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Murcko scaffold

3-Phenylpyrazolo[1,5-a]pyrimidine scaffold

619 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
619
With full pages
64
Scaffold SMILES

c1ccc(-c2cnn3cccnc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylpyrazolo[1,5-a]pyrimidine page
Murcko scaffold c1ccc(-c2cnn3cccnc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 619 chemicals

2,5,7-Trimethyl-3-phenylpyrazolo[1,5-a]pyrimidine chemical structure, C15H15N3, CAS 138628-46-3
2,5,7-Trimethyl-3-phenylpyrazolo[1,5-a]pyrimidine
CAS 138628-46-3C15H15N3
7-Amino-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidine-6-carbonitrile chemical structure, C14H11N5, CAS 387361-34-4
7-Amino-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidine-6-carbonitrile
CAS 387361-34-4C14H11N5
7-tert-Butyl-2,5,6-trimethyl-3-phenylpyrazolo[1,5-a]pyrimidine chemical structure, C19H23N3, CAS 361375-43-1
7-tert-Butyl-2,5,6-trimethyl-3-phenylpyrazolo[1,5-a]pyrimidine
CAS 361375-43-1C19H23N3
5-tert-Butyl-2-methyl-3-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C18H18F3N3, CAS 402572-93-4
5-tert-Butyl-2-methyl-3-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 402572-93-4C18H18F3N3
1-(7-Methyl-3-phenylpyrazolo[1,5-a]pyrimidin-6-yl)ethanone chemical structure, C15H13N3O, CAS 130506-84-2
1-(7-Methyl-3-phenylpyrazolo[1,5-a]pyrimidin-6-yl)ethanone
CAS 130506-84-2C15H13N3O
Ethyl 7-amino-3-phenylpyrazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C15H14N4O2, CAS 698977-10-5
Ethyl 7-amino-3-phenylpyrazolo[1,5-a]pyrimidine-6-carboxylate
CAS 698977-10-5C15H14N4O2
Ethyl 7-amino-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C16H16N4O2, CAS 727421-94-5
Ethyl 7-amino-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidine-6-carboxylate
CAS 727421-94-5C16H16N4O2
2-(2-((3-(4-Chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl)amino)ethoxy)ethanol chemical structure, C17H19ClN4O2, CAS 896592-23-7
2-(2-((3-(4-Chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl)amino)ethoxy)ethanol
CAS 896592-23-7C17H19ClN4O2
5,7-Dimethyl-3-phenylpyrazolo[1,5-a]pyrimidine chemical structure, C14H13N3, CAS 61552-61-2
5,7-Dimethyl-3-phenylpyrazolo[1,5-a]pyrimidine
CAS 61552-61-2C14H13N3
5-Methyl-3-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C14H10F3N3, CAS 299919-03-2
5-Methyl-3-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 299919-03-2C14H10F3N3
5,7-Dimethyl-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C15H12F3N3, CAS 689216-68-0
5,7-Dimethyl-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 689216-68-0C15H12F3N3
3-(4-Chlorophenyl)-2,5,7-trimethylpyrazolo[1,5-a]pyrimidine chemical structure, C15H14ClN3, CAS 419546-69-3
3-(4-Chlorophenyl)-2,5,7-trimethylpyrazolo[1,5-a]pyrimidine
CAS 419546-69-3C15H14ClN3
7-Amino-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidine-6-carbonitrile chemical structure, C14H10ClN5, CAS 767346-80-5
7-Amino-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidine-6-carbonitrile
CAS 767346-80-5C14H10ClN5
3-(4-Chlorophenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine chemical structure, C14H12ClN3, CAS 700351-26-4
3-(4-Chlorophenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine
CAS 700351-26-4C14H12ClN3
2-(5,7-Dimethyl-3-phenyl-6-pyrazolo[1,5-a]pyrimidinyl)acetic acid ethyl ester chemical structure, C18H19N3O2, CAS 700351-27-5
2-(5,7-Dimethyl-3-phenyl-6-pyrazolo[1,5-a]pyrimidinyl)acetic acid ethyl ester
CAS 700351-27-5C18H19N3O2
Ethyl [3-(4-chlorophenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-6-yl]acetate chemical structure, C18H18ClN3O2, CAS 434297-08-2
Ethyl [3-(4-chlorophenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-6-yl]acetate
CAS 434297-08-2C18H18ClN3O2
Ethyl 3-(4-chlorophenyl)-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C16H14ClN3O2, CAS 173678-19-8
Ethyl 3-(4-chlorophenyl)-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate
CAS 173678-19-8C16H14ClN3O2
1-(2,7-Dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-6-yl)ethanone chemical structure, C16H15N3O, CAS 309938-92-9
1-(2,7-Dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-6-yl)ethanone
CAS 309938-92-9C16H15N3O
3-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C14H7F6N3, CAS 70594-15-9
3-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 70594-15-9C14H7F6N3
1-[3-(4-Chlorophenyl)-2,7-dimethylpyrazolo[1,5-a]pyrimidin-6-yl]ethanone chemical structure, C16H14ClN3O, CAS 432524-92-0
1-[3-(4-Chlorophenyl)-2,7-dimethylpyrazolo[1,5-a]pyrimidin-6-yl]ethanone
CAS 432524-92-0C16H14ClN3O
1-[3-(3-Bromophenyl)-7-methylpyrazolo[1,5-a]pyrimidin-6-yl]ethanone chemical structure, C15H12BrN3O, CAS 432528-86-4
1-[3-(3-Bromophenyl)-7-methylpyrazolo[1,5-a]pyrimidin-6-yl]ethanone
CAS 432528-86-4C15H12BrN3O
2,7-Dimethyl-3-phenylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid chemical structure, C15H13N3O2, CAS 853104-06-0
2,7-Dimethyl-3-phenylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid
CAS 853104-06-0C15H13N3O2
Ethyl 3-(4-chlorophenyl)-2,7-dimethylpyrazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C17H16ClN3O2, CAS 432503-47-4
Ethyl 3-(4-chlorophenyl)-2,7-dimethylpyrazolo[1,5-a]pyrimidine-6-carboxylate
CAS 432503-47-4C17H16ClN3O2
7-tert-Butyl-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidine chemical structure, C17H19N3, CAS 722462-52-4
7-tert-Butyl-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidine
CAS 722462-52-4C17H19N3