H18N2O3S2
2-(1-(Phenylsulfonyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-5-yl)phenol chemical structure, C19H16N2O3S2, CAS 868214-21-5
2-(1-(Phenylsulfonyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-5-yl)phenol
CAS 868214-21-5C19H16N2O3S2