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Murcko scaffold

Ring system with 2 rings and 14 atoms

20 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
20
With full pages
6
Scaffold SMILES

O=C(Nc1ncns1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ncns1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

4-Fluoro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C12H10FN3O2S, CAS 690991-52-7
4-Fluoro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 690991-52-7C12H10FN3O2S
N-[3-(2-Oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C12H11N3O2S, CAS 110196-91-3
N-[3-(2-Oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 110196-91-3C12H11N3O2S
2,4-Dichloro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C12H9Cl2N3O2S, CAS 743472-76-6
2,4-Dichloro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 743472-76-6C12H9Cl2N3O2S
2-Chloro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C12H10ClN3O2S, CAS 736167-30-9
2-Chloro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 736167-30-9C12H10ClN3O2S
3-Chloro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C12H10ClN3O2S, CAS 866013-77-6
3-Chloro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 866013-77-6C12H10ClN3O2S
4-Chloro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C12H10ClN3O2S, CAS 866013-78-7
4-Chloro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 866013-78-7C12H10ClN3O2S
2-Fluoro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C12H10FN3O2S, CAS 736167-28-5
2-Fluoro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 736167-28-5C12H10FN3O2S
3-Fluoro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C12H10FN3O2S, CAS 866013-79-8
3-Fluoro-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 866013-79-8C12H10FN3O2S
4-Methyl-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C13H13N3O2S, CAS 120765-20-0
4-Methyl-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 120765-20-0C13H13N3O2S
4-tert-Butyl-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C16H19N3O2S, CAS 866013-80-1
4-tert-Butyl-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 866013-80-1C16H19N3O2S
3,5-Dimethoxy-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C14H15N3O4S, CAS 901002-59-3
3,5-Dimethoxy-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 901002-59-3C14H15N3O4S
2-Ethoxy-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C14H15N3O3S, CAS 874464-75-2
2-Ethoxy-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 874464-75-2C14H15N3O3S
N-Butyl-N-(3-methyl-1,2,4-thiadiazol-5-yl)benzamide chemical structure, C14H17N3OS, CAS 62347-30-2
N-Butyl-N-(3-methyl-1,2,4-thiadiazol-5-yl)benzamide
CAS 62347-30-2C14H17N3OS
N-[3-(2-Hydroxypropyl)-1,2,4-thiadiazol-5-yl]-4-methylbenzamide chemical structure, C13H15N3O2S, CAS 931362-70-8
N-[3-(2-Hydroxypropyl)-1,2,4-thiadiazol-5-yl]-4-methylbenzamide
CAS 931362-70-8C13H15N3O2S
4-Chloro-N-[3-(2-hydroxypropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C12H12ClN3O2S, CAS 931722-29-1
4-Chloro-N-[3-(2-hydroxypropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 931722-29-1C12H12ClN3O2S
2-Chloro-N-[3-(2-hydroxypropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C12H12ClN3O2S, CAS 931333-70-9
2-Chloro-N-[3-(2-hydroxypropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 931333-70-9C12H12ClN3O2S
3,4-Dimethyl-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C14H15N3O2S, CAS 1255785-13-7
3,4-Dimethyl-N-[3-(2-oxopropyl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 1255785-13-7C14H15N3O2S
3-Hydroxy-5-isopropoxy-N-(3-methyl-1,2,4-thiadiazol-5-yl)benzamide chemical structure, C13H15N3O3S, CAS 863454-86-8
3-Hydroxy-5-isopropoxy-N-(3-methyl-1,2,4-thiadiazol-5-yl)benzamide
CAS 863454-86-8C13H15N3O3S
3-Chloro-4-hydroxy-N-(3-methyl-1,2,4-thiadiazol-5-yl)benzamide chemical structure, C10H8ClN3O2S, CAS 1384673-05-5
3-Chloro-4-hydroxy-N-(3-methyl-1,2,4-thiadiazol-5-yl)benzamide
CAS 1384673-05-5C10H8ClN3O2S
2-Methyl-N-(1,2,4-thiadiazol-5-yl)benzamide chemical structure, C10H9N3OS, CAS 1620337-25-8
2-Methyl-N-(1,2,4-thiadiazol-5-yl)benzamide
CAS 1620337-25-8C10H9N3OS