CompoundList
Sign in
Murcko scaffold

1,4-Diphenylbutane scaffold

175 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
175
With full pages
27
Scaffold SMILES

c1ccc(CCCCc2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4-Diphenylbutane page
Murcko scaffold c1ccc(CCCCc2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 175 chemicals

Nordihydroguaretic acid chemical structure, C18H22O4, CAS 500-38-9
Nordihydroguaretic acid
CAS 500-38-9C18H22O4
(-)-Secoisolariciresinol chemical structure, C20H26O6, CAS 29388-59-8
(-)-Secoisolariciresinol
CAS 29388-59-8C20H26O6
1,4-Diphenylbutane chemical structure, C16H18, CAS 1083-56-3
1,4-Diphenylbutane
CAS 1083-56-3C16H18
Masoprocol chemical structure, C18H22O4, CAS 27686-84-6
Masoprocol
CAS 27686-84-6C18H22O4
2,4-Xylenol, 6,6'-butylidenebis- chemical structure, C20H26O2, CAS 3772-23-4
2,4-Xylenol, 6,6'-butylidenebis-
CAS 3772-23-4C20H26O2
Tetra-O-methyl nordihydroguaiaretic acid chemical structure, C22H30O4, CAS 5701-82-6
Tetra-O-methyl nordihydroguaiaretic acid
CAS 5701-82-6C22H30O4
Vetrabutine hydrochloride chemical structure, C20H28ClNO2, CAS 5974-09-4
Vetrabutine hydrochloride
CAS 5974-09-4C20H28ClNO2
alpha-(3,4-Dimethoxyphenyl)-N,N-dimethylbenzenebutanamine chemical structure, C20H27NO2, CAS 3735-45-3
alpha-(3,4-Dimethoxyphenyl)-N,N-dimethylbenzenebutanamine
CAS 3735-45-3C20H27NO2
Enterodiol chemical structure, C18H22O4, CAS 80226-00-2
Enterodiol
CAS 80226-00-2C18H22O4
Heminordihydroguaiaretic acid chemical structure, C19H24O4, CAS 54473-24-4
Heminordihydroguaiaretic acid
CAS 54473-24-4C19H24O4
2,3-Bis(3'-hydroxybenzyl)butane-1,4-diol chemical structure, C18H22O4, CAS 76543-16-3
2,3-Bis(3'-hydroxybenzyl)butane-1,4-diol
CAS 76543-16-3C18H22O4
2,3-Dibenzylbutane-1,4-diol chemical structure, C18H22O2, CAS 101787-58-0
2,3-Dibenzylbutane-1,4-diol
CAS 101787-58-0C18H22O2
Octane, 3,6-diphenyl- chemical structure, C20H26, CAS 21411-33-6
Octane, 3,6-diphenyl-
CAS 21411-33-6C20H26
Octane, 3,6-dimethyl-3,6-diphenyl- chemical structure, C22H30, CAS 21411-35-8
Octane, 3,6-dimethyl-3,6-diphenyl-
CAS 21411-35-8C22H30
Benzenebutanol, alpha-phenyl- chemical structure, C16H18O, CAS 30078-89-8
Benzenebutanol, alpha-phenyl-
CAS 30078-89-8C16H18O
Dihydroguaiaretic acid chemical structure, C20H26O4, CAS 36469-60-0
Dihydroguaiaretic acid
CAS 36469-60-0C20H26O4
Pregomisin chemical structure, C22H30O6, CAS 66280-26-0
Pregomisin
CAS 66280-26-0C22H30O6
1,4-Bis(3,4-diacetoxyphenyl)-2,3-dimethylbutane chemical structure, C26H30O8, CAS 65987-46-4
1,4-Bis(3,4-diacetoxyphenyl)-2,3-dimethylbutane
CAS 65987-46-4C26H30O8
4-(4-(4-Hydroxy-3-methoxyphenyl)butyl)-2-methoxyphenol chemical structure, C18H22O4, CAS 119189-41-2
4-(4-(4-Hydroxy-3-methoxyphenyl)butyl)-2-methoxyphenol
CAS 119189-41-2C18H22O4
Benzenepentanoic acid, alpha-phenyl-, 2-(diethylamino)ethyl ester, hydrochloride chemical structure, C23H32ClNO2, CAS 35047-67-7
Benzenepentanoic acid, alpha-phenyl-, 2-(diethylamino)ethyl ester, hydrochloride
CAS 35047-67-7C23H32ClNO2
Benzenepentanamide, N,N-diethyl-alpha-phenyl- chemical structure, C21H27NO, CAS 35068-35-0
Benzenepentanamide, N,N-diethyl-alpha-phenyl-
CAS 35068-35-0C21H27NO
6-Ethoxy-6-oxo-2,5-diphenylhexanoic acid chemical structure, C20H22O4, CAS 5435-10-9
6-Ethoxy-6-oxo-2,5-diphenylhexanoic acid
CAS 5435-10-9C20H22O4
2-(2-Carboxy-4-phenylbutyl)benzoic acid chemical structure, C18H18O4, CAS 5445-50-1
2-(2-Carboxy-4-phenylbutyl)benzoic acid
CAS 5445-50-1C18H18O4
Diethyl 2,2'-(butane-1,4-diyldibenzene-4,1-diyl)diacetate chemical structure, C24H30O4, CAS 6337-78-6
Diethyl 2,2'-(butane-1,4-diyldibenzene-4,1-diyl)diacetate
CAS 6337-78-6C24H30O4