CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 23 atoms

4 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
4
With full pages
1
Scaffold SMILES

O=C1C=CCC2Cc3onc(OCc4ccccc4)c3C(=O)C12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CCC2Cc3onc(OCc4ccccc4)c3C(=O)C12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

(4aS,8aS,9S)-3-(Benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-4H,4aH,5H,8H,9H-naphtho(2,3-d)(1,2)oxazole-4,5-dione chemical structure, C26H34N2O5Si, CAS 852821-06-8
(4aS,8aS,9S)-3-(Benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-4H,4aH,5H,8H,9H-naphtho(2,3-d)(1,2)oxazole-4,5-dione
CAS 852821-06-8C26H34N2O5Si
Naphth[2,3-d]isoxazole-4,5(4aH,8H)-dione, 9-(diethylamino)-4a-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-8a,9-dihydro-3-(phenylmethoxy)-, (4aS,8aS,9S)- chemical structure, C28H38N2O5Si, CAS 1575491-01-8
Naphth[2,3-d]isoxazole-4,5(4aH,8H)-dione, 9-(diethylamino)-4a-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-8a,9-dihydro-3-(phenylmethoxy)-, (4aS,8aS,9S)-
CAS 1575491-01-8C28H38N2O5Si
(4aR,8aS,9S)-4a-[tert-Butyl(dimethyl)silyl]oxy-9-(diethylamino)-3-phenylmethoxy-8a,9-dihydro-8H-benzo[f][1,2]benzoxazole-4,5-dione chemical structure, C28H38N2O5Si
(4aR,8aS,9S)-4a-[tert-Butyl(dimethyl)silyl]oxy-9-(diethylamino)-3-phenylmethoxy-8a,9-dihydro-8H-benzo[f][1,2]benzoxazole-4,5-dione
C28H38N2O5Si
4a-[tert-Butyl(dimethyl)silyl]oxy-9-(diethylamino)-3-phenylmethoxy-8a,9-dihydro-8H-benzo[f][1,2]benzoxazole-4,5-dione chemical structure, C28H38N2O5Si
4a-[tert-Butyl(dimethyl)silyl]oxy-9-(diethylamino)-3-phenylmethoxy-8a,9-dihydro-8H-benzo[f][1,2]benzoxazole-4,5-dione
C28H38N2O5Si