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Murcko scaffold

Ring system with 4 rings and 22 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
11
With full pages
1
Scaffold SMILES

O=C(Nc1n[nH]c2nc3ccccc3cc12)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1n[nH]c2nc3ccccc3cc12)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

N-(1-Ethylpyrazolo[3,4-b]quinolin-3-yl)-4-methylbenzamide chemical structure, C20H18N4O, CAS 714235-69-5
N-(1-Ethylpyrazolo[3,4-b]quinolin-3-yl)-4-methylbenzamide
CAS 714235-69-5C20H18N4O
N-(1-Ethyl-8-methylpyrazolo[3,4-b]quinolin-3-yl)benzamide chemical structure, C20H18N4O, CAS 714254-36-1
N-(1-Ethyl-8-methylpyrazolo[3,4-b]quinolin-3-yl)benzamide
CAS 714254-36-1C20H18N4O
3,5-Dimethoxy-N-(7-methyl-1-propyl-1H-pyrazolo[3,4-b]quinolin-3-yl)benzamide chemical structure, C23H24N4O3, CAS 714916-74-2
3,5-Dimethoxy-N-(7-methyl-1-propyl-1H-pyrazolo[3,4-b]quinolin-3-yl)benzamide
CAS 714916-74-2C23H24N4O3
3-Methyl-N-(8-methyl-1-propyl-1H-pyrazolo[3,4-b]quinolin-3-yl)benzamide chemical structure, C22H22N4O, CAS 714934-93-7
3-Methyl-N-(8-methyl-1-propyl-1H-pyrazolo[3,4-b]quinolin-3-yl)benzamide
CAS 714934-93-7C22H22N4O
N-(1,7-Dimethylpyrazolo[3,4-b]quinolin-3-yl)-3,5-dimethoxybenzamide chemical structure, C21H20N4O3, CAS 714935-99-6
N-(1,7-Dimethylpyrazolo[3,4-b]quinolin-3-yl)-3,5-dimethoxybenzamide
CAS 714935-99-6C21H20N4O3
3,5-Dimethoxy-N-(1-propyl-1H-pyrazolo[3,4-b]quinolin-3-yl)benzamide chemical structure, C22H22N4O3, CAS 714936-56-8
3,5-Dimethoxy-N-(1-propyl-1H-pyrazolo[3,4-b]quinolin-3-yl)benzamide
CAS 714936-56-8C22H22N4O3
4-Chloro-N-(1,7-dimethylpyrazolo[3,4-b]quinolin-3-yl)benzamide chemical structure, C19H15ClN4O, CAS 714916-02-6
4-Chloro-N-(1,7-dimethylpyrazolo[3,4-b]quinolin-3-yl)benzamide
CAS 714916-02-6C19H15ClN4O
3,4,5-Trimethoxy-N-(7-methyl-1-propyl-1H-pyrazolo[3,4-b]quinolin-3-yl)benzamide chemical structure, C24H26N4O4, CAS 714232-91-4
3,4,5-Trimethoxy-N-(7-methyl-1-propyl-1H-pyrazolo[3,4-b]quinolin-3-yl)benzamide
CAS 714232-91-4C24H26N4O4
N-(1-Butylpyrazolo[3,4-b]quinolin-3-yl)-2-fluorobenzamide chemical structure, C21H19FN4O, CAS 573938-00-8
N-(1-Butylpyrazolo[3,4-b]quinolin-3-yl)-2-fluorobenzamide
CAS 573938-00-8C21H19FN4O
N-(1-Butyl-1H-pyrazolo[3,4-b]quinolin-3-yl)-2-methylbenzamide chemical structure, C22H22N4O, CAS 577996-18-0
N-(1-Butyl-1H-pyrazolo[3,4-b]quinolin-3-yl)-2-methylbenzamide
CAS 577996-18-0C22H22N4O
N-(1-Butyl-6-methylpyrazolo[3,4-b]quinolin-3-yl)-2-fluorobenzamide chemical structure, C22H21FN4O, CAS 5304-54-1
N-(1-Butyl-6-methylpyrazolo[3,4-b]quinolin-3-yl)-2-fluorobenzamide
CAS 5304-54-1C22H21FN4O