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Murcko scaffold

4-(Phenylsulfonyl)-5-(piperidin-1-yl)-2-(thiophen-2-yl)oxazole scaffold

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
11
With full pages
5
Scaffold SMILES

O=S(=O)(c1ccccc1)c1nc(-c2cccs2)oc1N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Phenylsulfonyl)-5-(piperidin-1-yl)-2-(thiophen-2-yl)oxazole page
Murcko scaffold O=S(=O)(c1ccccc1)c1nc(-c2cccs2)oc1N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

1-(4-(Phenylsulfonyl)-2-(thiophen-2-yl)oxazol-5-yl)piperidine-4-carboxamide chemical structure, C19H19N3O4S2, CAS 627833-46-9
1-(4-(Phenylsulfonyl)-2-(thiophen-2-yl)oxazol-5-yl)piperidine-4-carboxamide
CAS 627833-46-9C19H19N3O4S2
5-(Piperidin-1-yl)-2-(thiophen-2-yl)-4-tosyloxazole chemical structure, C19H20N2O3S2, CAS 627833-52-7
5-(Piperidin-1-yl)-2-(thiophen-2-yl)-4-tosyloxazole
CAS 627833-52-7C19H20N2O3S2
5-(4-Methylpiperidin-1-yl)-4-(phenylsulfonyl)-2-(thiophen-2-yl)oxazole chemical structure, C19H20N2O3S2, CAS 627832-90-0
5-(4-Methylpiperidin-1-yl)-4-(phenylsulfonyl)-2-(thiophen-2-yl)oxazole
CAS 627832-90-0C19H20N2O3S2
4-(Phenylsulfonyl)-5-(piperidin-1-yl)-2-(thiophen-2-yl)oxazole chemical structure, C18H18N2O3S2, CAS 627832-82-0
4-(Phenylsulfonyl)-5-(piperidin-1-yl)-2-(thiophen-2-yl)oxazole
CAS 627832-82-0C18H18N2O3S2
5-(3,5-Dimethylpiperidin-1-yl)-4-(phenylsulfonyl)-2-(thiophen-2-yl)oxazole chemical structure, C20H22N2O3S2, CAS 627833-33-4
5-(3,5-Dimethylpiperidin-1-yl)-4-(phenylsulfonyl)-2-(thiophen-2-yl)oxazole
CAS 627833-33-4C20H22N2O3S2
5-(4-Methylpiperidin-1-yl)-2-(thiophen-2-yl)-4-tosyloxazole chemical structure, C20H22N2O3S2, CAS 627833-56-1
5-(4-Methylpiperidin-1-yl)-2-(thiophen-2-yl)-4-tosyloxazole
CAS 627833-56-1C20H22N2O3S2
5-(3,5-Dimethylpiperidin-1-yl)-4-(4-methylphenyl)sulfonyl-2-thiophen-2-yl-1,3-oxazole chemical structure, C21H24N2O3S2, CAS 7065-36-3
5-(3,5-Dimethylpiperidin-1-yl)-4-(4-methylphenyl)sulfonyl-2-thiophen-2-yl-1,3-oxazole
CAS 7065-36-3C21H24N2O3S2
1-(2-(Thiophen-2-yl)-4-tosyloxazol-5-yl)piperidine-4-carboxamide chemical structure, C20H21N3O4S2, CAS 627834-00-8
1-(2-(Thiophen-2-yl)-4-tosyloxazol-5-yl)piperidine-4-carboxamide
CAS 627834-00-8C20H21N3O4S2
4-((4-Chlorophenyl)sulfonyl)-5-(piperidin-1-yl)-2-(thiophen-2-yl)oxazole chemical structure, C18H17ClN2O3S2, CAS 627834-62-2
4-((4-Chlorophenyl)sulfonyl)-5-(piperidin-1-yl)-2-(thiophen-2-yl)oxazole
CAS 627834-62-2C18H17ClN2O3S2
4-((4-Chlorophenyl)sulfonyl)-5-(4-methylpiperidin-1-yl)-2-(thiophen-2-yl)oxazole chemical structure, C19H19ClN2O3S2, CAS 627834-66-6
4-((4-Chlorophenyl)sulfonyl)-5-(4-methylpiperidin-1-yl)-2-(thiophen-2-yl)oxazole
CAS 627834-66-6C19H19ClN2O3S2
1-[4-(4-Bromophenyl)sulfonyl-2-thiophen-2-yl-1,3-oxazol-5-yl]piperidine-4-carboxamide chemical structure, C19H18BrN3O4S2, CAS 627836-16-2
1-[4-(4-Bromophenyl)sulfonyl-2-thiophen-2-yl-1,3-oxazol-5-yl]piperidine-4-carboxamide
CAS 627836-16-2C19H18BrN3O4S2