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Murcko scaffold

6-(Furan-2-yl)pyridin-2(1H)-one scaffold

9 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
9
With full pages
3
Scaffold SMILES

O=c1cccc(-c2ccco2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-(Furan-2-yl)pyridin-2(1H)-one page
Murcko scaffold O=c1cccc(-c2ccco2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

6-(2-Furyl)-2-hydroxy-4-(trifluoromethyl)nicotinonitrile chemical structure, C11H5F3N2O2, CAS 372977-36-1
6-(2-Furyl)-2-hydroxy-4-(trifluoromethyl)nicotinonitrile
CAS 372977-36-1C11H5F3N2O2
6-(Furan-2-yl)-2-hydroxy-4-(methylthio)nicotinonitrile chemical structure, C11H8N2O2S, CAS 261761-63-1
6-(Furan-2-yl)-2-hydroxy-4-(methylthio)nicotinonitrile
CAS 261761-63-1C11H8N2O2S
6-(Furan-2-yl)-2-oxo-1,2-dihydropyridine-3-carbonitrile chemical structure, C10H6N2O2, CAS 56304-75-7
6-(Furan-2-yl)-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS 56304-75-7C10H6N2O2
Ethyl 3-cyano-6-(furan-2-yl)-2-hydroxypyridine-4-carboxylate chemical structure, C13H10N2O4, CAS 57696-15-8
Ethyl 3-cyano-6-(furan-2-yl)-2-hydroxypyridine-4-carboxylate
CAS 57696-15-8C13H10N2O4
6-(2-Furanyl)-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid chemical structure, C10H7NO4, CAS 56304-44-0
6-(2-Furanyl)-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid
CAS 56304-44-0C10H7NO4
6-(Furan-2-yl)pyridin-2(1H)-one chemical structure, C9H7NO2, CAS 41220-24-0
6-(Furan-2-yl)pyridin-2(1H)-one
CAS 41220-24-0C9H7NO2
Methyl 6-(2-furyl)-2-hydroxynicotinate chemical structure, C11H9NO4, CAS 1202163-29-8
Methyl 6-(2-furyl)-2-hydroxynicotinate
CAS 1202163-29-8C11H9NO4
Methyl 3-cyano-6-(furan-2-yl)-2-oxo-1,2-dihydropyridine-4-carboxylate chemical structure, C12H8N2O4, CAS 2098054-41-0
Methyl 3-cyano-6-(furan-2-yl)-2-oxo-1,2-dihydropyridine-4-carboxylate
CAS 2098054-41-0C12H8N2O4
3-Cyano-6-(furan-2-yl)-2-oxo-1,2-dihydropyridine-4-carboxylic acid chemical structure, C11H6N2O4, CAS 2098101-61-0
3-Cyano-6-(furan-2-yl)-2-oxo-1,2-dihydropyridine-4-carboxylic acid
CAS 2098101-61-0C11H6N2O4