Murcko scaffold
Ring system with 4 rings and 21 atoms
48 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 21
- Chemicals
- 48
- With full pages
- 1
Scaffold SMILES
C(=Nn1ccc2nc3ccccc3nc21)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 48 chemicals
![2-Amino-N-hexyl-1-[(3-hydroxyphenyl)methylideneamino]pyrrolo[3,2-b]quinoxaline-3-carboxamide chemical structure, C24H26N6O2, CAS 4862-47-9](/s/LRHCCXDGPFNVQF-UHFFFAOYSA-N.svg)
2-Amino-N-hexyl-1-[(3-hydroxyphenyl)methylideneamino]pyrrolo[3,2-b]quinoxaline-3-carboxamide
CAS 4862-47-9C24H26N6O2
![2-Amino-1-[[(3-chlorophenyl)methylene]amino]-N-[3-(1-methylethoxy)propyl]-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C24H25ClN6O2, CAS 842972-38-7](/s/ATQVJZUXNJOAFF-UHFFFAOYSA-N.svg)
2-Amino-1-[[(3-chlorophenyl)methylene]amino]-N-[3-(1-methylethoxy)propyl]-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 842972-38-7C24H25ClN6O2
![(E)-N-Allyl-2-amino-1-((3-nitrobenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C21H17N7O3, CAS 714290-55-8](/s/XHKUYWBYXFBPBT-WYMPLXKRSA-N.svg)
(E)-N-Allyl-2-amino-1-((3-nitrobenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 714290-55-8C21H17N7O3
![(E)-2-Amino-1-((4-chlorobenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C21H19ClN6O2, CAS 799830-02-7](/s/OBKGLOUVGGFZKT-BRJLIKDPSA-N.svg)
(E)-2-Amino-1-((4-chlorobenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 799830-02-7C21H19ClN6O2
![(E)-2-Amino-1-((3,4-dimethoxybenzylidene)amino)-N-isobutyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C24H26N6O3, CAS 799836-35-4](/s/PBMBTASSGKQDMX-UVHMKAGCSA-N.svg)
(E)-2-Amino-1-((3,4-dimethoxybenzylidene)amino)-N-isobutyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 799836-35-4C24H26N6O3
![(E)-2-Amino-N-(3-methoxypropyl)-1-((4-methylbenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C23H24N6O2, CAS 799839-33-1](/s/TYVQKFDBSCKBSF-VULFUBBASA-N.svg)
(E)-2-Amino-N-(3-methoxypropyl)-1-((4-methylbenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 799839-33-1C23H24N6O2
![(E)-2-Amino-1-((4-(dimethylamino)benzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C23H25N7O2, CAS 799840-33-8](/s/XDYNVDKNWDUGTQ-VULFUBBASA-N.svg)
(E)-2-Amino-1-((4-(dimethylamino)benzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 799840-33-8C23H25N7O2
![(E)-2-Amino-1-((4-isopropylbenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C24H26N6O2, CAS 835907-60-3](/s/OHINXQGIFIRXPZ-MZJWZYIUSA-N.svg)
(E)-2-Amino-1-((4-isopropylbenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 835907-60-3C24H26N6O2
![(E)-2-Amino-N-(3-methoxypropyl)-1-((2-methylbenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C23H24N6O2, CAS 835910-10-6](/s/REORDDBMFJHGHE-VULFUBBASA-N.svg)
(E)-2-Amino-N-(3-methoxypropyl)-1-((2-methylbenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 835910-10-6C23H24N6O2
![(E)-2-Amino-N-butyl-1-((3,4-dimethoxybenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C24H26N6O3, CAS 835910-84-4](/s/KFQJMHJDNNFXKU-MZJWZYIUSA-N.svg)
(E)-2-Amino-N-butyl-1-((3,4-dimethoxybenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 835910-84-4C24H26N6O3
![(E)-2-Amino-N-(3-methoxypropyl)-1-((3-nitrobenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C22H21N7O4, CAS 835911-83-6](/s/XYYYNKMPDICGKS-DHRITJCHSA-N.svg)
(E)-2-Amino-N-(3-methoxypropyl)-1-((3-nitrobenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 835911-83-6C22H21N7O4
![(E)-2-Amino-N-(3-methoxypropyl)-1-((3-methylbenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C23H24N6O2, CAS 836624-84-1](/s/RPTAQFXSQKRMJZ-VULFUBBASA-N.svg)
(E)-2-Amino-N-(3-methoxypropyl)-1-((3-methylbenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 836624-84-1C23H24N6O2
![(E)-2-Amino-1-((4-(dimethylamino)benzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C24H27N7O2, CAS 836625-15-1](/s/YJQQOWZTEFRJSJ-JFLMPSFJSA-N.svg)
(E)-2-Amino-1-((4-(dimethylamino)benzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 836625-15-1C24H27N7O2
![(E)-2-Amino-1-((3-methoxybenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C22H22N6O3, CAS 836630-16-1](/s/HUFNLRZVFYFKKD-DHRITJCHSA-N.svg)
(E)-2-Amino-1-((3-methoxybenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 836630-16-1C22H22N6O3
![(E)-2-Amino-1-((4-fluorobenzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C22H21FN6O2, CAS 836630-22-9](/s/ARQDSKCBRYWQCI-LGJNPRDNSA-N.svg)
(E)-2-Amino-1-((4-fluorobenzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 836630-22-9C22H21FN6O2
![(E)-2-Amino-1-((4-ethoxybenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C23H24N6O3, CAS 836639-79-3](/s/GSLHOMIDPBWFEP-VULFUBBASA-N.svg)
(E)-2-Amino-1-((4-ethoxybenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 836639-79-3C23H24N6O3
![(E)-2-Amino-1-((3-hydroxybenzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C22H22N6O3, CAS 836641-26-0](/s/LBIXZULMAYTRSB-DHRITJCHSA-N.svg)
(E)-2-Amino-1-((3-hydroxybenzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 836641-26-0C22H22N6O3
![(E)-2-Amino-1-((2,3-dimethoxybenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C23H24N6O4, CAS 836643-10-8](/s/XDTKXCMGGMUZGC-LGJNPRDNSA-N.svg)
(E)-2-Amino-1-((2,3-dimethoxybenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 836643-10-8C23H24N6O4
![(E)-2-Amino-1-((4-ethoxybenzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C24H26N6O3, CAS 836645-43-3](/s/YAKKEHOLICFIMV-JFLMPSFJSA-N.svg)
(E)-2-Amino-1-((4-ethoxybenzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 836645-43-3C24H26N6O3
![(E)-2-Amino-N-(2-methoxyethyl)-1-((4-methylbenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C22H22N6O2, CAS 836649-94-6](/s/PFKZCHQBVWDNJP-DHRITJCHSA-N.svg)
(E)-2-Amino-N-(2-methoxyethyl)-1-((4-methylbenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 836649-94-6C22H22N6O2
![(E)-2-Amino-1-(benzylideneamino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C22H22N6O2, CAS 839699-15-9](/s/WKJAOTLQXLJFRY-AFUMVMLFSA-N.svg)
(E)-2-Amino-1-(benzylideneamino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 839699-15-9C22H22N6O2
![(E)-2-Amino-N-butyl-1-((3-hydroxybenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C22H22N6O2, CAS 839699-51-3](/s/KJYVCCPDWRQQML-DHRITJCHSA-N.svg)
(E)-2-Amino-N-butyl-1-((3-hydroxybenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 839699-51-3C22H22N6O2
![(E)-2-Amino-N-(2-methoxyethyl)-1-((3-methylbenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C22H22N6O2, CAS 839699-61-5](/s/YYNYICKSAIPQLB-DHRITJCHSA-N.svg)
(E)-2-Amino-N-(2-methoxyethyl)-1-((3-methylbenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 839699-61-5C22H22N6O2
![(E)-2-Amino-1-((3-chlorobenzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C22H21ClN6O2, CAS 839700-43-5](/s/AYDNWOHMGYBRSY-LGJNPRDNSA-N.svg)
(E)-2-Amino-1-((3-chlorobenzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 839700-43-5C22H21ClN6O2
- (E)-2-Amino-1-((4-fluorobenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide840457-00-3C21H19FN6O2
- (E)-2-Amino-1-((2-methoxybenzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide840457-22-9C23H24N6O3
- (E)-2-Amino-1-((4-chlorobenzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide840458-97-1C22H21ClN6O2
- (E)-2-Amino-1-((3,4-dimethoxybenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide840460-75-5C23H24N6O4
- (E)-2-Amino-1-(benzylideneamino)-N-(3-isopropoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide840516-74-7C24H26N6O2
- (E)-N-Allyl-2-amino-1-((2-methoxybenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide587004-27-1C22H20N6O2
- (E)-2-Amino-1-((3-methoxybenzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide836633-27-3C23H24N6O3
- (E)-2-Amino-N-(sec-butyl)-1-((3-hydroxybenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide573695-69-9C22H22N6O2
- (E)-2-Amino-N-butyl-1-((2,3-dimethoxybenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide836625-82-2C24H26N6O3
- (E)-2-Amino-1-((2,3-dimethoxybenzylidene)amino)-N-isobutyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide836638-83-6C24H26N6O3
- (E)-2-Amino-1-((3-hydroxybenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide836630-67-2C21H20N6O3
- (E)-2-Amino-1-((3-hydroxybenzylidene)amino)-N-isobutyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide836640-39-2C22H22N6O2
- (E)-2-Amino-1-((3-chlorobenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide836625-75-3C21H19ClN6O2
- (E)-2-Amino-N-(sec-butyl)-1-((3,4-dimethoxybenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide587014-15-1C24H26N6O3
- (E)-Methyl 4-(((2-amino-3-((2-methoxyethyl)carbamoyl)-1H-pyrrolo[2,3-b]quinoxalin-1-yl)imino)methyl)benzoate836635-81-5C23H22N6O4
- (E)-2-Amino-N-butyl-1-((3,4-dihydroxybenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide836626-65-4C22H22N6O3
- (E)-2-Amino-1-((3,4-dihydroxybenzylidene)amino)-N-isobutyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide836638-15-4C22H22N6O3
- (E)-2-Amino-1-((3,4-dihydroxybenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide835910-79-7C21H20N6O4
- (E)-2-Amino-1-((3-ethoxy-4-hydroxybenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide840460-60-8C23H24N6O4
- (E)-2-Amino-1-((3,4-dihydroxybenzylidene)amino)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide840457-44-5C22H22N6O4
- (E)-2-Amino-1-((2-hydroxybenzylidene)amino)-N-(3-isopropoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide579441-54-6C24H26N6O3
- (E)-2-Amino-N-(sec-butyl)-1-((3,4-dihydroxybenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide714925-27-6C22H22N6O3
- (E)-N-Allyl-2-amino-1-((2-hydroxybenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide578736-15-9C21H18N6O2
- (E)-2-Amino-N-(sec-butyl)-1-((2-hydroxybenzylidene)amino)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide575469-07-7C22H22N6O2
Related scaffolds
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