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Murcko scaffold

1-(4-Benzenesulfonyl-2-furan-2-yl-oxazol-5-yl)-piperidine scaffold

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
14
With full pages
4
Scaffold SMILES

O=S(=O)(c1ccccc1)c1nc(-c2ccco2)oc1N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(4-Benzenesulfonyl-2-furan-2-yl-oxazol-5-yl)-piperidine page
Murcko scaffold O=S(=O)(c1ccccc1)c1nc(-c2ccco2)oc1N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

4-((4-Chlorophenyl)sulfonyl)-2-(furan-2-yl)-5-(piperidin-1-yl)oxazole chemical structure, C18H17ClN2O4S, CAS 303753-67-5
4-((4-Chlorophenyl)sulfonyl)-2-(furan-2-yl)-5-(piperidin-1-yl)oxazole
CAS 303753-67-5C18H17ClN2O4S
1-[4-(Benzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]piperidine-4-carboxamide chemical structure, C19H19N3O5S, CAS 823829-56-7
1-[4-(Benzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]piperidine-4-carboxamide
CAS 823829-56-7C19H19N3O5S
1-{2-(Furan-2-yl)-4-[(4-methylphenyl)sulfonyl]-1,3-oxazol-5-yl}-4-methylpiperidine chemical structure, C20H22N2O4S, CAS 823829-60-3
1-{2-(Furan-2-yl)-4-[(4-methylphenyl)sulfonyl]-1,3-oxazol-5-yl}-4-methylpiperidine
CAS 823829-60-3C20H22N2O4S
1-(4-Benzenesulfonyl-2-furan-2-yl-oxazol-5-yl)-piperidine chemical structure, C18H18N2O4S, CAS 303753-71-1
1-(4-Benzenesulfonyl-2-furan-2-yl-oxazol-5-yl)-piperidine
CAS 303753-71-1C18H18N2O4S
2-(Furan-2-yl)-5-(piperidin-1-yl)-4-tosyloxazole chemical structure, C19H20N2O4S, CAS 313958-86-0
2-(Furan-2-yl)-5-(piperidin-1-yl)-4-tosyloxazole
CAS 313958-86-0C19H20N2O4S
5-(3,5-Dimethylpiperidin-1-yl)-2-(furan-2-yl)-4-(phenylsulfonyl)oxazole chemical structure, C20H22N2O4S, CAS 853902-21-3
5-(3,5-Dimethylpiperidin-1-yl)-2-(furan-2-yl)-4-(phenylsulfonyl)oxazole
CAS 853902-21-3C20H22N2O4S
2-(Furan-2-yl)-5-(4-methylpiperidin-1-yl)-4-(phenylsulfonyl)oxazole chemical structure, C19H20N2O4S, CAS 853902-22-4
2-(Furan-2-yl)-5-(4-methylpiperidin-1-yl)-4-(phenylsulfonyl)oxazole
CAS 853902-22-4C19H20N2O4S
4-((4-Chlorophenyl)sulfonyl)-2-(furan-2-yl)-5-(4-methylpiperidin-1-yl)oxazole chemical structure, C19H19ClN2O4S, CAS 862794-27-2
4-((4-Chlorophenyl)sulfonyl)-2-(furan-2-yl)-5-(4-methylpiperidin-1-yl)oxazole
CAS 862794-27-2C19H19ClN2O4S
1-(4-((4-Chlorophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)piperidine-4-carboxamide chemical structure, C19H18ClN3O5S, CAS 862794-93-2
1-(4-((4-Chlorophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)piperidine-4-carboxamide
CAS 862794-93-2C19H18ClN3O5S
5-(3,5-Dimethylpiperidin-1-yl)-2-(furan-2-yl)-4-tosyloxazole chemical structure, C21H24N2O4S, CAS 862793-58-6
5-(3,5-Dimethylpiperidin-1-yl)-2-(furan-2-yl)-4-tosyloxazole
CAS 862793-58-6C21H24N2O4S
1-(2-(Furan-2-yl)-4-tosyloxazol-5-yl)piperidine-4-carboxamide chemical structure, C20H21N3O5S, CAS 883248-50-8
1-(2-(Furan-2-yl)-4-tosyloxazol-5-yl)piperidine-4-carboxamide
CAS 883248-50-8C20H21N3O5S
1-(4-((4-Fluorophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)piperidine-4-carboxamide chemical structure, C19H18FN3O5S, CAS 862794-12-5
1-(4-((4-Fluorophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)piperidine-4-carboxamide
CAS 862794-12-5C19H18FN3O5S
4-((4-Chlorophenyl)sulfonyl)-5-(3,5-dimethylpiperidin-1-yl)-2-(furan-2-yl)oxazole chemical structure, C20H21ClN2O4S, CAS 862794-80-7
4-((4-Chlorophenyl)sulfonyl)-5-(3,5-dimethylpiperidin-1-yl)-2-(furan-2-yl)oxazole
CAS 862794-80-7C20H21ClN2O4S
4-((4-Bromophenyl)sulfonyl)-2-(furan-2-yl)-5-(4-methylpiperidin-1-yl)oxazole chemical structure, C19H19BrN2O4S, CAS 862795-02-6
4-((4-Bromophenyl)sulfonyl)-2-(furan-2-yl)-5-(4-methylpiperidin-1-yl)oxazole
CAS 862795-02-6C19H19BrN2O4S