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Murcko scaffold

1-Phenyl-6-sulfanyl-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one scaffold

32 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 17
Chemicals: 32
With full pages: 3

Scaffold SMILES

O=c1[nH]c(=S)[nH]c2c1cnn2-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1-Phenyl-6-sulfanyl-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one page

Murcko scaffold O=c1[nH]c(=S)[nH]c2c1cnn2-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

1-(4-Fluorophenyl)-6-mercapto-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one chemical structure, C11H7FN4OS, CAS 289651-64-5

1-(4-Fluorophenyl)-6-mercapto-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

CAS 289651-64-5C₁₁H₇FN₄OS

1-Phenyl-6-sulfanyl-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one chemical structure, C11H8N4OS, CAS 156718-77-3

1-Phenyl-6-sulfanyl-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one

CAS 156718-77-3C₁₁H₈N₄OS

6-Mercapto-1-(4-methylphenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one chemical structure, C12H10N4OS, CAS 923784-01-4

6-Mercapto-1-(4-methylphenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

CAS 923784-01-4C₁₂H₁₀N₄OS

1-(3-Chlorophenyl)-6-sulfanyl-1H,4H,5H-pyrazolo(3,4-d)pyrimidin-4-one chemical structure, C11H7ClN4OS, CAS 929973-42-2

1-(3-Chlorophenyl)-6-sulfanyl-1H,4H,5H-pyrazolo(3,4-d)pyrimidin-4-one

CAS 929973-42-2C₁₁H₇ClN₄OS

1-(4-Chlorophenyl)-6-mercapto-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one chemical structure, C11H7ClN4OS, CAS 941868-08-2

1-(4-Chlorophenyl)-6-mercapto-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

CAS 941868-08-2C₁₁H₇ClN₄OS

6-Mercapto-1-(2-methoxyphenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one chemical structure, C12H10N4O2S, CAS 1105196-23-3

6-Mercapto-1-(2-methoxyphenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

CAS 1105196-23-3C₁₂H₁₀N₄O₂S

1-(3,4-Dimethylphenyl)-6-mercapto-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one chemical structure, C13H12N4OS, CAS 1105189-44-3

1-(3,4-Dimethylphenyl)-6-mercapto-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

CAS 1105189-44-3C₁₃H₁₂N₄OS

6-Mercapto-1-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol chemical structure, C12H10N4O2S, CAS 1044140-07-9

6-Mercapto-1-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol

CAS 1044140-07-9C₁₂H₁₀N₄O₂S

6-Mercapto-1-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol chemical structure, C12H10N4O2S, CAS 1044140-06-8

6-Mercapto-1-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol

CAS 1044140-06-8C₁₂H₁₀N₄O₂S

1-(3-Bromophenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C11H7BrN4OS, CAS 1416342-23-8

1-(3-Bromophenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416342-23-8C₁₁H₇BrN₄OS

1-(4-Fluoro-2-methylphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C12H9FN4OS, CAS 1416348-36-1

1-(4-Fluoro-2-methylphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416348-36-1C₁₂H₉FN₄OS

1-(2,4-Dimethylphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C13H12N4OS, CAS 1416345-82-8

1-(2,4-Dimethylphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416345-82-8C₁₃H₁₂N₄OS

1-(2,5-Dimethylphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C13H12N4OS, CAS 1416340-80-1

1-(2,5-Dimethylphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416340-80-1C₁₃H₁₂N₄OS

1-(5-Chloro-2-methylphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C12H9ClN4OS, CAS 1416346-20-7

1-(5-Chloro-2-methylphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416346-20-7C₁₂H₉ClN₄OS

1-(4-Bromophenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C11H7BrN4OS, CAS 1404364-58-4

1-(4-Bromophenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1404364-58-4C₁₁H₇BrN₄OS

6-Mercapto-1-(m-tolyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C12H10N4OS, CAS 1416344-86-9

6-Mercapto-1-(m-tolyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416344-86-9C₁₂H₁₀N₄OS

1-(2,3-Dimethylphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C13H12N4OS, CAS 1416339-45-1

1-(2,3-Dimethylphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416339-45-1C₁₃H₁₂N₄OS

1-(2,5-Dimethoxyphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C13H12N4O3S, CAS 1416342-33-0

1-(2,5-Dimethoxyphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416342-33-0C₁₃H₁₂N₄O₃S

1-(2-Fluorophenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C11H7FN4OS, CAS 1416345-80-6

1-(2-Fluorophenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416345-80-6C₁₁H₇FN₄OS

1-(2-Chlorophenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C11H7ClN4OS, CAS 1416340-88-9

1-(2-Chlorophenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416340-88-9C₁₁H₇ClN₄OS

1-(3-Fluorophenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C11H7FN4OS, CAS 1416342-35-2

1-(3-Fluorophenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416342-35-2C₁₁H₇FN₄OS

1-(3-Chloro-2-methylphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C12H9ClN4OS, CAS 1416340-96-9

1-(3-Chloro-2-methylphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416340-96-9C₁₂H₉ClN₄OS

6-Mercapto-1-(2-methoxy-5-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C13H12N4O2S, CAS 1416345-88-4

6-Mercapto-1-(2-methoxy-5-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416345-88-4C₁₃H₁₂N₄O₂S

1-(3-Chloro-4-methoxyphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C12H9ClN4O2S, CAS 1416344-94-9

1-(3-Chloro-4-methoxyphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 1416344-94-9C₁₂H₉ClN₄O₂S