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Murcko scaffold

Ring system with 2 rings and 15 atoms

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
17
With full pages
7
Scaffold SMILES

O=C(C=Cc1ccccc1)c1ccc[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)c1ccc[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

Methyl 2,4-dimethyl-5-(3-phenylprop-2-enoyl)-1H-pyrrole-3-carboxylate chemical structure, C17H17NO3, CAS 304876-74-2
Methyl 2,4-dimethyl-5-(3-phenylprop-2-enoyl)-1H-pyrrole-3-carboxylate
CAS 304876-74-2C17H17NO3
(E)-3-(2-Methoxyphenyl)-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]-2-propenenitrile chemical structure, C16H14N2O2, CAS 900019-51-4
(E)-3-(2-Methoxyphenyl)-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]-2-propenenitrile
CAS 900019-51-4C16H14N2O2
3-(3-Bromophenyl)-1-(1H-pyrrol-2-yl)-2-propen-1-one chemical structure, C13H10BrNO, CAS 1429049-47-7
3-(3-Bromophenyl)-1-(1H-pyrrol-2-yl)-2-propen-1-one
CAS 1429049-47-7C13H10BrNO
1-(1H-Pyrrol-2-yl)-3-(2,4,5-trimethoxyphenyl)-2-propen-1-one chemical structure, C16H17NO4, CAS 499182-98-8
1-(1H-Pyrrol-2-yl)-3-(2,4,5-trimethoxyphenyl)-2-propen-1-one
CAS 499182-98-8C16H17NO4
3-(3-Methoxyphenyl)-1-(1H-pyrrol-2-yl)prop-2-en-1-one chemical structure, C14H13NO2, CAS 1164496-46-1
3-(3-Methoxyphenyl)-1-(1H-pyrrol-2-yl)prop-2-en-1-one
CAS 1164496-46-1C14H13NO2
Methyl 5-[(E)-3-(2-fluorophenyl)prop-2-enoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate chemical structure, C17H16FNO3, CAS 370072-43-8
Methyl 5-[(E)-3-(2-fluorophenyl)prop-2-enoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate
CAS 370072-43-8C17H16FNO3
Methyl 2,4-dimethyl-5-[(E)-3-(4-methylphenyl)prop-2-enoyl]-1H-pyrrole-3-carboxylate chemical structure, C18H19NO3, CAS 300835-70-5
Methyl 2,4-dimethyl-5-[(E)-3-(4-methylphenyl)prop-2-enoyl]-1H-pyrrole-3-carboxylate
CAS 300835-70-5C18H19NO3
3-(2-Chlorophenyl)-1-(1H-pyrrol-2-yl)-2-propen-1-one chemical structure, C13H10ClNO, CAS 911052-94-3
3-(2-Chlorophenyl)-1-(1H-pyrrol-2-yl)-2-propen-1-one
CAS 911052-94-3C13H10ClNO
(E)-Methyl 5-(2-cyano-3-(4-(difluoromethoxy)phenyl)acryloyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate chemical structure, C19H16F2N2O4, CAS 315694-34-9
(E)-Methyl 5-(2-cyano-3-(4-(difluoromethoxy)phenyl)acryloyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate
CAS 315694-34-9C19H16F2N2O4
(2e)-3-Phenyl-1-(1H-pyrrol-2-yl)-2-propen-1-one chemical structure, C13H11NO, CAS 22563-48-0
(2e)-3-Phenyl-1-(1H-pyrrol-2-yl)-2-propen-1-one
CAS 22563-48-0C13H11NO
(E)-3-(4-Fluorophenyl)-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]-2-propenenitrile chemical structure, C15H11FN2O, CAS 900019-53-6
(E)-3-(4-Fluorophenyl)-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]-2-propenenitrile
CAS 900019-53-6C15H11FN2O
(E)-2-[(1-Methyl-1H-pyrrol-2-yl)carbonyl]-3-[2-(trifluoromethyl)phenyl]-2-propenenitrile chemical structure, C16H11F3N2O, CAS 900019-54-7
(E)-2-[(1-Methyl-1H-pyrrol-2-yl)carbonyl]-3-[2-(trifluoromethyl)phenyl]-2-propenenitrile
CAS 900019-54-7C16H11F3N2O
(E)-3-(4-Methoxyphenyl)-2-(1-methylpyrrole-2-carbonyl)prop-2-enenitrile chemical structure, C16H14N2O2, CAS 900019-57-0
(E)-3-(4-Methoxyphenyl)-2-(1-methylpyrrole-2-carbonyl)prop-2-enenitrile
CAS 900019-57-0C16H14N2O2
(E)-3-(3-Fluorophenyl)-1-(1H-pyrrol-2-yl)prop-2-en-1-one chemical structure, C13H10FNO, CAS 861427-63-6
(E)-3-(3-Fluorophenyl)-1-(1H-pyrrol-2-yl)prop-2-en-1-one
CAS 861427-63-6C13H10FNO
(E)-1-(5-Ethyl-1H-pyrrol-2-yl)-3-phenylprop-2-en-1-one chemical structure, C15H15NO, CAS 728008-72-8
(E)-1-(5-Ethyl-1H-pyrrol-2-yl)-3-phenylprop-2-en-1-one
CAS 728008-72-8C15H15NO
1-(1-Methyl-1H-pyrrol-2-yl)-3-phenylprop-2-en-1-one chemical structure, C14H13NO, CAS 16750-55-3
1-(1-Methyl-1H-pyrrol-2-yl)-3-phenylprop-2-en-1-one
CAS 16750-55-3C14H13NO
Orb3237083 chemical structure, C19H21NO3, CAS 3123321-73-0
Orb3237083
CAS 3123321-73-0C19H21NO3