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Murcko scaffold

5-Phenyl-3H,4H-thieno[2,3-d]pyrimidin-4-one scaffold

128 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
128
With full pages
45
Scaffold SMILES

O=c1[nH]cnc2scc(-c3ccccc3)c12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Phenyl-3H,4H-thieno[2,3-d]pyrimidin-4-one page
Murcko scaffold O=c1[nH]cnc2scc(-c3ccccc3)c12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 128 chemicals

Thieno(2,3-d)pyrimidin-4(3H)-one, 3-amino-2-methyl-5-phenyl- chemical structure, C13H11N3OS, CAS 43088-51-3
Thieno(2,3-d)pyrimidin-4(3H)-one, 3-amino-2-methyl-5-phenyl-
CAS 43088-51-3C13H11N3OS
5-Phenyl-3H,4H-thieno[2,3-d]pyrimidin-4-one chemical structure, C12H8N2OS, CAS 35978-39-3
5-Phenyl-3H,4H-thieno[2,3-d]pyrimidin-4-one
CAS 35978-39-3C12H8N2OS
5-(3-Methoxyphenyl)thieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C13H10N2O2S, CAS 282104-83-0
5-(3-Methoxyphenyl)thieno[2,3-d]pyrimidin-4(3H)-one
CAS 282104-83-0C13H10N2O2S
3-Amino-5-phenyl-2-propylthieno[2,3-d]pyrimidin-4-one chemical structure, C15H15N3OS, CAS 342383-95-3
3-Amino-5-phenyl-2-propylthieno[2,3-d]pyrimidin-4-one
CAS 342383-95-3C15H15N3OS
3-Amino-5-(4-chloro-phenyl)-3H-thieno[2,3-d]pyrimidin-4-one chemical structure, C12H8ClN3OS, CAS 307340-75-6
3-Amino-5-(4-chloro-phenyl)-3H-thieno[2,3-d]pyrimidin-4-one
CAS 307340-75-6C12H8ClN3OS
3-Amino-2-methyl-5-(4-methylphenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one chemical structure, C14H13N3OS, CAS 300818-36-4
3-Amino-2-methyl-5-(4-methylphenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one
CAS 300818-36-4C14H13N3OS
3-Amino-5-phenyl-3H,4H-thieno[2,3-d]pyrimidin-4-one chemical structure, C12H9N3OS, CAS 306280-98-8
3-Amino-5-phenyl-3H,4H-thieno[2,3-d]pyrimidin-4-one
CAS 306280-98-8C12H9N3OS
5-(4-Isopropyl-phenyl)-3H-thieno[2,3-d]pyrimidin-4-one chemical structure, C15H14N2OS, CAS 315684-18-5
5-(4-Isopropyl-phenyl)-3H-thieno[2,3-d]pyrimidin-4-one
CAS 315684-18-5C15H14N2OS
3-Amino-5-(4-tert-butylphenyl)-2-methylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C17H19N3OS, CAS 315684-46-9
3-Amino-5-(4-tert-butylphenyl)-2-methylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 315684-46-9C17H19N3OS
3-Amino-5-(4-chlorophenyl)-2-methyl-3H,4H-thieno[2,3-d]pyrimidin-4-one chemical structure, C13H10ClN3OS, CAS 315711-16-1
3-Amino-5-(4-chlorophenyl)-2-methyl-3H,4H-thieno[2,3-d]pyrimidin-4-one
CAS 315711-16-1C13H10ClN3OS
6-Methyl-5-phenyl-3H,4H-thieno(2,3-d)pyrimidin-4-one chemical structure, C13H10N2OS, CAS 35978-38-2
6-Methyl-5-phenyl-3H,4H-thieno(2,3-d)pyrimidin-4-one
CAS 35978-38-2C13H10N2OS
2-[4-Oxo-5-(p-tolyl)thieno[2,3-d]pyrimidin-3-yl]acetic acid chemical structure, C15H12N2O3S, CAS 446830-91-7
2-[4-Oxo-5-(p-tolyl)thieno[2,3-d]pyrimidin-3-yl]acetic acid
CAS 446830-91-7C15H12N2O3S
5-(3-Nitrophenyl)-3-propylthieno[2,3-d]pyrimidin-4-one chemical structure, C15H13N3O3S, CAS 449191-88-2
5-(3-Nitrophenyl)-3-propylthieno[2,3-d]pyrimidin-4-one
CAS 449191-88-2C15H13N3O3S
5-(3,4-Dimethylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C14H12N2OS, CAS 433949-07-6
5-(3,4-Dimethylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one
CAS 433949-07-6C14H12N2OS
5-(2,4-Dimethylphenyl)thieno[2,3-d]pyrimidin-4(1H)-one chemical structure, C14H12N2OS, CAS 17537-74-5
5-(2,4-Dimethylphenyl)thieno[2,3-d]pyrimidin-4(1H)-one
CAS 17537-74-5C14H12N2OS
5-(4-Chlorophenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C13H9ClN2OS, CAS 379241-59-5
5-(4-Chlorophenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 379241-59-5C13H9ClN2OS
5-(4-Fluorophenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C13H9FN2OS, CAS 379236-06-3
5-(4-Fluorophenyl)-6-methylthieno[2,3-d]pyrimidin-4(3H)-one
CAS 379236-06-3C13H9FN2OS
2-Methyl-5-phenyl-3H-thieno[2,3-d]pyrimidin-4-one chemical structure, C13H10N2OS, CAS 18593-67-4
2-Methyl-5-phenyl-3H-thieno[2,3-d]pyrimidin-4-one
CAS 18593-67-4C13H10N2OS
3-Amino-2-ethyl-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-4-one chemical structure, C14H13N3OS, CAS 43088-56-8
3-Amino-2-ethyl-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-4-one
CAS 43088-56-8C14H13N3OS
5-(4-Ethylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C14H12N2OS, CAS 17509-22-7
5-(4-Ethylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one
CAS 17509-22-7C14H12N2OS
Cambridge id 6943495 chemical structure, C12H7N3O3S, CAS 371219-73-7
Cambridge id 6943495
CAS 371219-73-7C12H7N3O3S
5-(4-Fluorophenyl)-3H,4H-thieno(2,3-d)pyrimidin-4-one chemical structure, C12H7FN2OS, CAS 35978-37-1
5-(4-Fluorophenyl)-3H,4H-thieno(2,3-d)pyrimidin-4-one
CAS 35978-37-1C12H7FN2OS
5-(4-Bromophenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one chemical structure, C12H7BrN2OS, CAS 307512-24-9
5-(4-Bromophenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one
CAS 307512-24-9C12H7BrN2OS
3-Amino-5-(3,4-dimethoxyphenyl)-2-methyl-3H,4H-thieno[2,3-d]pyrimidin-4-one chemical structure, C15H15N3O3S, CAS 307512-25-0
3-Amino-5-(3,4-dimethoxyphenyl)-2-methyl-3H,4H-thieno[2,3-d]pyrimidin-4-one
CAS 307512-25-0C15H15N3O3S