Murcko scaffold
3H,4H,5H,6H,7H-(1,2,3)Triazolo(4,5-c)pyridine scaffold
57 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 57
- With full pages
- 3
Scaffold SMILES
C1Cc2[nH]nnc2CN1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold C1Cc2[nH]nnc2CN1](/scaffold/GIIMNWTYRGWBNQ-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 57 chemicals
![1-Methyl-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine chemical structure, C6H10N4, CAS 160752-39-6](/s/IHVDOLNSCCKRKP-UHFFFAOYSA-N.svg)
1-Methyl-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine
CAS 160752-39-6C6H10N4
3H,4H,5H,6H,7H-(1,2,3)Triazolo(4,5-c)pyridine
CAS 706757-05-3C5H8N4
![1,4-Diethyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5(4H)-carbaldehyde chemical structure, C10H16N4O, CAS 485402-42-4](/s/NNGFJEQODRCUPL-UHFFFAOYSA-N.svg)
1,4-Diethyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5(4H)-carbaldehyde
CAS 485402-42-4C10H16N4O
![6,7-Dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5(4H)-carbaldehyde chemical structure, C6H8N4O, CAS 485402-45-7](/s/OTLNTAZCEJJZBD-UHFFFAOYSA-N.svg)
6,7-Dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5(4H)-carbaldehyde
CAS 485402-45-7C6H8N4O
![1,5-Dimethyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine chemical structure, C7H12N4, CAS 787526-95-8](/s/IBRYXLSQHKFOEI-UHFFFAOYSA-N.svg)
1,5-Dimethyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine
CAS 787526-95-8C7H12N4
![5-Methyl-4,5,6,7-tetrahydro-3H-[1,2,3]triazolo[4,5-c]pyridine chemical structure, C6H10N4, CAS 1849200-42-5](/s/WCKUGCHFEKZKEB-UHFFFAOYSA-N.svg)
5-Methyl-4,5,6,7-tetrahydro-3H-[1,2,3]triazolo[4,5-c]pyridine
CAS 1849200-42-5C6H10N4
![1-Methyl-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine dihydrochloride chemical structure, C6H12Cl2N4, CAS 485402-33-3](/s/LOTWQJDKGXKTIL-UHFFFAOYSA-N.svg)
1-Methyl-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine dihydrochloride
CAS 485402-33-3C6H12Cl2N4
![1-(2,2,2-Trifluoroethyl)-4,5,6,7-tetrahydrotriazolo[4,5-c]pyridine chemical structure, C7H9F3N4, CAS 1162661-95-1](/s/OYVMJNTZZACXRM-UHFFFAOYSA-N.svg)
1-(2,2,2-Trifluoroethyl)-4,5,6,7-tetrahydrotriazolo[4,5-c]pyridine
CAS 1162661-95-1C7H9F3N4
![3-Methyl-4,5,6,7-tetrahydro-3H-[1,2,3]triazolo[4,5-C]pyridine chemical structure, C6H10N4, CAS 733758-57-1](/s/ROEVJSDXPACVSR-UHFFFAOYSA-N.svg)
3-Methyl-4,5,6,7-tetrahydro-3H-[1,2,3]triazolo[4,5-C]pyridine
CAS 733758-57-1C6H10N4
![1-(2-Methylpropyl)-4,5,6,7-tetrahydrotriazolo[4,5-c]pyridine chemical structure, C9H16N4, CAS 733758-52-6](/s/WCAYLHUGDPCYIM-UHFFFAOYSA-N.svg)
1-(2-Methylpropyl)-4,5,6,7-tetrahydrotriazolo[4,5-c]pyridine
CAS 733758-52-6C9H16N4
1-(2-Methoxyethyl)-1H,4H,5H,6H,7H-(1,2,3)triazolo(4,5-c)pyridine
CAS 1481032-08-9C8H14N4O
![1-Isopropyl-4,5,6,7-tetrahydrotriazolo[4,5-C]pyridine chemical structure, C8H14N4, CAS 1466053-31-5](/s/PGFDLDUPQFWXHT-UHFFFAOYSA-N.svg)
1-Isopropyl-4,5,6,7-tetrahydrotriazolo[4,5-C]pyridine
CAS 1466053-31-5C8H14N4
![1-(2,4,4-Trimethylpentan-2-yl)-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine chemical structure, C13H24N4, CAS 1486702-81-1](/s/IKEWOBBQLNAFNV-UHFFFAOYSA-N.svg)
1-(2,4,4-Trimethylpentan-2-yl)-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine
CAS 1486702-81-1C13H24N4
![3-Ethyl-3H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine chemical structure, C7H12N4, CAS 1779747-64-6](/s/BMROKHDHBCQWOQ-UHFFFAOYSA-N.svg)
3-Ethyl-3H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine
CAS 1779747-64-6C7H12N4
![5-tert-Butyl 7-methyl 1-ethyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5,7(4H)-dicarboxylate chemical structure, C14H22N4O4, CAS 1391732-98-1](/s/ZXYISKBNCFRHMO-UHFFFAOYSA-N.svg)
5-tert-Butyl 7-methyl 1-ethyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5,7(4H)-dicarboxylate
CAS 1391732-98-1C14H22N4O4
![5-(tert-Butoxycarbonyl)-1-ethyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine-7-carboxylic acid chemical structure, C13H20N4O4, CAS 1391733-65-5](/s/ICRDMQXZYFMJNL-UHFFFAOYSA-N.svg)
5-(tert-Butoxycarbonyl)-1-ethyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine-7-carboxylic acid
CAS 1391733-65-5C13H20N4O4
![5-tert-Butyl 7-methyl 1-methyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5,7(4H)-dicarboxylate chemical structure, C13H20N4O4, CAS 1391732-40-3](/s/VHWGXLJQQLURGI-UHFFFAOYSA-N.svg)
5-tert-Butyl 7-methyl 1-methyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5,7(4H)-dicarboxylate
CAS 1391732-40-3C13H20N4O4
![tert-Butyl 1-ethyl-7-(hydroxymethyl)-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5(4H)-carboxylate chemical structure, C13H22N4O3, CAS 1391732-88-9](/s/KUEFIWLOQFKUEL-UHFFFAOYSA-N.svg)
tert-Butyl 1-ethyl-7-(hydroxymethyl)-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5(4H)-carboxylate
CAS 1391732-88-9C13H22N4O3
![5-(tert-Butoxycarbonyl)-1-methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine-7-carboxylic acid chemical structure, C12H18N4O4, CAS 1391733-57-5](/s/XVFGRNPTDDWFIY-UHFFFAOYSA-N.svg)
5-(tert-Butoxycarbonyl)-1-methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine-7-carboxylic acid
CAS 1391733-57-5C12H18N4O4
![tert-Butyl 7-(hydroxymethyl)-1-methyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5(4H)-carboxylate chemical structure, C12H20N4O3, CAS 1391733-06-4](/s/GVDGDQSVCZMPJC-UHFFFAOYSA-N.svg)
tert-Butyl 7-(hydroxymethyl)-1-methyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5(4H)-carboxylate
CAS 1391733-06-4C12H20N4O3
![tert-Butyl 7-(aminomethyl)-1-methyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5(4H)-carboxylate chemical structure, C12H21N5O2, CAS 1391733-61-1](/s/JJYGGACJPRWUDR-UHFFFAOYSA-N.svg)
tert-Butyl 7-(aminomethyl)-1-methyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5(4H)-carboxylate
CAS 1391733-61-1C12H21N5O2
![3,4,6,7-Tetrahydro-[1,2,3]triazolo[4,5-c]pyridine-5-carboxylic acid tert-butyl ester chemical structure, C10H16N4O2, CAS 1251016-63-3](/s/ZRLOOYBJFUODRF-UHFFFAOYSA-N.svg)
3,4,6,7-Tetrahydro-[1,2,3]triazolo[4,5-c]pyridine-5-carboxylic acid tert-butyl ester
CAS 1251016-63-3C10H16N4O2
![2-(5-Methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridin-1-yl)acetic acid chemical structure, C8H12N4O2, CAS 1782441-69-3](/s/DWAZOOPTRKJUFX-UHFFFAOYSA-N.svg)
2-(5-Methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridin-1-yl)acetic acid
CAS 1782441-69-3C8H12N4O2
![3-(Propan-2-yl)-3H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-C]pyridine chemical structure, C8H14N4, CAS 1556119-24-4](/s/LOJFIOULIGGNBJ-UHFFFAOYSA-N.svg)
3-(Propan-2-yl)-3H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-C]pyridine
CAS 1556119-24-4C8H14N4
- 2-Methyl-4,5,6,7-tetrahydro-2H-[1,2,3]triazolo[4,5-c]pyridine1784081-16-8C6H10N4
- 1-(3,4,6,7-Tetrahydro-5H-[1,2,3]triazolo[4,5-c]pyridin-5-yl)ethan-1-one1862848-99-4C7H10N4O
- 2-Amino-1-(1-methyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridin-5(4H)-yl)ethanone1443287-31-7C8H13N5O
- 2-Bromo-1-(1-methyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridin-5(4H)-yl)propan-1-one1443290-41-2C9H13BrN4O
- 4,5,6,7-Tetrahydro-3H-[1,2,3]triazolo[4,5-c]pyridine hydrochloride1779934-40-5C5H9ClN4
- 7-(Ethoxymethyl)-1-ethyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine1422061-97-9C10H18N4O
- 7-(Ethoxymethyl)-1-methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine1422062-52-9C9H16N4O
- 7-(Methoxymethyl)-1-methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine1422133-22-9C8H14N4O
- 1-Ethyl-7-(methoxymethyl)-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine1422133-59-2C9H16N4O
- 1-Ethyl-4-(methoxymethyl)-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine1422138-44-0C9H16N4O
- 4-(Methoxymethyl)-1-methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine1422142-00-4C8H14N4O
- tert-Butyl 1-ethyl-6,7-dihydro-1H-[1,2,3]triazolo[4,5-c]pyridine-5(4H)-carboxylate1445951-79-0C12H20N4O2
- 1-(2,4,4-Trimethylpentan-2-yl)-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine hydrochloride1909316-75-1C13H25ClN4
- 3-tert-Butyl-3H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine1865121-29-4C9H16N4
- tert-Butyl 1-(prop-2-yn-1-yl)-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine-5-carboxylate2098142-62-0C13H18N4O2
- 5-Methyl-1-(prop-2-yn-1-yl)-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine2098135-30-7C9H12N4
- 1-(Prop-2-yn-1-yl)-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine dihydrochloride2097974-64-4C8H12Cl2N4
- 1-[1-(Prop-2-yn-1-yl)-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridin-5-yl]ethan-1-one2098135-34-1C10H12N4O
- 1-(Prop-2-yn-1-yl)-5-(propan-2-yl)-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine2098008-64-9C11H16N4
- 2,2,2-Trifluoro-1-(3,4,6,7-tetrahydro-5H-[1,2,3]triazolo[4,5-c]pyridin-5-yl)ethan-1-one1936001-76-1C7H7F3N4O
- tert-Butyl 4-(hydroxymethyl)-1-methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-5-carboxylate1422344-08-8C12H20N4O3
- AUrumpharma u468541422343-98-3C13H22N4O3
- 1-Methyl-4-(prop-2-enoxymethyl)-4,5,6,7-tetrahydrotriazolo[4,5-c]pyridine1422133-45-6C10H16N4O
- 4-((Allyloxy)methyl)-1-ethyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine1422142-76-4C11H18N4O
Related scaffolds
Same ring framework with different atoms or bond orders
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