Murcko scaffold
Azepan-4-one scaffold
92 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 8
- Chemicals
- 92
- With full pages
- 15
Scaffold SMILES
O=C1CCCNCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 92 chemicals
1H-Azepine-1-carbothioic acid, hexahydro-4-oxo-, S-ethyl ester
CAS 70874-92-9C9H15NO2S
1-Methylazepan-4-one
CAS 1859-33-2C7H13NO
1-tert-Butyl-3,3,6,6-tetramethyl-5-oxoazepan-4-yl acetate
CAS 55886-34-5C16H29NO3
1-tert-Butyl-5-hydroxy-3,3,6,6-tetramethylazepan-4-one
CAS 55886-33-4C14H27NO2
Azepan-4-one
CAS 105416-56-6C6H11NO
N-Boc-hexahydro-1H-azepin-4-one
CAS 188975-88-4C11H19NO3
1-tert-Butyl 4-ethyl 5-oxoazepane-1,4-dicarboxylate
CAS 141642-82-2C14H23NO5
1-Methylazepan-4-one hydrochloride
CAS 19869-42-2C7H14ClNO
Ethyl 4-oxoazepane-3-carboxylate
CAS 740783-18-0C9H15NO3
1H-Azepine-1-carboxylic acid, hexahydro-4-oxo-, methyl ester
CAS 61995-24-2C8H13NO3
Diethyl 5-oxoazepane-1,4-dicarboxylate
CAS 19786-58-4C12H19NO5
1-Carbethoxyazepan-4-one
CAS 56515-89-0C9H15NO3
1-Ethylcarbonyl-4-oxohomopiperidine
CAS 1056124-09-4C9H15NO2
1-Acetylazepan-4-one
CAS 50492-23-4C8H13NO2
1-Ethyl-5-bromo-hexahydro-azepin-4-one hydrobromide
CAS 49569-40-6C8H15Br2NO
4H-Azepin-4-one, 5-bromo-1-ethylhexahydro-
CAS 792847-20-2C8H14BrNO
tert-Butyl 4-methyl-5-oxoazepane-1-carboxylate
CAS 1228450-21-2C12H21NO3
Ethyl 5-oxoazepane-4-carboxylate
CAS 19673-15-5C9H15NO3
Azepan-4-one hydrochloride
CAS 50492-22-3C6H12ClNO
Ethyl 4-oxoazepane-3-carboxylate hydrochloride
CAS 198419-09-9C9H16ClNO3
5-Bromoazepan-4-one hydrobromide
CAS 83613-48-3C6H11Br2NO
5-Bromoazepan-4-one
CAS 167757-56-4C6H10BrNO
1,3-Dimethylazepan-4-one
CAS 50709-37-0C8H15NO
1-tert-Butyl 3-ethyl 4-oxoazepane-1,3-dicarboxylate
CAS 98977-37-8C14H23NO5
- 1-(tert-Butyl)azepan-4-one767230-01-3C10H19NO
- 4H-Azepin-4-one, 2,2,7,7-tetraethylhexahydro-686778-12-1C14H27NO
- 1 supplierstert-Butyl 3-fluoro-4-oxoazepane-1-carboxylate644982-12-7C11H18FNO3
- 3-Methylazepan-4-one748712-34-7C7H13NO
- 5-Methylazepan-4-one1228531-43-8C7H13NO
- Methyl 2-(1-methyl-5-oxoazepan-4-yl)acetate14037-05-9C10H17NO3
- Ethyl 5-oxoazepane-4-carboxylate hydrochloride19673-14-4C9H16ClNO3
- 1-tert-Butyl 4-methyl 5-oxoazepane-1,4-dicarboxylate949922-65-0C13H21NO5
- tert-Butyl 4-bromo-5-oxoazepane-1-carboxylate1004764-82-2C11H18BrNO3
- 1-tert-Butyl 4-ethyl 6-methyl-5-oxoazepane-1,4-dicarboxylate884487-29-0C15H25NO5
- Methyl 1-methyl-5-oxoazepane-4-carboxylate1541050-36-5C9H15NO3
- tert-Butyl 3-bromo-4-oxo-azepane-1-carboxylate1363286-45-6C11H18BrNO3
- 6-Methylazepan-4-one1443282-67-4C7H13NO
- tert-Butyl 4-fluoro-5-oxoazepane-1-carboxylate1209780-32-4C11H18FNO3
- 1-tert-Butyl 4-ethyl 6-fluoro-5-oxoazepane-1,4-dicarboxylate644982-11-6C14H22FNO5
- 1-tert-Butyl 4-ethyl 4-fluoro-5-oxoazepane-1,4-dicarboxylate1209780-31-3C14H22FNO5
- 5-Methylazepan-4-one hydrochloride1228450-23-4C7H14ClNO
- 4-Methyl-5-oxo-azepane-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester1228450-19-8C15H25NO5
- 3-Fluoroazepan-4-one hydrochloride644982-13-8C6H11ClFNO
- 3-Fluoroazepan-4-one756475-16-8C6H10FNO
- 5-Hydroxy-1,3,3,6,6-pentamethylazepan-4-one88278-90-4C11H21NO2
- tert-Butyl 4-oxo-5-(trifluoromethyl)azepane-1-carboxylate1393584-90-1C12H18F3NO3
- tert-Butyl 4-(2-ethoxy-2-oxoethyl)-5-oxoazepane-1-carboxylate1369494-84-7C15H25NO5
- tert-Butyl 3-amino-4-oxoazepane-1-carboxylate1512132-41-0C11H20N2O3
Related scaffolds
Same ring framework with different atoms or bond orders
