Murcko scaffold
Ring system with 4 rings and 25 atoms
6 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 25
- Chemicals
- 6
- With full pages
- 1
Scaffold SMILES
O=S(=O)(c1ccccc1)c1nc(-c2cccs2)oc1N1CCNCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
![1-Methyl-4-[4-(phenylsulfonyl)-2-(2-thienyl)-1,3-oxazol-5-yl]piperazine chemical structure, C18H19N3O3S2, CAS 627833-14-1](/s/WGXCCGRRPCONNE-UHFFFAOYSA-N.svg)
1-Methyl-4-[4-(phenylsulfonyl)-2-(2-thienyl)-1,3-oxazol-5-yl]piperazine
CAS 627833-14-1C18H19N3O3S2
5-(4-Ethylpiperazin-1-yl)-4-(phenylsulfonyl)-2-(thiophen-2-yl)oxazole
CAS 627833-25-4C19H21N3O3S2
5-(4-Ethylpiperazin-1-yl)-2-(thiophen-2-yl)-4-tosyloxazole
CAS 627833-79-8C20H23N3O3S2
5-(4-Ethylpiperazin-1-yl)-4-(4-fluorophenyl)sulfonyl-2-thiophen-2-yl-1,3-oxazole
CAS 7065-41-0C19H20FN3O3S2
4-((4-Chlorophenyl)sulfonyl)-5-(4-methylpiperazin-1-yl)-2-(thiophen-2-yl)oxazole
CAS 627834-79-1C18H18ClN3O3S2
4-(4-Chlorophenyl)sulfonyl-5-(4-ethylpiperazin-1-yl)-2-thiophen-2-yl-1,3-oxazole
CAS 627834-89-3C19H20ClN3O3S2
Related scaffolds
Same ring framework with different atoms or bond orders
O=S(=O)(c1ccccc1)c1nc(-c2cccs2)oc1N1CCCCC15 chemicals
O=S(=O)(c1ccccc1)c1nc(-c2ccco2)oc1N1CCCCC14 chemicals
O=S(=O)(c1ccccc1)N1N=C(c2cccs2)CC1c1ccccc13 chemicals
O=C(c1ccccc1)N1N=C(c2cccs2)CC1c1ccccc12 chemicals
O=S(=O)(c1ccccc1)c1nc(-c2ccco2)oc1N1CCNCC11 chemical
O=S(=O)(c1ccccc1)c1nc(-c2ccco2)oc1N1CCOCC11 chemical