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Murcko scaffold

4H,5H,6H,7H-Pyrazolo(1,5-a)pyrazin-4-one scaffold

115 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
115
With full pages
15
Scaffold SMILES

O=C1NCCn2nccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4H,5H,6H,7H-Pyrazolo(1,5-a)pyrazin-4-one page
Murcko scaffold O=C1NCCn2nccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 115 chemicals

Methyl 3-nitro-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate chemical structure, C8H8N4O5, CAS 459157-18-7
Methyl 3-nitro-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate
CAS 459157-18-7C8H8N4O5
3-Nitro-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide chemical structure, C7H7N5O4, CAS 459157-43-8
3-Nitro-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide
CAS 459157-43-8C7H7N5O4
3-Amino-5-ethyl-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide chemical structure, C9H13N5O2, CAS 459157-51-8
3-Amino-5-ethyl-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide
CAS 459157-51-8C9H13N5O2
Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo(1,5-a)pyrazine-2-carboxylate chemical structure, C9H11N3O3, CAS 951626-95-2
Ethyl 4-oxo-4,5,6,7-tetrahydropyrazolo(1,5-a)pyrazine-2-carboxylate
CAS 951626-95-2C9H11N3O3
Methyl 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate chemical structure, C8H9N3O3, CAS 604003-25-0
Methyl 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate
CAS 604003-25-0C8H9N3O3
7-Hydroxy-2-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one chemical structure, C7H9N3O2, CAS 1351772-44-5
7-Hydroxy-2-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one
CAS 1351772-44-5C7H9N3O2
4-Oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid chemical structure, C7H7N3O3, CAS 1029721-02-5
4-Oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid
CAS 1029721-02-5C7H7N3O3
4H,5H,6H,7H-Pyrazolo(1,5-a)pyrazin-4-one chemical structure, C6H7N3O, CAS 951626-38-3
4H,5H,6H,7H-Pyrazolo(1,5-a)pyrazin-4-one
CAS 951626-38-3C6H7N3O
3-Amino-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide chemical structure, C7H9N5O2, CAS 1189579-85-8
3-Amino-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide
CAS 1189579-85-8C7H9N5O2
3-Amino-5-methyl-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide chemical structure, C8H11N5O2, CAS 1189579-87-0
3-Amino-5-methyl-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide
CAS 1189579-87-0C8H11N5O2
3-Chloro-2-(hydroxymethyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one chemical structure, C7H8ClN3O2, CAS 1382786-15-3
3-Chloro-2-(hydroxymethyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one
CAS 1382786-15-3C7H8ClN3O2
3-Iodo-4-oxo-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine-2-carboxylic acid ethyl ester chemical structure, C9H10IN3O3, CAS 1382786-17-5
3-Iodo-4-oxo-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine-2-carboxylic acid ethyl ester
CAS 1382786-17-5C9H10IN3O3
5-Methyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-4-one chemical structure, C7H9N3O, CAS 2060026-96-0
5-Methyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-4-one
CAS 2060026-96-0C7H9N3O
5-Methyl-2-nitro-6,7-dihydropyrazolo[1,5-A]pyrazin-4(5H)-one chemical structure, C7H8N4O3, CAS 1408327-48-9
5-Methyl-2-nitro-6,7-dihydropyrazolo[1,5-A]pyrazin-4(5H)-one
CAS 1408327-48-9C7H8N4O3
2-Amino-5-methyl-4H,5H,6H,7H-pyrazolo(1,5-a)pyrazin-4-one chemical structure, C7H10N4O, CAS 1378683-88-5
2-Amino-5-methyl-4H,5H,6H,7H-pyrazolo(1,5-a)pyrazin-4-one
CAS 1378683-88-5C7H10N4O
2-(Trifluoromethyl)-4H,5H,6H,7H-pyrazolo(1,5-a)pyrazin-4-one chemical structure, C7H6F3N3O, CAS 1196153-16-8
2-(Trifluoromethyl)-4H,5H,6H,7H-pyrazolo(1,5-a)pyrazin-4-one
CAS 1196153-16-8C7H6F3N3O
4-Oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carbaldehyde chemical structure, C7H7N3O2, CAS 1378793-40-8
4-Oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carbaldehyde
CAS 1378793-40-8C7H7N3O2
2-Methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one chemical structure, C7H9N3O, CAS 1301714-05-5
2-Methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one
CAS 1301714-05-5C7H9N3O
5-tert-Butyl 2-methyl 6-methyl-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazine-2,5(4H)-dicarboxylate chemical structure, C14H19N3O5, CAS 1820603-32-4
5-tert-Butyl 2-methyl 6-methyl-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazine-2,5(4H)-dicarboxylate
CAS 1820603-32-4C14H19N3O5
Ethyl 6-methyl-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate chemical structure, C10H13N3O3, CAS 1820685-21-9
Ethyl 6-methyl-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate
CAS 1820685-21-9C10H13N3O3
6-Methyl-4-oxo-4H,5H,6H,7H-pyrazolo(1,5-a)pyrazine-2-carboxylic acid chemical structure, C8H9N3O3, CAS 1935580-16-7
6-Methyl-4-oxo-4H,5H,6H,7H-pyrazolo(1,5-a)pyrazine-2-carboxylic acid
CAS 1935580-16-7C8H9N3O3
2-(2-Methyl-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl)acetic acid chemical structure, C9H11N3O3, CAS 1708013-60-8
2-(2-Methyl-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl)acetic acid
CAS 1708013-60-8C9H11N3O3
2-(tert-Butyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one chemical structure, C10H15N3O, CAS 2169599-67-9
2-(tert-Butyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one
CAS 2169599-67-9C10H15N3O
3-Iodo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-4-one chemical structure, C6H6IN3O, CAS 1639901-82-8
3-Iodo-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-4-one
CAS 1639901-82-8C6H6IN3O